ZA856524B - Substituted benzylphthalazinone derivatives - Google Patents

Substituted benzylphthalazinone derivatives

Info

Publication number
ZA856524B
ZA856524B ZA856524A ZA856524A ZA856524B ZA 856524 B ZA856524 B ZA 856524B ZA 856524 A ZA856524 A ZA 856524A ZA 856524 A ZA856524 A ZA 856524A ZA 856524 B ZA856524 B ZA 856524B
Authority
ZA
South Africa
Prior art keywords
substituted
group
benzylphthalazinone
derivatives
benzylphthalazinone derivatives
Prior art date
Application number
ZA856524A
Other languages
English (en)
Inventor
Juergen Engel
Gerhard Scheffler
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of ZA856524B publication Critical patent/ZA856524B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
ZA856524A 1984-09-14 1985-08-27 Substituted benzylphthalazinone derivatives ZA856524B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3433776 1984-09-14

Publications (1)

Publication Number Publication Date
ZA856524B true ZA856524B (en) 1986-04-30

Family

ID=6245402

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856524A ZA856524B (en) 1984-09-14 1985-08-27 Substituted benzylphthalazinone derivatives

Country Status (16)

Country Link
US (1) US4704387A (xx)
EP (1) EP0174464B1 (xx)
JP (1) JPH0699425B2 (xx)
AT (1) ATE49205T1 (xx)
CA (1) CA1263652A (xx)
DD (1) DD240205A5 (xx)
DE (1) DE3575135D1 (xx)
DK (1) DK167118B1 (xx)
ES (2) ES8605510A1 (xx)
GR (1) GR852219B (xx)
HU (1) HU197740B (xx)
IE (1) IE64839B1 (xx)
IL (1) IL75989A0 (xx)
MX (1) MX159034A (xx)
PT (1) PT81122B (xx)
ZA (1) ZA856524B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3677322D1 (de) * 1985-11-11 1991-03-07 Asta Pharma Ag 4-benzyl-1-(2h)-phthalazinon-derivate.
EP0289939A1 (de) * 1987-05-08 1988-11-09 ASTA Pharma AG Neue 4-Benzyl-1-(2H)-phthalazinon-Derivate mit einem Aminosäurerest
ES2053678T3 (es) * 1987-11-13 1994-08-01 Asta Medica Ag Procedimiento para preparar un medicamento con contenido de azelastina para la aplicacion nasal y/u ocular.
US5232919A (en) * 1987-11-13 1993-08-03 Asta Pharma Aktiengesellschaft Azelastine embonate and compositions which contain it
US5271946A (en) * 1988-04-20 1993-12-21 Asta Pharma Aktiengesellschaft Controlled release azelastine-containing pharmaceutical compositions
MC2025A1 (fr) * 1988-04-20 1990-04-25 Asta Pharma Ag Medicament contenant de l'azelastine et capable de liberer celle-ci de facon controlee
ATE107643T1 (de) * 1989-05-05 1994-07-15 Asta Medica Ag Salze des azelastins mit verbesserter löslichkeit.
JPH04198180A (ja) * 1990-11-28 1992-07-17 Eezai Kagaku Kk ベンジルフタラゾン誘導体の製造方法
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
PL2522365T3 (pl) 2004-11-24 2017-05-31 Meda Pharmaceuticals Inc. Kompozycje zawierające azelastynę i sposoby ich zastosowania
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
EA200801996A1 (ru) * 2006-04-20 2009-04-28 Глаксо Груп Лимитед 2-замещенные производные 4-бензилфталазинонов в качестве гистаминовых h1- и h3-антагонистов
ES2369320T3 (es) * 2007-10-11 2011-11-29 Glaxo Group Limited Compuestos de ftalazina y pirido(3,4-d)piridazina como antagonistas del receptor h1.
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
CH572914A5 (xx) * 1971-01-22 1976-02-27 Asta Werke Ag Chem Fab
DE2114884A1 (de) * 1971-03-27 1972-10-12 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Basisch substituierte Derivate des 1(2H)-Phthalazinons
US3813384A (en) * 1972-01-17 1974-05-28 Asta Werke Ag Chem Fab Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones

Also Published As

Publication number Publication date
CA1263652A (en) 1989-12-05
IL75989A0 (en) 1985-12-31
ATE49205T1 (de) 1990-01-15
DK167118B1 (da) 1993-08-30
JPS6172782A (ja) 1986-04-14
EP0174464B1 (de) 1990-01-03
PT81122B (pt) 1988-01-22
HUT38340A (en) 1986-05-28
JPH0699425B2 (ja) 1994-12-07
ES546959A0 (es) 1986-03-16
EP0174464A2 (de) 1986-03-19
IE64839B1 (en) 1995-09-06
DK416585A (da) 1986-03-15
DD240205A5 (de) 1986-10-22
GR852219B (xx) 1986-01-14
ES546971A0 (es) 1986-03-16
ES8605510A1 (es) 1986-03-16
DE3575135D1 (de) 1990-02-08
MX159034A (es) 1989-04-13
EP0174464A3 (en) 1986-12-30
ES8605509A1 (es) 1986-03-16
PT81122A (de) 1985-10-01
DK416585D0 (da) 1985-09-13
US4704387A (en) 1987-11-03
HU197740B (en) 1989-05-29
IE852270L (en) 1986-03-14

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