AU4567785A - Polyhdroxybutyric acid as excipient in controlled release formulatons of peptides - Google Patents

Polyhdroxybutyric acid as excipient in controlled release formulatons of peptides

Info

Publication number
AU4567785A
AU4567785A AU45677/85A AU4567785A AU4567785A AU 4567785 A AU4567785 A AU 4567785A AU 45677/85 A AU45677/85 A AU 45677/85A AU 4567785 A AU4567785 A AU 4567785A AU 4567785 A AU4567785 A AU 4567785A
Authority
AU
Australia
Prior art keywords
polyhdroxybutyric
formulatons
excipient
peptides
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45677/85A
Inventor
Jurgen Kurt Dandow
Heinz-Rudiger Seidel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4567785A publication Critical patent/AU4567785A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AU45677/85A 1984-08-01 1985-07-31 Polyhdroxybutyric acid as excipient in controlled release formulatons of peptides Abandoned AU4567785A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843428372 DE3428372A1 (en) 1984-08-01 1984-08-01 CONTROLLED RELEASE REGULAR PEPTIDES MICROCAPSULES, PRODUCTION METHOD AND INJECTION PREPARATIONS
DE3428372 1984-08-01

Publications (1)

Publication Number Publication Date
AU4567785A true AU4567785A (en) 1986-02-06

Family

ID=6242124

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45677/85A Abandoned AU4567785A (en) 1984-08-01 1985-07-31 Polyhdroxybutyric acid as excipient in controlled release formulatons of peptides

Country Status (12)

Country Link
EP (1) EP0172422A3 (en)
JP (1) JPS6143119A (en)
KR (1) KR860001592A (en)
AU (1) AU4567785A (en)
DE (1) DE3428372A1 (en)
DK (1) DK348185A (en)
ES (1) ES8608313A1 (en)
GR (1) GR851872B (en)
HU (1) HU195108B (en)
IL (1) IL75936A0 (en)
PT (1) PT80890B (en)
ZA (1) ZA855769B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009121A1 (en) * 1987-05-29 1988-12-01 Ici Australia Operations Proprietary Limited Controlled release polymer microspheres
AU656897B2 (en) * 1990-07-19 1995-02-23 University Of Kentucky Research Foundation, The Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3712095A1 (en) * 1987-04-10 1988-10-20 Lentia Gmbh BINDER-FREE GRANULES WITH DELAYED DELIVERY OF ACTIVE SUBSTANCES
JP2837675B2 (en) * 1987-09-22 1998-12-16 中外製薬株式会社 Sustained-release fine-particle preparation
DE3738228A1 (en) * 1987-11-11 1989-05-24 Hoechst Ag METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS
DE59006217D1 (en) * 1989-11-30 1994-07-28 Danubia Petrochem Polymere Non-drug retardant compact, process for its production and use of polyhydroxybutyric acid for the production of such a compact.
JP2997488B2 (en) * 1989-12-25 2000-01-11 興研株式会社 Tumor cell growth inhibitor
DE4000155A1 (en) * 1990-01-04 1991-07-11 Chemie Linz Deutschland Pressed tablet for oral admin. with non-retarded release of agent - comprises homo and/or copolymer of D-(-)-3-hydroxybutyric acid, disintegrating and active-agents and has good storage stability
DE4041563A1 (en) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS
JPH0580599U (en) * 1992-04-03 1993-11-02 株式会社丸島アクアシステム Water purification device in closed water area
DE4223169C1 (en) 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Process for the microencapsulation of water-soluble active substances
DE4427201C2 (en) * 1993-11-26 1996-09-12 Ges Innenhochdruckverfahren Process for the production of hollow camshafts
CN1278675C (en) 2001-07-10 2006-10-11 佳能株式会社 Granular body contg. polydroxy alkoxide acid ester
JP2004331750A (en) 2003-05-02 2004-11-25 Canon Inc Magnetic structure comprising polyhydroxyalkanoate and method for producing the same and use thereof
GB2470378A (en) * 2009-05-20 2010-11-24 Univ Westminster A controlled release composition for intraocular delivery of a therapeutic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644768A5 (en) * 1977-08-25 1984-08-31 Sandoz Ag METHOD FOR PRODUCING MICROBALLS.
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
GB2108074A (en) * 1981-10-28 1983-05-11 Pa Management Consult Preservation and projection of active substances

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009121A1 (en) * 1987-05-29 1988-12-01 Ici Australia Operations Proprietary Limited Controlled release polymer microspheres
AU656897B2 (en) * 1990-07-19 1995-02-23 University Of Kentucky Research Foundation, The Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer

Also Published As

Publication number Publication date
IL75936A0 (en) 1985-12-31
EP0172422A2 (en) 1986-02-26
JPS6143119A (en) 1986-03-01
ZA855769B (en) 1986-03-26
HU195108B (en) 1988-04-28
GR851872B (en) 1985-12-02
KR860001592A (en) 1986-03-20
PT80890B (en) 1987-03-24
DE3428372A1 (en) 1986-02-13
DK348185A (en) 1986-02-02
PT80890A (en) 1985-08-01
HUT41982A (en) 1987-06-29
ES545723A0 (en) 1986-07-01
ES8608313A1 (en) 1986-07-01
DK348185D0 (en) 1985-07-31
EP0172422A3 (en) 1986-05-07

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