PT86772A - Process for preparing human interleukin-3 and muteins thereof - Google Patents

Process for preparing human interleukin-3 and muteins thereof

Info

Publication number
PT86772A
PT86772A PT86772A PT8677288A PT86772A PT 86772 A PT86772 A PT 86772A PT 86772 A PT86772 A PT 86772A PT 8677288 A PT8677288 A PT 8677288A PT 86772 A PT86772 A PT 86772A
Authority
PT
Portugal
Prior art keywords
muteins
human interleukin
preparing human
preparing
interleukin
Prior art date
Application number
PT86772A
Other languages
English (en)
Other versions
PT86772B (pt
Inventor
Takeshi Otsuka
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of PT86772A publication Critical patent/PT86772A/pt
Publication of PT86772B publication Critical patent/PT86772B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT86772A 1987-02-18 1988-02-17 Processo para a preparacao de interleuquina-3 humana e de suas muteinas PT86772B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1607987A 1987-02-18 1987-02-18

Publications (2)

Publication Number Publication Date
PT86772A true PT86772A (pt) 1988-03-01
PT86772B PT86772B (pt) 1992-05-29

Family

ID=21775278

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86772A PT86772B (pt) 1987-02-18 1988-02-17 Processo para a preparacao de interleuquina-3 humana e de suas muteinas

Country Status (16)

Country Link
EP (2) EP0282185A1 (pt)
JP (1) JPH02500328A (pt)
KR (1) KR890700608A (pt)
CN (1) CN88100685A (pt)
AR (1) AR243240A1 (pt)
AU (1) AU626789B2 (pt)
FI (1) FI893872A (pt)
HU (1) HU204890B (pt)
IL (1) IL85444A0 (pt)
MY (1) MY102806A (pt)
NZ (1) NZ223551A (pt)
OA (1) OA09736A (pt)
PT (1) PT86772B (pt)
TN (1) TNSN88013A1 (pt)
WO (1) WO1988006161A1 (pt)
ZA (1) ZA881109B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
EP0342206A4 (en) * 1987-01-20 1990-09-19 Immunex Corporation Human interleukin-3 proteins
US5304637A (en) * 1987-07-13 1994-04-19 Gist-Brocades N.V. Expression and purification of human interleukin-3 and muteins thereof
US6384194B1 (en) 1987-12-16 2002-05-07 Dsm N.V. Expression and purification of human interleukin-3 and muteins thereof
JPH04500508A (ja) * 1988-07-20 1992-01-30 イミュネックス・コーポレーション 非グリコシル化　ヒト　インターロイキン―３　組成物
US5128450A (en) * 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
US5516512A (en) 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
ES2106017T3 (es) * 1989-08-14 1997-11-01 Gist Brocades Nv Mutantes de interleucina-3 humana.
EP0489116B1 (en) * 1989-08-22 1994-04-06 Immunex Corporation Fusion proteins comprising gm-csf and il-3
US5073627A (en) * 1989-08-22 1991-12-17 Immunex Corporation Fusion proteins comprising GM-CSF and IL-3
US5108910A (en) * 1989-08-22 1992-04-28 Immunex Corporation DNA sequences encoding fusion proteins comprising GM-CSF and IL-3
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
ATE179211T1 (de) * 1991-10-07 1999-05-15 Medvet Science Pty Ltd Menschliche il-3-varianten
US5376367A (en) * 1991-11-22 1994-12-27 Immunex Corporation Fusion proteins comprising MGF and IL-3
US6361976B1 (en) 1992-11-24 2002-03-26 S. Christopher Bauer Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
US6153183A (en) * 1992-11-24 2000-11-28 G. D. Searle & Company Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
DK0672145T3 (da) * 1992-11-24 2003-08-11 Searle & Co Interleukin-3-(IL-3)-polypeptider med flere mutationer
US6403076B1 (en) 1992-11-24 2002-06-11 S. Christopher Bauer Compositions for increasing hematopoiesis with interleukin-3 mutants
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
EA199800272A1 (ru) 1995-10-04 1998-10-29 Иммунекс Корпорейшн Фактор, стимулирующий дендритные клетки
AU784195B2 (en) 1999-11-12 2006-02-16 Baxter Biotech Technology S.A.R.L. Reduced side-effect hemoglobin compositions
EP1848738A1 (en) * 2005-01-25 2007-10-31 Apollo Life Sciences Limited Parameter selected gm-csf, il-3, il-4, il-5 and chimeras thereof for therapeutic and diagnostic purposes
CN107982548A (zh) 2012-02-07 2018-05-04 全球生物疗法有限公司 核酸输送的区室化方法及其组合物和应用
CA2920261C (en) 2013-08-08 2018-04-03 Global Bio Therapeutics, Inc. Clamp device for minimally invasive procedures and uses thereof
CN112195177B (zh) * 2020-10-28 2021-08-06 上海慕柏生物医学科技有限公司 一种核酸提取方法及试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60207594A (ja) * 1984-03-30 1985-10-19 Ajinomoto Co Inc ヒトインタ−ロイキン３の製造方法
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
ATE161882T1 (de) * 1986-12-16 1998-01-15 Gist Brocades Nv Molekulare klonierung und expression von menschlichem il-3

Also Published As

Publication number Publication date
AR243240A1 (es) 1993-07-30
FI893872A0 (fi) 1989-08-17
HUT50872A (en) 1990-03-28
CN88100685A (zh) 1988-12-14
EP0355093A1 (en) 1990-02-28
OA09736A (en) 1993-11-30
MY102806A (en) 1992-11-30
AU1429488A (en) 1988-09-14
TNSN88013A1 (fr) 1990-07-10
AU626789B2 (en) 1992-08-13
WO1988006161A1 (en) 1988-08-25
IL85444A0 (en) 1988-07-31
KR890700608A (ko) 1989-04-26
ZA881109B (en) 1988-08-17
EP0282185A1 (en) 1988-09-14
FI893872A (fi) 1989-08-17
JPH02500328A (ja) 1990-02-08
NZ223551A (en) 1991-02-26
PT86772B (pt) 1992-05-29
HU204890B (en) 1992-02-28

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911118

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950531