ZA888574B - Analgesic - Google Patents

Analgesic

Info

Publication number
ZA888574B
ZA888574B ZA888574A ZA888574A ZA888574B ZA 888574 B ZA888574 B ZA 888574B ZA 888574 A ZA888574 A ZA 888574A ZA 888574 A ZA888574 A ZA 888574A ZA 888574 B ZA888574 B ZA 888574B
Authority
ZA
South Africa
Prior art keywords
alkoxy
alkyl
atoms
contain
alkylthio
Prior art date
Application number
ZA888574A
Other languages
English (en)
Inventor
Peter Raddatz
Raddatz Peter
Wolf-Dietrich Weber
Weber Wolf-Dietrich
Andrew Barber
Barber Andrew
Hans-Peter Wolf
Wolf Hans-Peter
Christoph Seyfried
Seyfried Christoph
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA888574B publication Critical patent/ZA888574B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA888574A 1987-11-16 1988-11-16 Analgesic ZA888574B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873738844 DE3738844A1 (de) 1987-11-16 1987-11-16 Analgetikum

Publications (1)

Publication Number Publication Date
ZA888574B true ZA888574B (en) 1989-08-30

Family

ID=6340578

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA888574A ZA888574B (en) 1987-11-16 1988-11-16 Analgesic

Country Status (15)

Country Link
US (1) US4950648A (fr)
EP (1) EP0316668B1 (fr)
JP (1) JPH01160919A (fr)
KR (1) KR890007741A (fr)
AT (1) ATE89481T1 (fr)
AU (1) AU616695B2 (fr)
CA (1) CA1317549C (fr)
DE (2) DE3738844A1 (fr)
ES (1) ES2069541T3 (fr)
GR (1) GR3007918T3 (fr)
HU (1) HU203199B (fr)
IE (1) IE61301B1 (fr)
PH (1) PH25353A (fr)
PT (1) PT89000B (fr)
ZA (1) ZA888574B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5095019A (en) * 1990-08-27 1992-03-10 Hoechst-Roussel Pharmaceuticals Inc. 4-substituted dihydropyrido(4,3-D)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders
US6166019A (en) * 1998-07-16 2000-12-26 Abbott Laboratories Piperazinyl pyrimidine dione compounds selective for adrenoceptors
AU2001274966A1 (en) * 2000-05-24 2001-12-03 University Of Kentucky Research Foundation Novel long acting, reversible veterinary sedative and analgesic and method of use
FR2832711B1 (fr) 2001-11-26 2004-01-30 Warner Lambert Co Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
AU2004288641B2 (en) * 2003-10-30 2010-08-12 Tioga Pharmaceuticals, Inc. Use of selective opiate receptor modulators in the treatment of neuropathy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB843073A (en) * 1958-05-09 1960-08-04 Toraude Lab 2-methyl-3-orthotolyl-4-quinazolone and acid addition salts thereof
FR1043M (fr) * 1960-12-28 1962-02-09 Soc Ind Fab Antibiotiques Sifa Dérivé de la quinazolone et ses sels, utilisés en thérapeutique.
US3919425A (en) * 1971-04-09 1975-11-11 Miles Lab Method of producing vasodilation using certain 3-substituted-quinazoline derivatives
DE2143117A1 (de) * 1971-08-28 1973-03-08 Troponwerke Dinklage & Co Neue 2-methyl-3-geschweifte klammer auf 3- eckige klammer auf 4-phenylpiperazinyl(1) eckige klammer zu -2-hydroxypropyl geschweifte klammer zu chinazolinon-(4)derivate, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
DE3012837A1 (de) * 1979-04-10 1980-10-30 Sandoz Ag Analgetische und myotonolytische praeparate
US4485107A (en) * 1982-11-01 1984-11-27 Janssen Pharmaceutica N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones
DE3601731A1 (de) * 1986-01-22 1987-07-23 Merck Patent Gmbh Pyrimidinderivate

Also Published As

Publication number Publication date
ATE89481T1 (de) 1993-06-15
AU2510788A (en) 1989-05-18
AU616695B2 (en) 1991-11-07
IE883417L (en) 1989-05-16
HU203199B (en) 1991-06-28
DE3881164D1 (de) 1993-06-24
GR3007918T3 (fr) 1993-08-31
DE3738844A1 (de) 1989-05-24
KR890007741A (ko) 1989-07-05
PT89000B (pt) 1993-02-26
HUT48818A (en) 1989-07-28
CA1317549C (fr) 1993-05-11
ES2069541T3 (es) 1995-05-16
IE61301B1 (en) 1994-10-19
JPH01160919A (ja) 1989-06-23
PH25353A (en) 1991-05-13
EP0316668B1 (fr) 1993-05-19
EP0316668A3 (en) 1990-09-19
US4950648A (en) 1990-08-21
PT89000A (pt) 1988-12-01
EP0316668A2 (fr) 1989-05-24

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