ZA867417B - N-alkylation of dihydrolysergic acid - Google Patents
N-alkylation of dihydrolysergic acidInfo
- Publication number
- ZA867417B ZA867417B ZA867417A ZA867417A ZA867417B ZA 867417 B ZA867417 B ZA 867417B ZA 867417 A ZA867417 A ZA 867417A ZA 867417 A ZA867417 A ZA 867417A ZA 867417 B ZA867417 B ZA 867417B
- Authority
- ZA
- South Africa
- Prior art keywords
- sub
- alkylation
- dihydrolysergic acid
- sup
- cycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/782,339 US4734501A (en) | 1985-10-01 | 1985-10-01 | N-alkylation of dihydrolysergic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA867417B true ZA867417B (en) | 1988-04-27 |
Family
ID=25125737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA867417A ZA867417B (en) | 1985-10-01 | 1986-09-29 | N-alkylation of dihydrolysergic acid |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4734501A (pt) |
| EP (1) | EP0219256B1 (pt) |
| JP (1) | JPH0670049B2 (pt) |
| KR (1) | KR870001680B1 (pt) |
| CN (1) | CN1013446B (pt) |
| AT (1) | ATE62483T1 (pt) |
| AU (1) | AU578169B2 (pt) |
| CA (1) | CA1296323C (pt) |
| DE (1) | DE3678665D1 (pt) |
| DK (1) | DK170044B1 (pt) |
| EG (1) | EG17902A (pt) |
| ES (1) | ES2002393A6 (pt) |
| GR (1) | GR862463B (pt) |
| HK (1) | HK24192A (pt) |
| HU (1) | HU196396B (pt) |
| IE (1) | IE58690B1 (pt) |
| IL (1) | IL80194A (pt) |
| NZ (1) | NZ217721A (pt) |
| PH (1) | PH23030A (pt) |
| PT (1) | PT83449B (pt) |
| SU (1) | SU1486062A3 (pt) |
| ZA (1) | ZA867417B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2584719B1 (fr) * | 1985-07-11 | 1987-10-02 | Rhone Poulenc Sante | Procede de preparation des derives n-methyles du lysergol et du methoxy-10a lumilysergol |
| US4968802A (en) * | 1985-10-01 | 1990-11-06 | Eli Lilly And Company | Process of making alkoxy cycloalkanol esters of dihydrolysergic acid |
| US4906639A (en) * | 1985-10-01 | 1990-03-06 | Eli Lilly And Company | Cycloalkanol esters of dihydrolysergic acid |
| GR862466B (en) * | 1985-10-01 | 1987-02-02 | Lilly Co Eli | Esters of dihydrolysergic acid |
| US4845224A (en) * | 1985-10-01 | 1989-07-04 | Eli Lilly And Company | Cycloalkanol esters of dihydrolysergic acid having peripheral serotonin antagonist properties |
| US4914107A (en) * | 1989-01-17 | 1990-04-03 | Eli Lilly And Company | Method for selectively blocking 5-HT2 receptors |
| US5441961A (en) * | 1992-08-27 | 1995-08-15 | Eli Lilly And Company | Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines |
| WO2004087637A1 (en) * | 2003-03-31 | 2004-10-14 | Takasago International Corporation | Production of n-alkylamide compounds |
| CN102775402B (zh) * | 2011-05-13 | 2015-08-26 | 上海现代制药股份有限公司 | 一种制备二氢麦角酸的中间体及其制备方法 |
| RU2615949C1 (ru) * | 2015-11-18 | 2017-04-11 | Федеральное государственное казенное образовательное учреждение высшего профессионального образования "Калининградский пограничный институт Федеральной службы безопасности Российской Федерации" | Способ сигнализационного прикрытия т-образного перекрестка дорог |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1095296A (pt) * | 1900-01-01 | |||
| US3183234A (en) * | 1963-11-21 | 1965-05-11 | Lilly Co Eli | Octahydroindoloquinolines |
