ZA855769B - Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations - Google Patents

Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations

Info

Publication number
ZA855769B
ZA855769B ZA855769A ZA855769A ZA855769B ZA 855769 B ZA855769 B ZA 855769B ZA 855769 A ZA855769 A ZA 855769A ZA 855769 A ZA855769 A ZA 855769A ZA 855769 B ZA855769 B ZA 855769B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
controlled
regulatory peptides
injection formulations
Prior art date
Application number
ZA855769A
Inventor
Juergen Kurt Sandow
Heinz-Ruediger Seidel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA855769B publication Critical patent/ZA855769B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
ZA855769A 1984-08-01 1985-07-31 Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations ZA855769B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843428372 DE3428372A1 (en) 1984-08-01 1984-08-01 CONTROLLED RELEASE REGULAR PEPTIDES MICROCAPSULES, PRODUCTION METHOD AND INJECTION PREPARATIONS

Publications (1)

Publication Number Publication Date
ZA855769B true ZA855769B (en) 1986-03-26

Family

ID=6242124

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855769A ZA855769B (en) 1984-08-01 1985-07-31 Controlled-release microcapsules of regulatory peptides,processes for their preparation and injection formulations

Country Status (12)

Country Link
EP (1) EP0172422A3 (en)
JP (1) JPS6143119A (en)
KR (1) KR860001592A (en)
AU (1) AU4567785A (en)
DE (1) DE3428372A1 (en)
DK (1) DK348185A (en)
ES (1) ES8608313A1 (en)
GR (1) GR851872B (en)
HU (1) HU195108B (en)
IL (1) IL75936A0 (en)
PT (1) PT80890B (en)
ZA (1) ZA855769B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3712095A1 (en) * 1987-04-10 1988-10-20 Lentia Gmbh BINDER-FREE GRANULES WITH DELAYED DELIVERY OF ACTIVE SUBSTANCES
NZ224549A (en) * 1987-05-29 1990-04-26 Ici Australia Operations Controlled release polymer microspheres containing at least one active agent
JP2837675B2 (en) * 1987-09-22 1998-12-16 中外製薬株式会社 Sustained-release fine-particle preparation
DE3738228A1 (en) * 1987-11-11 1989-05-24 Hoechst Ag METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS
DE59006217D1 (en) * 1989-11-30 1994-07-28 Danubia Petrochem Polymere Non-drug retardant compact, process for its production and use of polyhydroxybutyric acid for the production of such a compact.
JP2997488B2 (en) * 1989-12-25 2000-01-11 興研株式会社 Tumor cell growth inhibitor
DE4000155A1 (en) * 1990-01-04 1991-07-11 Chemie Linz Deutschland Pressed tablet for oral admin. with non-retarded release of agent - comprises homo and/or copolymer of D-(-)-3-hydroxybutyric acid, disintegrating and active-agents and has good storage stability
CA2046830C (en) * 1990-07-19 1999-12-14 Patrick P. Deluca Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
DE4041563A1 (en) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh METHOD FOR PRODUCING ACTIVE MICROPARTICLES FROM HYDROLYTICALLY DEGRADABLE POLYMERS
JPH0580599U (en) * 1992-04-03 1993-11-02 株式会社丸島アクアシステム Water purification device in closed water area
DE4223169C1 (en) 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Process for the microencapsulation of water-soluble active substances
DE4427201C2 (en) * 1993-11-26 1996-09-12 Ges Innenhochdruckverfahren Process for the production of hollow camshafts
US7615233B2 (en) 2001-07-10 2009-11-10 Canon Kabushiki Kaisha Particulate construct comprising polyhydroxyalkanoate and method for producing it
JP2004331750A (en) 2003-05-02 2004-11-25 Canon Inc Magnetic structure comprising polyhydroxyalkanoate and method for producing the same and use thereof
GB2470378A (en) * 2009-05-20 2010-11-24 Univ Westminster A controlled release composition for intraocular delivery of a therapeutic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649217A5 (en) * 1977-08-25 1985-05-15 Sandoz Ag BROMOCRIPTIN CONTAINING MICROCAPSULES.
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
GB2108074A (en) * 1981-10-28 1983-05-11 Pa Management Consult Preservation and projection of active substances

Also Published As

Publication number Publication date
HU195108B (en) 1988-04-28
ES545723A0 (en) 1986-07-01
GR851872B (en) 1985-12-02
DK348185A (en) 1986-02-02
HUT41982A (en) 1987-06-29
AU4567785A (en) 1986-02-06
JPS6143119A (en) 1986-03-01
DE3428372A1 (en) 1986-02-13
IL75936A0 (en) 1985-12-31
PT80890A (en) 1985-08-01
EP0172422A3 (en) 1986-05-07
ES8608313A1 (en) 1986-07-01
KR860001592A (en) 1986-03-20
PT80890B (en) 1987-03-24
DK348185D0 (en) 1985-07-31
EP0172422A2 (en) 1986-02-26

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