ZA852035B - Genetic expression of somatostatin as hybrid polypeptide - Google Patents

Genetic expression of somatostatin as hybrid polypeptide

Info

Publication number
ZA852035B
ZA852035B ZA852035A ZA852035A ZA852035B ZA 852035 B ZA852035 B ZA 852035B ZA 852035 A ZA852035 A ZA 852035A ZA 852035 A ZA852035 A ZA 852035A ZA 852035 B ZA852035 B ZA 852035B
Authority
ZA
South Africa
Prior art keywords
somatostatin
genetic expression
hybrid polypeptide
polypeptide
hybrid
Prior art date
Application number
ZA852035A
Other languages
English (en)
Inventor
Umberto Canosi
Gabriele De Fazio
Stefano Villa
Silvia Donini
Original Assignee
Serono Ist Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Ist Farm filed Critical Serono Ist Farm
Publication of ZA852035B publication Critical patent/ZA852035B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA852035A 1984-03-30 1985-03-19 Genetic expression of somatostatin as hybrid polypeptide ZA852035B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47976/84A IT1198443B (it) 1984-03-30 1984-03-30 Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina

Publications (1)

Publication Number Publication Date
ZA852035B true ZA852035B (en) 1985-11-27

Family

ID=11263727

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA852035A ZA852035B (en) 1984-03-30 1985-03-19 Genetic expression of somatostatin as hybrid polypeptide

Country Status (11)

Country Link
EP (1) EP0160190A3 (fr)
JP (1) JPS615788A (fr)
AU (2) AU4046185A (fr)
CA (1) CA1301676C (fr)
DK (1) DK131285A (fr)
ES (1) ES8605284A1 (fr)
FI (1) FI851288L (fr)
IL (1) IL74620A (fr)
IT (1) IT1198443B (fr)
NO (1) NO851308L (fr)
ZA (1) ZA852035B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1234977B (it) 1985-03-22 1992-06-09 Serono Ist Farm Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita
JPS63304996A (ja) * 1987-06-04 1988-12-13 Toray Ind Inc 融合タンパク質およびその製造方法
JPH0722517B2 (ja) * 1989-08-24 1995-03-15 株式会社三和化学研究所 モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU257278A (en) * 1977-11-08 1984-02-29 Genentech Inc Process for obtaining a recombinat clone carrier
GB2052516B (en) * 1979-06-01 1983-06-29 Searle & Co Plasmid vectors production and use thereof
IE52122B1 (en) * 1980-08-25 1987-06-24 Univ California Somatostatin or somatostatin precursors
GB2102006B (en) * 1981-06-16 1984-11-28 Takeda Chemical Industries Ltd Deoxyribonucleic acids, their production and use
JPS59203495A (ja) * 1983-04-28 1984-11-17 Kyowa Hakko Kogyo Co Ltd 外来遺伝子の新規な発現方法

Also Published As

Publication number Publication date
FI851288L (fi) 1985-10-01
CA1301676C (fr) 1992-05-26
DK131285D0 (da) 1985-03-22
ES541782A0 (es) 1986-04-01
FI851288A0 (fi) 1985-03-29
IT8447976A0 (it) 1984-03-30
IL74620A0 (en) 1985-06-30
EP0160190A3 (fr) 1987-07-15
AU611048B2 (en) 1991-05-30
ES8605284A1 (es) 1986-04-01
DK131285A (da) 1985-10-01
JPS615788A (ja) 1986-01-11
AU3954789A (en) 1989-11-30
EP0160190A2 (fr) 1985-11-06
AU4046185A (en) 1985-10-31
IL74620A (en) 1990-12-23
IT1198443B (it) 1988-12-21
NO851308L (no) 1985-10-01

Similar Documents

Publication Publication Date Title
GB8715059D0 (en) Genetic modification of yeast
PL256012A1 (en) Method of obtaining peptides
EP0303692A4 (en) Cloning of lfa-1
ZA858328B (en) Peptides selected from amino acid residues 11 to 23 of vip
AU8481082A (en) Recombinant dna production of rennins
GB8608897D0 (en) Polypeptide
IL74661A0 (en) Preparation of proteins
EP0173384A3 (en) Polypeptide relating to alpha-hanp
AU4033985A (en) Compositions of calcitonin-gene related peptide
EP0176299A3 (en) Mutual separation of proteins
HUT38676A (en) Vector bearing recombinant dna cosmide
ZA857090B (en) Mutual separation of proteins
GB8704890D0 (en) Protection of proteins
IL81072A0 (en) Immunoamplifier polypeptide compositions
IL74620A0 (en) Genetic expression of somatostatin as hybrid polypeptide
GB8519474D0 (en) Anti-asthmatic composition
EP0166391A3 (en) Sequence controller
DE3568298D1 (en) Process for hydrolysis of peptide or protein
GB2159830B (en) Exraction of oilseeds
GB8529759D0 (en) Polypeptide
GB2161293B (en) Sequence controller
GB8414612D0 (en) Preparation of protected protein
GB8424340D0 (en) Cloning of dna
GB8526818D0 (en) Operation of bioreactor
IE840059L (en) Recombinant dna expression vectors