| US3580916A (en) * | 1969-02-20 | 1971-05-25 | Lilly Co Eli | Hydroxyesters of hexa- and octahydroindoloquinolines |
| YU40004B (en) * | 1977-07-21 | 1985-06-30 | Lek Tovarna Farmacevtskih | Praocess for preparing n-substituted esters of 9,10-dihydrlysergic acid |
| DE3304361A1 (de) * | 1982-02-17 | 1983-08-25 | Sandoz-Patent-GmbH, 7850 Lörrach | Mutterkornalkaloide, verfahren zu deren herstellung sowie diese verbindungen enthaltende pharmazeutische zusammensetzungen |
| GR862466B (en) * | 1985-10-01 | 1987-02-02 | Lilly Co Eli | Esters of dihydrolysergic acid |
-
1985
- 1985-10-01 US US06/782,339 patent/US4734501A/en not_active Expired - Lifetime
-
1986
- 1986-09-29 EP EP86307442A patent/EP0219256B1/en not_active Expired - Lifetime
- 1986-09-29 PT PT83449A patent/PT83449B/pt not_active IP Right Cessation
- 1986-09-29 ZA ZA867417A patent/ZA867417B/xx unknown
- 1986-09-29 AU AU63209/86A patent/AU578169B2/en not_active Ceased
- 1986-09-29 EG EG610/86A patent/EG17902A/xx active
- 1986-09-29 GR GR862463A patent/GR862463B/el unknown
- 1986-09-29 CA CA000519289A patent/CA1296323C/en not_active Expired - Lifetime
- 1986-09-29 IL IL80194A patent/IL80194A/xx not_active IP Right Cessation
- 1986-09-29 NZ NZ217721A patent/NZ217721A/xx unknown
- 1986-09-29 AT AT86307442T patent/ATE62483T1/de active
- 1986-09-29 DE DE8686307442T patent/DE3678665D1/de not_active Expired - Lifetime
- 1986-09-29 PH PH34317A patent/PH23030A/en unknown
- 1986-09-30 JP JP61234255A patent/JPH0670049B2/ja not_active Expired - Lifetime
- 1986-09-30 SU SU864028225A patent/SU1486062A3/ru active
- 1986-09-30 KR KR1019860008206A patent/KR870001680B1/ko not_active IP Right Cessation
- 1986-09-30 CN CN86106720A patent/CN1013446B/zh not_active Expired
- 1986-09-30 IE IE258786A patent/IE58690B1/en not_active IP Right Cessation
- 1986-09-30 ES ES8602321A patent/ES2002393A6/es not_active Expired
- 1986-09-30 DK DK466786A patent/DK170044B1/da not_active IP Right Cessation
- 1986-09-30 HU HU864145A patent/HU196396B/hu not_active IP Right Cessation
-
1992
- 1992-04-02 HK HK241/92A patent/HK24192A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PH23030A (en) | 1989-03-10 |
| DK466786D0 (da) | 1986-09-30 |
| EP0219256B1 (en) | 1991-04-10 |
| KR870001680B1 (ko) | 1987-09-22 |
| PT83449B (pt) | 1989-05-12 |
| JPH0670049B2 (ja) | 1994-09-07 |
| KR870004027A (ko) | 1987-05-07 |
| JPS6284083A (ja) | 1987-04-17 |
| IL80194A (en) | 1990-12-23 |
| EP0219256A1 (en) | 1987-04-22 |
| HU196396B (en) | 1988-11-28 |
| ES2002393A6 (es) | 1988-08-01 |
| AU6320986A (en) | 1987-04-02 |
| SU1486062A3 (ru) | 1989-06-07 |
| GR862463B (pt) | 1987-02-02 |
| HUT41779A (en) | 1987-05-28 |
| CN86106720A (zh) | 1987-04-01 |
| AU578169B2 (en) | 1988-10-13 |
| CA1296323C (en) | 1992-02-25 |
| DK170044B1 (da) | 1995-05-08 |
| EG17902A (en) | 1991-03-30 |
| NZ217721A (en) | 1989-02-24 |
| IE58690B1 (en) | 1993-11-03 |
| PT83449A (en) | 1986-10-01 |
| DK466786A (da) | 1987-04-02 |
| US4734501A (en) | 1988-03-29 |
| IE862587L (en) | 1987-04-01 |
| DE3678665D1 (de) | 1991-05-16 |
| IL80194A0 (en) | 1986-12-31 |
| HK24192A (en) | 1992-04-10 |
| CN1013446B (zh) | 1991-08-07 |
| ATE62483T1 (de) | 1991-04-15 |
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