DE3852579D1 - Castanosperminester und Glycoside. - Google Patents

Castanosperminester und Glycoside.

Info

Publication number
DE3852579D1
DE3852579D1 DE3852579T DE3852579T DE3852579D1 DE 3852579 D1 DE3852579 D1 DE 3852579D1 DE 3852579 T DE3852579 T DE 3852579T DE 3852579 T DE3852579 T DE 3852579T DE 3852579 D1 DE3852579 D1 DE 3852579D1
Authority
DE
Germany
Prior art keywords
glycosides
castanospermine esters
castanospermine
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3852579T
Other languages
English (en)
Other versions
DE3852579T2 (de
Inventor
Paul S Liu
John K Daniel
Barry L Rhinehart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE3852579D1 publication Critical patent/DE3852579D1/de
Application granted granted Critical
Publication of DE3852579T2 publication Critical patent/DE3852579T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3852579T 1987-07-02 1988-06-29 Castanosperminester und Glycoside. Expired - Fee Related DE3852579T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6935187A 1987-07-02 1987-07-02

Publications (2)

Publication Number Publication Date
DE3852579D1 true DE3852579D1 (de) 1995-02-09
DE3852579T2 DE3852579T2 (de) 1995-05-04

Family

ID=22088386

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3852579T Expired - Fee Related DE3852579T2 (de) 1987-07-02 1988-06-29 Castanosperminester und Glycoside.

Country Status (20)

Country Link
EP (1) EP0297534B1 (de)
JP (1) JP2683915B2 (de)
KR (1) KR970002636B1 (de)
CN (2) CN1020609C (de)
AR (1) AR245128A1 (de)
AT (1) ATE116318T1 (de)
AU (1) AU609146B2 (de)
CA (1) CA1315276C (de)
DE (1) DE3852579T2 (de)
DK (1) DK171053B1 (de)
ES (1) ES2068816T3 (de)
FI (1) FI87072C (de)
GR (1) GR3015303T3 (de)
HU (1) HU199470B (de)
IE (1) IE65164B1 (de)
IL (1) IL86928A (de)
NO (1) NO167664C (de)
NZ (1) NZ225198A (de)
PT (1) PT87895B (de)
ZA (1) ZA884587B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis
US5214050A (en) * 1989-10-17 1993-05-25 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
ZA908134B (en) * 1989-10-17 1991-07-31 Merrell Dow Pharma Esters of castanosperime in the treatment of cerebral malaria
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
US5028614A (en) * 1990-03-30 1991-07-02 Merrell Dow Pharmaceuticals Inc. Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
US5079254A (en) * 1990-06-04 1992-01-07 Merrell Dow Pharmaceuticals Inc. Derivatives of 6-aminooctahydroindolizinetriol
DK0983270T3 (da) * 1997-05-22 2004-05-10 Aventis Pharma Inc Fremgangsmåde til fremstilling af 6-O-monoestere af castanospermin
GB0110832D0 (en) 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
CA2576425A1 (en) * 2004-08-13 2006-08-17 Migenix Inc. Compositions and methods for treating or preventing hepadnaviridae infection
DE102020212985B3 (de) 2020-10-14 2021-10-21 Danfoss Power Solutions Gmbh & Co. Ohg Hydraulischer ventilblock sowie hydraulikeinheit für geschlossene kreislaufanwendungen

Also Published As

Publication number Publication date
DK366888A (da) 1989-01-03
NO167664C (no) 1991-11-27
JPS6479179A (en) 1989-03-24
GR3015303T3 (en) 1995-06-30
JP2683915B2 (ja) 1997-12-03
NO167664B (no) 1991-08-19
FI87072C (fi) 1992-11-25
CN1027264C (zh) 1995-01-04
FI883164A0 (fi) 1988-07-01
IE65164B1 (en) 1995-10-04
KR890002147A (ko) 1989-04-08
ATE116318T1 (de) 1995-01-15
NO882940L (no) 1989-01-03
CA1315276C (en) 1993-03-30
IL86928A (en) 1992-08-18
DK366888D0 (da) 1988-07-01
EP0297534A2 (de) 1989-01-04
AU609146B2 (en) 1991-04-26
EP0297534A3 (en) 1990-01-10
HU199470B (en) 1990-02-28
PT87895B (pt) 1995-03-01
KR970002636B1 (ko) 1997-03-07
AU1844888A (en) 1989-01-05
DE3852579T2 (de) 1995-05-04
DK171053B1 (da) 1996-05-06
ES2068816T3 (es) 1995-05-01
IL86928A0 (en) 1988-11-30
CN1065066A (zh) 1992-10-07
EP0297534B1 (de) 1994-12-28
FI87072B (fi) 1992-08-14
FI883164A (fi) 1989-01-03
CN1030418A (zh) 1989-01-18
IE882021L (en) 1989-01-02
HUT47572A (en) 1989-03-28
ZA884587B (en) 1989-03-29
AR245128A1 (es) 1993-12-30
CN1020609C (zh) 1993-05-12
PT87895A (pt) 1989-06-30
NZ225198A (en) 1989-12-21
NO882940D0 (no) 1988-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERRELL PHARMACEUTICALS INC. (N.D.GES.D. STAATES D

8339 Ceased/non-payment of the annual fee