ZA855769B - Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations - Google Patents

Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations

Info

Publication number
ZA855769B
ZA855769B ZA855769A ZA855769A ZA855769B ZA 855769 B ZA855769 B ZA 855769B ZA 855769 A ZA855769 A ZA 855769A ZA 855769 A ZA855769 A ZA 855769A ZA 855769 B ZA855769 B ZA 855769B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
controlled
regulatory peptides
injection formulations
Prior art date
Application number
ZA855769A
Other languages
English (en)
Inventor
Juergen Kurt Sandow
Heinz-Ruediger Seidel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA855769B publication Critical patent/ZA855769B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
ZA855769A 1984-08-01 1985-07-31 Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations ZA855769B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843428372 DE3428372A1 (de) 1984-08-01 1984-08-01 Mikrokapseln von regulatorischen peptiden mit kontrollierter freisetzung, verfahren zu ihrer herstellung und injektionszubereitungen

Publications (1)

Publication Number Publication Date
ZA855769B true ZA855769B (en) 1986-03-26

Family

ID=6242124

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855769A ZA855769B (en) 1984-08-01 1985-07-31 Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations

Country Status (12)

Country Link
EP (1) EP0172422A3 (es)
JP (1) JPS6143119A (es)
KR (1) KR860001592A (es)
AU (1) AU4567785A (es)
DE (1) DE3428372A1 (es)
DK (1) DK348185A (es)
ES (1) ES8608313A1 (es)
GR (1) GR851872B (es)
HU (1) HU195108B (es)
IL (1) IL75936A0 (es)
PT (1) PT80890B (es)
ZA (1) ZA855769B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3712095A1 (de) * 1987-04-10 1988-10-20 Lentia Gmbh Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe
NZ224549A (en) * 1987-05-29 1990-04-26 Ici Australia Operations Controlled release polymer microspheres containing at least one active agent
JP2837675B2 (ja) * 1987-09-22 1998-12-16 中外製薬株式会社 徐放性微粒製剤
DE3738228A1 (de) * 1987-11-11 1989-05-24 Hoechst Ag Verfahren zur herstellung von bioabbaubaren mikrokapseln wasserloeslicher peptide und proteine sowie nach diesem verfahren erhaltene mikrokapseln
DE59006217D1 (de) * 1989-11-30 1994-07-28 Danubia Petrochem Polymere Nicht wirkstoffretardierender Pressling, Verfahren zu dessen Herstellung und Verwendung von Polyhydroxybuttersäure zur Herstellung eines solchen Presslings.
JP2997488B2 (ja) * 1989-12-25 2000-01-11 興研株式会社 腫瘍細胞増殖抑制剤
DE4000155A1 (de) * 1990-01-04 1991-07-11 Chemie Linz Deutschland Nicht wirkstoffretardierender pressling, verfahren zu dessen herstellung und verwendung von polyhydroxybuttersaeure zur herstellung eines solchen presslings
CA2046830C (en) * 1990-07-19 1999-12-14 Patrick P. Deluca Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
DE4041563A1 (de) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren
JPH0580599U (ja) * 1992-04-03 1993-11-02 株式会社丸島アクアシステム 閉鎖系水域における水質浄化装置
DE4223169C1 (de) 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Verfahren zur Mikroverkapselung wasserlöslicher Wirkstoffe
DE4427201C2 (de) * 1993-11-26 1996-09-12 Ges Innenhochdruckverfahren Verfahren zur Herstellung von hohlen Nockenwellen
US7615233B2 (en) 2001-07-10 2009-11-10 Canon Kabushiki Kaisha Particulate construct comprising polyhydroxyalkanoate and method for producing it
JP2004331750A (ja) 2003-05-02 2004-11-25 Canon Inc ポリヒドロキシアルカノエートを含有する磁性構造体及びその製造方法ならびにその用途
GB2470378A (en) * 2009-05-20 2010-11-24 Univ Westminster A controlled release composition for intraocular delivery of a therapeutic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644768A5 (de) * 1977-08-25 1984-08-31 Sandoz Ag Verfahren zur herstellung von mikrokugeln.
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
GB2108074A (en) * 1981-10-28 1983-05-11 Pa Management Consult Preservation and projection of active substances

Also Published As

Publication number Publication date
GR851872B (es) 1985-12-02
HU195108B (en) 1988-04-28
AU4567785A (en) 1986-02-06
JPS6143119A (ja) 1986-03-01
IL75936A0 (en) 1985-12-31
KR860001592A (ko) 1986-03-20
HUT41982A (en) 1987-06-29
EP0172422A3 (de) 1986-05-07
PT80890B (de) 1987-03-24
PT80890A (de) 1985-08-01
ES8608313A1 (es) 1986-07-01
EP0172422A2 (de) 1986-02-26
DE3428372A1 (de) 1986-02-13
DK348185A (da) 1986-02-02
ES545723A0 (es) 1986-07-01
DK348185D0 (da) 1985-07-31

Similar Documents

Publication Publication Date Title
IL74848A0 (en) Implantable formulations of regulatory peptides with controlled release,and process for their preparation
GB2211413B (en) Pharmaceutical formulations comprising microcapsules
EP0194838A3 (en) Controlled-release pharmaceutical formulation
EP0224146A3 (en) Pharmaceutical preparation for the controlled release of active ingredients
ZA855769B (en) Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations
GB8421706D0 (en) Pharmaceutical preparations
PT83594A (en) Process for preparation of insecticidal n:-substituted-n,n:-diacyllhydrazines and of insecticidal compositions containing the same
ZA853462B (en) Controlled release pharmaceutical preparations
EP0215596A3 (en) Composition for injection of active type vitamins d3
ZA862141B (en) Substituted 1,8-naphthyridinones,processes for their preparation and pharmaceutical compositions containing them
ZA86936B (en) 11beta-phenyl-gonanes,their manufacture and pharmaceutical preparations containing them
IL88998A0 (en) Novel amino acid glycerides,processes for their preparation,and pharmaceutical compositions containing them
GR3002266T3 (en) Process for the preparation of single dosage administration forms, and administration forms thus obtained
IL81990A0 (en) Compounds and pharmaceutical preparations having calcium regulatory activity
GR860301B (en) -cis-1,3,5-triamino-2,4,6-cyclohexantriol derivatives preparation process therefor and pharmaceutical preparations comprising them
GB8520189D0 (en) Pharmaceutical preparations
ZA852279B (en) Pharmaceutical preparations
PT83231A (en) Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same
HK73992A (en) Rodent-repellent microcapsules and preparations thereof
EP0175323A3 (en) Biologically active peptides, processes for preparing them and pharmaceutical compositions
ZA854519B (en) 5,6-dihydro-4h-cyclopenta(b)thiophene-6-carboxylic acids preparation processes and medicines containing them
DE3665720D1 (en) Novel ll-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions
GB8606293D0 (en) Antigenically active protein
DE3572671D1 (en) New hypocalcemic polypeptides, preparation thereof and drugs containing these active principles
GB8414612D0 (en) Preparation of protected protein