ZA894828B - Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity - Google Patents

Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity

Info

Publication number
ZA894828B
ZA894828B ZA894828A ZA894828A ZA894828B ZA 894828 B ZA894828 B ZA 894828B ZA 894828 A ZA894828 A ZA 894828A ZA 894828 A ZA894828 A ZA 894828A ZA 894828 B ZA894828 B ZA 894828B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical agents
ibuprofen
throat
elimination
burning
Prior art date
Application number
ZA894828A
Other languages
English (en)
Inventor
Mario Carcano
Carcano Mario
Massimo Costa
Costa Massimo
Original Assignee
Aesculapius Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4238447&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA894828(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aesculapius Pharma Sa filed Critical Aesculapius Pharma Sa
Publication of ZA894828B publication Critical patent/ZA894828B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA894828A 1988-07-12 1989-06-26 Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity ZA894828B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2647/88A CH677606A5 (cs) 1988-07-12 1988-07-12

Publications (1)

Publication Number Publication Date
ZA894828B true ZA894828B (en) 1990-03-28

Family

ID=4238447

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894828A ZA894828B (en) 1988-07-12 1989-06-26 Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity

Country Status (11)

Country Link
US (1) US5180590A (cs)
EP (1) EP0351353B1 (cs)
JP (1) JPH07112973B2 (cs)
AT (1) ATE73656T1 (cs)
CA (1) CA1336323C (cs)
CH (1) CH677606A5 (cs)
DE (1) DE68901014D1 (cs)
DK (1) DK342989A (cs)
ES (1) ES2032681T3 (cs)
GR (1) GR3004148T3 (cs)
ZA (1) ZA894828B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814337A (en) * 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
RU2145219C1 (ru) 1991-05-13 2000-02-10 Дзе Бутс Компани ПЛС Фармацевтическая композиция, содержащая s(-)-2-(4-изобутилфенил)пропионат натрия, способ получения натриевой соли энантиомера 2-(4-изобутилфенил)пропионовой кислоты, s(-)-2-(4-изобутилфенил)пропионат натрия дигидрат
FR2698788B1 (fr) * 1992-12-09 1995-03-03 Union Pharma Scient Appl Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
GB9426196D0 (en) * 1994-12-23 1995-02-22 Procter & Gamble Processes of preparing pharmaceutical compositions
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
ES2142601T3 (es) * 1995-07-31 2000-04-16 Gerhard Gergely Comprimido masticable con accion efervescente.
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US20050176599A1 (en) * 2000-11-09 2005-08-11 Bergquist Catharine J. Controlled delivery system for household products
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
RU2257891C1 (ru) * 2003-12-31 2005-08-10 ООО "Фармстандарт-Фитофарм-НН" Способ получения композиции в форме шипучих таблеток
JP2008509206A (ja) * 2004-08-12 2008-03-27 レキット ベンキーザー ヘルスケア （ユーケイ） リミテッド 溶融押出しにより作製するｎｓａｉｄ及び糖アルコールを含む顆粒
EP1942877A4 (en) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc ORGANOLEPTICALLY ACCEPTABLE IBUPROFEN ORAL DOSAGE FORMULATIONS, METHODS OF PREPARATION AND USE THEREOF
EP1905428A1 (de) * 2006-09-26 2008-04-02 Losan Pharma GmbH Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung
TR200900881A2 (tr) * 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş stabil farmasötik bileşimler
WO2013143688A1 (en) 2012-03-26 2013-10-03 Glatt Ag Taste-masked ibuprofen granules
EP2913049B1 (en) 2014-02-27 2016-11-30 Galenicum Health S.L. Stable pharmaceutical compositions
SI3157506T1 (sl) * 2014-06-20 2021-01-29 Hermes Arzneimittel Gmbh Oralni farmacevtski sestavek z zamaskiranim okusom

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE59106B1 (en) * 1985-05-31 1994-01-12 Warner Lambert Co A therapeutic effervescent composition and a method of preparing the same
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations

Also Published As

Publication number Publication date
CA1336323C (en) 1995-07-18
US5180590A (en) 1993-01-19
ES2032681T3 (es) 1993-02-16
DK342989A (da) 1990-01-13
ATE73656T1 (de) 1992-04-15
DK342989D0 (da) 1989-07-11
JPH07112973B2 (ja) 1995-12-06
EP0351353B1 (en) 1992-03-18
EP0351353A1 (en) 1990-01-17
GR3004148T3 (cs) 1993-03-31
CH677606A5 (cs) 1991-06-14
JPH0272115A (ja) 1990-03-12
DE68901014D1 (de) 1992-04-23

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