ZA881109B - Human interleukin-3 and muteins thereof - Google Patents

Human interleukin-3 and muteins thereof

Info

Publication number
ZA881109B
ZA881109B ZA881109A ZA881109A ZA881109B ZA 881109 B ZA881109 B ZA 881109B ZA 881109 A ZA881109 A ZA 881109A ZA 881109 A ZA881109 A ZA 881109A ZA 881109 B ZA881109 B ZA 881109B
Authority
ZA
South Africa
Prior art keywords
muteins
human interleukin
interleukin
human
Prior art date
Application number
ZA881109A
Other languages
English (en)
Inventor
Otsuka Takeshi
Original Assignee
Schering Biotech Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corporation filed Critical Schering Biotech Corporation
Publication of ZA881109B publication Critical patent/ZA881109B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
ZA881109A 1987-02-18 1988-02-17 Human interleukin-3 and muteins thereof ZA881109B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1607987A 1987-02-18 1987-02-18

Publications (1)

Publication Number Publication Date
ZA881109B true ZA881109B (en) 1988-08-17

Family

ID=21775278

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881109A ZA881109B (en) 1987-02-18 1988-02-17 Human interleukin-3 and muteins thereof

Country Status (16)

Country Link
EP (2) EP0355093A1 (xx)
JP (1) JPH02500328A (xx)
KR (1) KR890700608A (xx)
CN (1) CN88100685A (xx)
AR (1) AR243240A1 (xx)
AU (1) AU626789B2 (xx)
FI (1) FI893872A (xx)
HU (1) HU204890B (xx)
IL (1) IL85444A0 (xx)
MY (1) MY102806A (xx)
NZ (1) NZ223551A (xx)
OA (1) OA09736A (xx)
PT (1) PT86772B (xx)
TN (1) TNSN88013A1 (xx)
WO (1) WO1988006161A1 (xx)
ZA (1) ZA881109B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
AU1496688A (en) * 1987-01-20 1988-08-10 Immunex Corporation Human interleukin-3 proteins
US5304637A (en) * 1987-07-13 1994-04-19 Gist-Brocades N.V. Expression and purification of human interleukin-3 and muteins thereof
US6384194B1 (en) 1987-12-16 2002-05-07 Dsm N.V. Expression and purification of human interleukin-3 and muteins thereof
EP0425536A4 (en) * 1988-07-20 1992-01-02 Immunex Corporation Nonglycosylated human interleukin-3 compositions
US5128450A (en) * 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
ES2106017T3 (es) * 1989-08-14 1997-11-01 Gist Brocades Nv Mutantes de interleucina-3 humana.
US5516512A (en) * 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
US5108910A (en) * 1989-08-22 1992-04-28 Immunex Corporation DNA sequences encoding fusion proteins comprising GM-CSF and IL-3
JP3115318B2 (ja) * 1989-08-22 2000-12-04 イミュネックス・コーポレーション Ｇｍ―ｃｓｆ及びｉｌ―３を含む融合タンパク質
US5073627A (en) * 1989-08-22 1991-12-17 Immunex Corporation Fusion proteins comprising GM-CSF and IL-3
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
AU668364B2 (en) * 1991-10-07 1996-05-02 Medvet Science Pty. Ltd. Human IL-3 variants
US5376367A (en) * 1991-11-22 1994-12-27 Immunex Corporation Fusion proteins comprising MGF and IL-3
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6153183A (en) * 1992-11-24 2000-11-28 G. D. Searle & Company Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US6403076B1 (en) 1992-11-24 2002-06-11 S. Christopher Bauer Compositions for increasing hematopoiesis with interleukin-3 mutants
US6361976B1 (en) 1992-11-24 2002-03-26 S. Christopher Bauer Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
EP0672145B1 (en) 1992-11-24 2003-04-23 G.D. Searle & Co. Interleukin-3 (il-3) multiple mutation polypeptides
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
RO120579B1 (ro) 1995-10-04 2006-04-28 Immunex Corporation Utilizarea ligandului flt3
US6670323B1 (en) 1999-11-12 2003-12-30 Baxter International, Inc. Reduced side-effect hemoglobin compositions
WO2006079169A1 (en) * 2005-01-25 2006-08-03 Apollo Life Sciences Limited Parameter selected gm-csf, il-3, il-4, il-5 and chimeras thereof for therapeutic and diagnostic purposes
EA033803B1 (ru) 2012-02-07 2019-11-27 Global Bio Therapeutics Inc Способ доставки нуклеиновых кислот с разделением, их композиции и использование
EP3030163B1 (en) 2013-08-08 2019-03-20 Global Bio Therapeutics, Inc. Clamp device for minimally invasive procedures
CN112195177B (zh) * 2020-10-28 2021-08-06 上海慕柏生物医学科技有限公司 一种核酸提取方法及试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60207594A (ja) * 1984-03-30 1985-10-19 Ajinomoto Co Inc ヒトインタ−ロイキン３の製造方法
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
WO1988004691A1 (en) * 1986-12-16 1988-06-30 Gist-Brocades N.V. Molecular cloning and expression of human il-3

Also Published As

Publication number Publication date
AU1429488A (en) 1988-09-14
KR890700608A (ko) 1989-04-26
PT86772B (pt) 1992-05-29
EP0355093A1 (en) 1990-02-28
AU626789B2 (en) 1992-08-13
WO1988006161A1 (en) 1988-08-25
OA09736A (en) 1993-11-30
CN88100685A (zh) 1988-12-14
JPH02500328A (ja) 1990-02-08
MY102806A (en) 1992-11-30
FI893872A0 (fi) 1989-08-17
TNSN88013A1 (fr) 1990-07-10
PT86772A (pt) 1988-03-01
HUT50872A (en) 1990-03-28
EP0282185A1 (en) 1988-09-14
FI893872A (fi) 1989-08-17
NZ223551A (en) 1991-02-26
IL85444A0 (en) 1988-07-31
HU204890B (en) 1992-02-28
AR243240A1 (es) 1993-07-30

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