ZA876434B - Dihydropyridine compounds,processes for their preparation and their use - Google Patents

Dihydropyridine compounds,processes for their preparation and their use

Info

Publication number
ZA876434B
ZA876434B ZA876434A ZA876434A ZA876434B ZA 876434 B ZA876434 B ZA 876434B ZA 876434 A ZA876434 A ZA 876434A ZA 876434 A ZA876434 A ZA 876434A ZA 876434 B ZA876434 B ZA 876434B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
alkyl
chain
halogen
hydroxyl
Prior art date
Application number
ZA876434A
Other languages
English (en)
Inventor
Siegfried Goldmann
Goldmann Siegfried
Hans-Juergen Ahr
Ahr Hans-Juergen
Walter Puls
Puls Walter
Hilmar Bischoff
Bischoff Hilmar
Dieter Petzinna
Petzinna Dieter
Klaus Schlossmann
Schlossmann Klaus
Joachim Bender
Bender Joachim
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA876434B publication Critical patent/ZA876434B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA876434A 1986-08-30 1987-08-28 Dihydropyridine compounds,processes for their preparation and their use ZA876434B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863629545 DE3629545A1 (de) 1986-08-30 1986-08-30 Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ZA876434B true ZA876434B (en) 1988-05-25

Family

ID=6308550

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876434A ZA876434B (en) 1986-08-30 1987-08-28 Dihydropyridine compounds,processes for their preparation and their use

Country Status (18)

Country Link
US (1) US4786641A (fi)
EP (1) EP0258729B1 (fi)
JP (1) JPH0832685B2 (fi)
KR (1) KR880002874A (fi)
CN (1) CN87105876A (fi)
AT (1) ATE52250T1 (fi)
AU (1) AU602529B2 (fi)
CA (1) CA1300626C (fi)
DD (1) DD263985A5 (fi)
DE (2) DE3629545A1 (fi)
DK (1) DK452687A (fi)
ES (1) ES2014456B3 (fi)
FI (1) FI873726A (fi)
GR (1) GR3000447T3 (fi)
HU (1) HU199120B (fi)
IL (1) IL83661A0 (fi)
PT (1) PT85622B (fi)
ZA (1) ZA876434B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0657432B1 (de) 1993-12-10 2003-03-12 Bayer Ag Phenyl-substituierte 1,4-Dihydropyridine mit cerebraler Aktivität
DE4430092A1 (de) * 1994-08-25 1996-02-29 Bayer Ag 2,3-Cyclisch kondensierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JPH11106375A (ja) * 1997-08-18 1999-04-20 Pfizer Pharmaceut Inc ブラジキニンアンタゴニストとしての光学的に活性な１，４−ジヒドロピリジン化合物
US6711297B1 (en) * 1998-07-03 2004-03-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and apparatus for dynamic transfer of image data
CO5271699A1 (es) 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205165D0 (en) * 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0318464D0 (en) * 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0318463D0 (en) * 2003-08-07 2003-09-10 Astrazeneca Ab Chemical compounds
GB0319759D0 (en) * 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
GB0319690D0 (en) * 2003-08-22 2003-09-24 Astrazeneca Ab Chemical compounds
WO2005025507A2 (en) * 2003-09-10 2005-03-24 Synta Phamaceuticals Corp. Dihydropyridine compounds for treating or preventing metabolic disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB125803A (en) * 1918-05-29 1919-05-01 Joseph Ernest Barrows Improvements in Sparking Plugs for use with Internal Combustion Engines.
GB161221A (en) * 1919-11-21 1921-03-21 Edwin William Nick Improved method of feed-water regulation for marine boilers and means therefor
GB158138A (en) * 1919-11-25 1921-02-03 Herman Schoener Improvements in weed cutters or hoes
DE2248150A1 (de) * 1972-09-30 1974-04-04 Bayer Ag Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3970662A (en) * 1975-06-19 1976-07-20 Sterling Drug Inc. 4-(3-Nitrophenyl)-2,3,5,6-pyridinetetracarboxylic acid and intermediates
EP0125803A3 (en) * 1983-04-27 1987-01-21 FISONS plc Pharmaceutically active dihydropyridines
DE3445356A1 (de) * 1983-12-15 1985-06-27 Ciba-Geigy Ag, Basel Halogenierte thiophen-verbindungen
DE3410645A1 (de) * 1984-03-23 1985-09-26 Bayer Ag, 5090 Leverkusen L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US4748244A (en) * 1984-05-11 1988-05-31 Ciba-Geigy Corporation Process for the preparation of pyridine-2-3-dicarboxylic acid derivatives, and novel 1-amino-1,4-dihydropyridine-2-3-diarboxylic acid derivatives

Also Published As

Publication number Publication date
PT85622A (en) 1987-09-01
KR880002874A (ko) 1988-05-12
EP0258729B1 (de) 1990-04-25
IL83661A0 (en) 1988-01-31
JPH0832685B2 (ja) 1996-03-29
US4786641A (en) 1988-11-22
DE3629545A1 (de) 1988-03-10
DE3762416D1 (de) 1990-05-31
CN87105876A (zh) 1988-03-23
GR3000447T3 (en) 1991-06-28
DD263985A5 (de) 1989-01-18
EP0258729A3 (en) 1988-06-15
EP0258729A2 (de) 1988-03-09
ATE52250T1 (de) 1990-05-15
HUT45014A (en) 1988-05-30
CA1300626C (en) 1992-05-12
DK452687A (da) 1988-03-01
JPS6372674A (ja) 1988-04-02
PT85622B (pt) 1990-05-31
FI873726A (fi) 1988-03-01
AU602529B2 (en) 1990-10-18
AU7769587A (en) 1988-03-03
ES2014456B3 (es) 1990-07-16
DK452687D0 (da) 1987-08-28
FI873726A0 (fi) 1987-08-27
HU199120B (en) 1990-01-29

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