ES8407475A1 - "un procedimiento para la preparacion de derivados de hidroxiimino y alcoxiimino de 1,4-dihidropiridina" - Google Patents

"un procedimiento para la preparacion de derivados de hidroxiimino y alcoxiimino de 1,4-dihidropiridina"

Info

Publication number
ES8407475A1
ES8407475A1 ES522884A ES522884A ES8407475A1 ES 8407475 A1 ES8407475 A1 ES 8407475A1 ES 522884 A ES522884 A ES 522884A ES 522884 A ES522884 A ES 522884A ES 8407475 A1 ES8407475 A1 ES 8407475A1
Authority
ES
Spain
Prior art keywords
unsubstituted
substituted
alkoxy
alkyl radical
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522884A
Other languages
English (en)
Other versions
ES522884A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierrel SpA
Original Assignee
Pierrel SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21679/82A external-priority patent/IT1198378B/it
Priority claimed from IT21044/83A external-priority patent/IT1164219B/it
Application filed by Pierrel SpA filed Critical Pierrel SpA
Publication of ES8407475A1 publication Critical patent/ES8407475A1/es
Publication of ES522884A0 publication Critical patent/ES522884A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE HIDROXIIMINO Y ALCOXIIMINO DE 1,4-DIHIDROPIRIDINA, DE SUS ENATIOMEROS, RACEMATOS, DIASTEREOISOMEROS E ISOMEROS (E) Y (Z) Y DE SUS SALES CON ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R-R SON VARIOS RADICALES; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTAGONISTA DEL CALCIO.CONSISTE EN LA REACCION DE UNA 5-ACIL-1-4-DIHIDROPIRIDINA CON UNA HIDROXILAMINA DE FORMULA H2N-O-R, EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DE LA SEPARACION DE LOS DIASTEREOISOMEROS (E) Y (Z).
ES522884A 1982-06-03 1983-06-01 "un procedimiento para la preparacion de derivados de hidroxiimino y alcoxiimino de 1,4-dihidropiridina" Granted ES522884A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21679/82A IT1198378B (it) 1982-06-03 1982-06-03 Composti idrossiminici e alcossiminici ad attivita' calcioanatagonista,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT21044/83A IT1164219B (it) 1983-05-11 1983-05-11 Composti idrossiminici e alcossiminici ad attivita' calcio-antagonista,procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (2)

Publication Number Publication Date
ES8407475A1 true ES8407475A1 (es) 1984-10-01
ES522884A0 ES522884A0 (es) 1984-10-01

Family

ID=26327747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522884A Granted ES522884A0 (es) 1982-06-03 1983-06-01 "un procedimiento para la preparacion de derivados de hidroxiimino y alcoxiimino de 1,4-dihidropiridina"

Country Status (6)

Country Link
US (1) US4508719A (es)
EP (1) EP0096299B1 (es)
AU (1) AU541712B2 (es)
CA (1) CA1221966A (es)
DE (1) DE3379107D1 (es)
ES (1) ES522884A0 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906646A (en) * 1983-03-31 1990-03-06 Board Of Governors Of Wayne State University Method and composition for the treatment of tumors by administering a platinum coordination compound and a calcium channel blocker compound of the dihydropyridine class
US4833150A (en) * 1985-03-14 1989-05-23 Nelson Research & Development Co. 1,4-dihydropyridines
US4849436A (en) * 1986-03-11 1989-07-18 Nelson Research & Development Co. 1,4-dihydropyridines
CN1276577C (zh) * 2001-04-25 2006-09-20 皇家菲利浦电子有限公司 具有两个压电层的结构和操作滤波器装置的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
DE2659665A1 (de) * 1976-12-30 1978-07-13 Nattermann A & Cie Neue 1,4-dihydropyridin-derivate
GB2050375B (en) * 1979-05-11 1983-02-23 Fujisawa Pharmaceutical Co 4-cyanophenyl-1,4-dihydropyridine compound processes for preparation thereof and pharmaceutical composition comprising the same
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
US4339584A (en) * 1980-12-22 1982-07-13 Sterling Drug Inc. Process for preparing 3-amino-5-(pyridinyl)-2(1H)-pyridinones via N-hydroxy-1,2-dihydro-2-oxo-5-(pyridinyl)-nicotinimidamide by reaction with polyphosphoric acid

Also Published As

Publication number Publication date
AU541712B2 (en) 1985-01-17
US4508719A (en) 1985-04-02
DE3379107D1 (en) 1989-03-09
EP0096299A2 (en) 1983-12-21
CA1221966A (en) 1987-05-19
ES522884A0 (es) 1984-10-01
EP0096299B1 (en) 1989-02-01
EP0096299A3 (en) 1984-05-23
AU1528383A (en) 1983-12-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303