DK416585A - Substituerede benzylphthalazinonderivater - Google Patents

Substituerede benzylphthalazinonderivater Download PDF

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Publication number
DK416585A
DK416585A DK416585A DK416585A DK416585A DK 416585 A DK416585 A DK 416585A DK 416585 A DK416585 A DK 416585A DK 416585 A DK416585 A DK 416585A DK 416585 A DK416585 A DK 416585A
Authority
DK
Denmark
Prior art keywords
benzylphthalazinine
derivatives
substituted
group
compounds
Prior art date
Application number
DK416585A
Other languages
English (en)
Other versions
DK167118B1 (da
DK416585D0 (da
Inventor
Juergen Engel
Gerhard Scheffler
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of DK416585D0 publication Critical patent/DK416585D0/da
Publication of DK416585A publication Critical patent/DK416585A/da
Application granted granted Critical
Publication of DK167118B1 publication Critical patent/DK167118B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK416585A 1984-09-14 1985-09-13 Substituerede benzylphthalazinonderivater, fremgangsmaade til fremstilling deraf, laegemidler indeholdende derivaterne, samt anvendelse af derivaterne til fremstilling af laegemidler DK167118B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3433776 1984-09-14
DE3433776 1984-09-14

Publications (3)

Publication Number Publication Date
DK416585D0 DK416585D0 (da) 1985-09-13
DK416585A true DK416585A (da) 1986-03-15
DK167118B1 DK167118B1 (da) 1993-08-30

Family

ID=6245402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK416585A DK167118B1 (da) 1984-09-14 1985-09-13 Substituerede benzylphthalazinonderivater, fremgangsmaade til fremstilling deraf, laegemidler indeholdende derivaterne, samt anvendelse af derivaterne til fremstilling af laegemidler

Country Status (16)

Country Link
US (1) US4704387A (da)
EP (1) EP0174464B1 (da)
JP (1) JPH0699425B2 (da)
AT (1) ATE49205T1 (da)
CA (1) CA1263652A (da)
DD (1) DD240205A5 (da)
DE (1) DE3575135D1 (da)
DK (1) DK167118B1 (da)
ES (2) ES8605509A1 (da)
GR (1) GR852219B (da)
HU (1) HU197740B (da)
IE (1) IE64839B1 (da)
IL (1) IL75989A0 (da)
MX (1) MX159034A (da)
PT (1) PT81122B (da)
ZA (1) ZA856524B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222191B1 (de) * 1985-11-11 1991-01-30 ASTA Pharma AG 4-Benzyl-1-(2H)-phthalazinon-Derivate
EP0289939A1 (de) * 1987-05-08 1988-11-09 ASTA Pharma AG Neue 4-Benzyl-1-(2H)-phthalazinon-Derivate mit einem Aminosäurerest
US5232919A (en) * 1987-11-13 1993-08-03 Asta Pharma Aktiengesellschaft Azelastine embonate and compositions which contain it
ES2053678T3 (es) * 1987-11-13 1994-08-01 Asta Medica Ag Procedimiento para preparar un medicamento con contenido de azelastina para la aplicacion nasal y/u ocular.
US5271946A (en) * 1988-04-20 1993-12-21 Asta Pharma Aktiengesellschaft Controlled release azelastine-containing pharmaceutical compositions
MC2025A1 (fr) * 1988-04-20 1990-04-25 Asta Pharma Ag Medicament contenant de l'azelastine et capable de liberer celle-ci de facon controlee
DE4013696A1 (de) * 1989-05-05 1990-11-08 Asta Pharma Ag Salze des azelastins mit verbesserter loeslichkeit
JPH04198180A (ja) * 1990-11-28 1992-07-17 Eezai Kagaku Kk ベンジルフタラゾン誘導体の製造方法
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
EP2007735B1 (en) * 2006-04-20 2010-10-27 Glaxo Group Limited 2-substituted 4-benzylphthalazinone derivatives as histamine h1 and h3 antagonists
ES2369320T3 (es) * 2007-10-11 2011-11-29 Glaxo Group Limited Compuestos de ftalazina y pirido(3,4-d)piridazina como antagonistas del receptor h1.
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
CH572914A5 (da) * 1971-01-22 1976-02-27 Asta Werke Ag Chem Fab
DE2114884A1 (de) * 1971-03-27 1972-10-12 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Basisch substituierte Derivate des 1(2H)-Phthalazinons
US3813384A (en) * 1972-01-17 1974-05-28 Asta Werke Ag Chem Fab Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones

Also Published As

Publication number Publication date
CA1263652A (en) 1989-12-05
ZA856524B (en) 1986-04-30
MX159034A (es) 1989-04-13
ES546959A0 (es) 1986-03-16
PT81122B (pt) 1988-01-22
HU197740B (en) 1989-05-29
DK167118B1 (da) 1993-08-30
DD240205A5 (de) 1986-10-22
DE3575135D1 (de) 1990-02-08
IE64839B1 (en) 1995-09-06
ES8605509A1 (es) 1986-03-16
EP0174464A2 (de) 1986-03-19
GR852219B (da) 1986-01-14
ATE49205T1 (de) 1990-01-15
IE852270L (en) 1986-03-14
JPS6172782A (ja) 1986-04-14
PT81122A (de) 1985-10-01
EP0174464B1 (de) 1990-01-03
ES8605510A1 (es) 1986-03-16
DK416585D0 (da) 1985-09-13
ES546971A0 (es) 1986-03-16
HUT38340A (en) 1986-05-28
US4704387A (en) 1987-11-03
JPH0699425B2 (ja) 1994-12-07
IL75989A0 (en) 1985-12-31
EP0174464A3 (en) 1986-12-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed