ZA884587B - Castanospermine esters and glycosides - Google Patents

Castanospermine esters and glycosides

Info

Publication number
ZA884587B
ZA884587B ZA884587A ZA884587A ZA884587B ZA 884587 B ZA884587 B ZA 884587B ZA 884587 A ZA884587 A ZA 884587A ZA 884587 A ZA884587 A ZA 884587A ZA 884587 B ZA884587 B ZA 884587B
Authority
ZA
South Africa
Prior art keywords
glycosides
castanospermine esters
castanospermine
esters
Prior art date
Application number
ZA884587A
Other languages
English (en)
Inventor
Paul S Lui
S Lui Paul
John K Daniel
K Daniel John
Barry L Rhinehart
L Rhinehart Barry
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA884587B publication Critical patent/ZA884587B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA884587A 1987-07-02 1988-06-27 Castanospermine esters and glycosides ZA884587B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6935187A 1987-07-02 1987-07-02

Publications (1)

Publication Number Publication Date
ZA884587B true ZA884587B (en) 1989-03-29

Family

ID=22088386

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA884587A ZA884587B (en) 1987-07-02 1988-06-27 Castanospermine esters and glycosides

Country Status (20)

Country Link
EP (1) EP0297534B1 (fi)
JP (1) JP2683915B2 (fi)
KR (1) KR970002636B1 (fi)
CN (2) CN1020609C (fi)
AR (1) AR245128A1 (fi)
AT (1) ATE116318T1 (fi)
AU (1) AU609146B2 (fi)
CA (1) CA1315276C (fi)
DE (1) DE3852579T2 (fi)
DK (1) DK171053B1 (fi)
ES (1) ES2068816T3 (fi)
FI (1) FI87072C (fi)
GR (1) GR3015303T3 (fi)
HU (1) HU199470B (fi)
IE (1) IE65164B1 (fi)
IL (1) IL86928A (fi)
NO (1) NO167664C (fi)
NZ (1) NZ225198A (fi)
PT (1) PT87895B (fi)
ZA (1) ZA884587B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis
US5214050A (en) * 1989-10-17 1993-05-25 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
AU628228B2 (en) * 1989-10-17 1992-09-10 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
US5028614A (en) * 1990-03-30 1991-07-02 Merrell Dow Pharmaceuticals Inc. Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
US5079254A (en) * 1990-06-04 1992-01-07 Merrell Dow Pharmaceuticals Inc. Derivatives of 6-aminooctahydroindolizinetriol
HUP0004095A3 (en) * 1997-05-22 2002-06-28 Aventis Pharmaceuticals Inc Br Process for preparing 6-0-monoesters of castanospermine and salts thereof
GB0110832D0 (en) 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
CN101014341A (zh) * 2004-08-13 2007-08-08 麦根克斯有限公司 治疗或预防嗜肝dna病毒科病毒感染的组合物和方法
DE102020212985B3 (de) 2020-10-14 2021-10-21 Danfoss Power Solutions Gmbh & Co. Ohg Hydraulischer ventilblock sowie hydraulikeinheit für geschlossene kreislaufanwendungen

Also Published As

Publication number Publication date
AR245128A1 (es) 1993-12-30
HU199470B (en) 1990-02-28
CN1027264C (zh) 1995-01-04
PT87895A (pt) 1989-06-30
JPS6479179A (en) 1989-03-24
IE882021L (en) 1989-01-02
EP0297534A2 (en) 1989-01-04
IL86928A (en) 1992-08-18
DK366888A (da) 1989-01-03
EP0297534B1 (en) 1994-12-28
DE3852579D1 (de) 1995-02-09
HUT47572A (en) 1989-03-28
FI87072B (fi) 1992-08-14
KR970002636B1 (ko) 1997-03-07
AU1844888A (en) 1989-01-05
FI87072C (fi) 1992-11-25
DK171053B1 (da) 1996-05-06
NO882940D0 (no) 1988-07-01
ATE116318T1 (de) 1995-01-15
JP2683915B2 (ja) 1997-12-03
ES2068816T3 (es) 1995-05-01
NZ225198A (en) 1989-12-21
FI883164A (fi) 1989-01-03
CN1020609C (zh) 1993-05-12
PT87895B (pt) 1995-03-01
IE65164B1 (en) 1995-10-04
CN1030418A (zh) 1989-01-18
AU609146B2 (en) 1991-04-26
GR3015303T3 (en) 1995-06-30
IL86928A0 (en) 1988-11-30
DE3852579T2 (de) 1995-05-04
CN1065066A (zh) 1992-10-07
KR890002147A (ko) 1989-04-08
NO882940L (no) 1989-01-03
DK366888D0 (da) 1988-07-01
CA1315276C (en) 1993-03-30
EP0297534A3 (en) 1990-01-10
FI883164A0 (fi) 1988-07-01
NO167664B (no) 1991-08-19
NO167664C (no) 1991-11-27

Similar Documents

Publication Publication Date Title
GB2210132B (en) Floodwashing process and floodwasher
JPS6447796A (en) Alkylglucoside and manufacture
GB2210043B (en) Phosphinylcycloalkylcarbonyl and phosphinylcycloalkenylcarbonyl dipeptides
GB2171694B (en) Phenylisopropylamine derivative and its preparation
AR245128A1 (es) Procedimiento para preparar mono- y di-esteres y glicosidos de castanoespermina.
EP0307098A3 (en) Polyalkoxysilylalkylenedisilazanes and silylamines
NZ226450A (en) Crystalline-1-carbacephalosporin and pharmaceutical compositions
EP0155653A3 (en) Substituted (azacycloalk-2-yl) iminophenols and esters thereof
ZA885328B (en) Phenylalkenylcarboxylic acids and their esters
BG51149A3 (en) Conical crusher
GB8629322D0 (en) Cyano-terpenoid esters
HU896405D0 (en) Method and arrangement
EP0411415A3 (en) Polyethercarboxylic esters and their preparation
GB2161478B (en) Citrate esters and methods
JPS6470453A (en) 2-hydroxybenzophenonehydrazide and derivative
AP8700067A0 (en) Fluorebenzyl esters
GB2203631B (en) Cabinets and closures therefor
IL92027A0 (en) Aryloxyaldehydes and their manufacture
ZA897772B (en) Organotinfluorides and their manufacture
ZA875341B (en) Novel phenoxyaliphatylphenyleneoxyalkyl esters and amides
JPS6425789A (en) Substituted amidephophonate and amidephosphate
CS976187A1 (en) Oxigen-bridged tetrahydropyridines- parimidines and hexahydropyridines
IL85664A0 (en) Dicyanoethylaryl derivatives and their preparation
IE860875L (en) Ô-nitrile esters and piperidones
IE852728L (en) Phenylaminoacids and esters