ES2003299A6 - Procedimiento de preparacion de derivados triazinas asimetricos condensados y de isomeros de los mismos - Google Patents

Procedimiento de preparacion de derivados triazinas asimetricos condensados y de isomeros de los mismos

Info

Publication number
ES2003299A6
ES2003299A6 ES8701359A ES8701359A ES2003299A6 ES 2003299 A6 ES2003299 A6 ES 2003299A6 ES 8701359 A ES8701359 A ES 8701359A ES 8701359 A ES8701359 A ES 8701359A ES 2003299 A6 ES2003299 A6 ES 2003299A6
Authority
ES
Spain
Prior art keywords
image
formula
condensed
preparation
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701359A
Other languages
English (en)
Inventor
Sandor Batori
Gyorgy Hajos
Andras Messmer
Pal Benko
Laszlo Pallos
Lujza Petocz
Katalin Grasser
Ibolya Kosoczky
Eniko Szirt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2003299A6 publication Critical patent/ES2003299A6/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA INVENCION SE RELACIONA CON UN PROCEDIMIENTO DE PREPARACION DE DERIVADOS TRIAZINAS ASIMETRICOS CONDENSADOS DE FORMULA GENERAL I E ISOMEROS DE ELLOS, EN CUYA FORMULA: R1 REPRESENTA ALQUILO C1©10, FENILO O NAFTILO, CUYOS DOS ULTIMOS GRUPOS PUEDEN INCLUIR OPTATIVAMENTE UNO O MAS SUSTITUYENTES ALOGENOS, NITROS, AMINOS, HIDROXILOS, ALQUILOS C1©4 Y/O ALCOXILOS C1©4 IDENTICOS O DIFERENTES; R2 REPRESENTA HIDROGENO, HALOGENO, HIDROXILO, ALQUILO C1©4, FENILO O NAFTILO, CUYOS DOS ULTIMOS GRUPOS PUEDEN INCLUIR OPTATIVAMENTE UNO O MAS SUSTITUYENTES HALOGENOS, NITROS, AMINOS, HIDROXILOS, ALQUILOS C1©4 Y/O ALCOXILOS C1©4 IDENTICOS O DIFERENTES; R3 REPRESENTA HIDROGENO O ALQUILO C1©4; Z3 REPRESENTA UN GRUPO DE FORMULA (A) O (B). ESTOS COMPUESTOS SE OBTIENEN DE DERIVADOS OXO, EN REACCION CON HIDROXILAMINAS, IMIDAS O ACILIMIDAS, INCLUYENDO UNA CICLACION. LOS COMPUESTOS ASI OBTENIDOS SON DERIVADOS CONOCIDOS CON ACTIVIDAD FARMACEUTICA. LA VENTAJA DEL PROCEDIMIENTO FRENTE A OTROS DESCRITOS CONSISTE EN SU MENOR NUMERO DE PASOS DE SINTESIS, ASI COMO DE UN MEJOR RENDIMIENTO.
ES8701359A 1986-05-06 1987-05-06 Procedimiento de preparacion de derivados triazinas asimetricos condensados y de isomeros de los mismos Expired ES2003299A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU861857A HU199464B (en) 1986-05-06 1986-05-06 Process for producing condensed cis-triazine derivatives

Publications (1)

Publication Number Publication Date
ES2003299A6 true ES2003299A6 (es) 1988-10-16

Family

ID=10956545

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701359A Expired ES2003299A6 (es) 1986-05-06 1987-05-06 Procedimiento de preparacion de derivados triazinas asimetricos condensados y de isomeros de los mismos

Country Status (18)

Country Link
US (1) US4871846A (es)
JP (1) JPS62273978A (es)
AT (1) AT392641B (es)
BE (1) BE1002101A4 (es)
CH (1) CH673282A5 (es)
DD (1) DD264437A5 (es)
DE (1) DE3715076A1 (es)
DK (1) DK229087A (es)
ES (1) ES2003299A6 (es)
FR (1) FR2598418B1 (es)
GB (1) GB2190673B (es)
HU (1) HU199464B (es)
IL (1) IL82435A (es)
IT (1) IT1204992B (es)
NL (1) NL8701043A (es)
PL (1) PL265518A1 (es)
SE (1) SE8701861L (es)
YU (2) YU80487A (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU187305B (en) * 1980-07-18 1985-12-28 Egyt Gyogyszervegyeszeti Gyar Process for producing condensed as-triazine derivatives
DE3434597A1 (de) * 1983-09-20 1985-04-18 Egyt Gyógyszervegyészeti Gyár, Budapest Neue kondensierte as-triazinium-derivate, ein verfahren zur herstellung derselben und diese verbindungen enthaltende pharmazeutische mittel
HU190503B (en) * 1983-09-20 1986-09-29 Egyt Gyogyszervegyeszetei Gyar,Hu Process for production of condensated as-triazine derivatives
HU190504B (en) * 1983-09-20 1986-09-29 Egis Gyogyszergyar,Hu Process for preparing condensed as-triazinium-derivatives
HU190505B (en) * 1983-09-20 1986-09-29 Egis Gyogyszergyar,Hu Process for preparing condensed as-triazine-derivatives of twin ion type

Also Published As

Publication number Publication date
GB2190673B (en) 1990-05-16
CH673282A5 (es) 1990-02-28
IT8720402A0 (it) 1987-05-06
FR2598418A1 (fr) 1987-11-13
GB2190673A (en) 1987-11-25
DE3715076A1 (de) 1987-11-19
DK229087D0 (da) 1987-05-05
GB8710697D0 (en) 1987-06-10
IT1204992B (it) 1989-03-10
YU69588A (en) 1989-08-31
AT392641B (de) 1991-05-10
NL8701043A (nl) 1987-12-01
US4871846A (en) 1989-10-03
PL265518A1 (en) 1988-07-21
FR2598418B1 (fr) 1990-11-02
ATA113287A (de) 1990-10-15
IL82435A0 (en) 1987-11-30
JPS62273978A (ja) 1987-11-28
SE8701861L (sv) 1987-11-07
YU80487A (en) 1988-12-31
DD264437A5 (de) 1989-02-01
HUT44030A (en) 1988-01-28
IL82435A (en) 1991-07-18
DK229087A (da) 1987-11-07
BE1002101A4 (fr) 1990-07-03
SE8701861D0 (sv) 1987-05-06
HU199464B (en) 1990-02-28

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-05-06

FD1A Patent lapsed

Effective date: 19990405