ZA864833B - New phenylacetic acid derivatives,pharmaceutical compositions containing these compounds and processes for preparing them - Google Patents

New phenylacetic acid derivatives,pharmaceutical compositions containing these compounds and processes for preparing them

Info

Publication number
ZA864833B
ZA864833B ZA864833A ZA864833A ZA864833B ZA 864833 B ZA864833 B ZA 864833B ZA 864833 A ZA864833 A ZA 864833A ZA 864833 A ZA864833 A ZA 864833A ZA 864833 B ZA864833 B ZA 864833B
Authority
ZA
South Africa
Prior art keywords
group
carbon atoms
piperidino
acid derivatives
phenylacetic acid
Prior art date
Application number
ZA864833A
Other languages
English (en)
Inventor
Wolfgang Grell
Rudolf Hurnaus
Robert Sauter
Manfred Reiffen
Eckhard Rupprecht
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA864833B publication Critical patent/ZA864833B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA864833A 1985-07-01 1986-06-30 New phenylacetic acid derivatives,pharmaceutical compositions containing these compounds and processes for preparing them ZA864833B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853523466 DE3523466A1 (de) 1985-07-01 1985-07-01 Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA864833B true ZA864833B (en) 1988-03-30

Family

ID=6274655

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA864833A ZA864833B (en) 1985-07-01 1986-06-30 New phenylacetic acid derivatives,pharmaceutical compositions containing these compounds and processes for preparing them

Country Status (16)

Country Link
EP (1) EP0208200B1 (ja)
JP (1) JPH0739406B2 (ja)
AT (1) ATE52255T1 (ja)
AU (1) AU587263B2 (ja)
CA (1) CA1320723C (ja)
DE (2) DE3523466A1 (ja)
DK (1) DK168741B1 (ja)
ES (3) ES2000443A6 (ja)
FI (1) FI83417C (ja)
GR (1) GR861701B (ja)
HU (1) HU196193B (ja)
IE (1) IE59269B1 (ja)
NO (1) NO167736C (ja)
NZ (1) NZ216700A (ja)
PT (1) PT82879B (ja)
ZA (1) ZA864833B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347565A1 (de) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JPH0696391B2 (ja) * 1987-11-20 1994-11-30 マツダ株式会社 車両の後輪操舵装置
FR2763590B1 (fr) * 1997-05-22 2000-03-24 Synthelabo Derives d'acides[[[(arylmethyl)amino]carbonyl] alkyl]- aromatiques, leur preparation et leur application en therapeutique
EP2177221A1 (en) 2008-10-20 2010-04-21 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of substantially optically pure Repaglinide and precursors thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3100575A1 (de) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"
DE3225155A1 (de) * 1982-07-06 1984-01-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue n-benzylamide und deren salze, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3225188A1 (de) * 1982-07-06 1984-01-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue phenylessigsaeurederivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3347565A1 (de) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI862764A0 (fi) 1986-06-30
JPS625974A (ja) 1987-01-12
PT82879A (de) 1986-08-01
HU196193B (en) 1988-10-28
FI83417B (fi) 1991-03-28
GR861701B (en) 1986-10-31
NO862631L (no) 1987-01-02
ES2000443A6 (es) 1988-03-01
DK168741B1 (da) 1994-05-30
NO167736C (no) 1991-12-04
DK310986D0 (da) 1986-06-30
EP0208200A1 (de) 1987-01-14
EP0208200B1 (de) 1990-04-25
FI862764A (fi) 1987-01-02
IE59269B1 (en) 1994-01-26
JPH0739406B2 (ja) 1995-05-01
NZ216700A (en) 1989-06-28
ES2003758A6 (es) 1988-11-16
IE861752L (en) 1987-01-01
AU587263B2 (en) 1989-08-10
NO167736B (no) 1991-08-26
ES2003629A6 (es) 1988-11-01
AU5938386A (en) 1987-01-08
HUT43030A (en) 1987-09-28
DE3670636D1 (de) 1990-05-31
DK310986A (da) 1987-01-02
ATE52255T1 (de) 1990-05-15
CA1320723C (en) 1993-07-27
FI83417C (fi) 1991-07-10
DE3523466A1 (de) 1987-01-08
PT82879B (pt) 1989-01-17
NO862631D0 (no) 1986-06-30

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