FI851288A0 - Genetisk expression av somatostatin som hybridpolypeptid. - Google Patents

Genetisk expression av somatostatin som hybridpolypeptid.

Info

Publication number
FI851288A0
FI851288A0 FI851288A FI851288A FI851288A0 FI 851288 A0 FI851288 A0 FI 851288A0 FI 851288 A FI851288 A FI 851288A FI 851288 A FI851288 A FI 851288A FI 851288 A0 FI851288 A0 FI 851288A0
Authority
FI
Finland
Prior art keywords
hybridpolypeptid
genetisk
som
somatostatin
expression
Prior art date
Application number
FI851288A
Other languages
English (en)
Other versions
FI851288L (fi
Inventor
Umberto Canosi
Fazio Gabriele De
Stefano Villa
Silvia Domini
Original Assignee
Serono Ist Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Ist Farm filed Critical Serono Ist Farm
Publication of FI851288A0 publication Critical patent/FI851288A0/fi
Publication of FI851288L publication Critical patent/FI851288L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI851288A 1984-03-30 1985-03-29 Genetisk expression av somatostatin som hybridpolypeptid. FI851288L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47976/84A IT1198443B (it) 1984-03-30 1984-03-30 Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina

Publications (2)

Publication Number Publication Date
FI851288A0 true FI851288A0 (fi) 1985-03-29
FI851288L FI851288L (fi) 1985-10-01

Family

ID=11263727

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851288A FI851288L (fi) 1984-03-30 1985-03-29 Genetisk expression av somatostatin som hybridpolypeptid.

Country Status (11)

Country Link
EP (1) EP0160190A3 (fi)
JP (1) JPS615788A (fi)
AU (2) AU4046185A (fi)
CA (1) CA1301676C (fi)
DK (1) DK131285A (fi)
ES (1) ES8605284A1 (fi)
FI (1) FI851288L (fi)
IL (1) IL74620A (fi)
IT (1) IT1198443B (fi)
NO (1) NO851308L (fi)
ZA (1) ZA852035B (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1234977B (it) 1985-03-22 1992-06-09 Serono Ist Farm Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita
JPS63304996A (ja) * 1987-06-04 1988-12-13 Toray Ind Inc 融合タンパク質およびその製造方法
JPH0722517B2 (ja) * 1989-08-24 1995-03-15 株式会社三和化学研究所 モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU257278A (en) * 1977-11-08 1984-02-29 Genentech Inc Process for obtaining a recombinat clone carrier
GB2052516B (en) * 1979-06-01 1983-06-29 Searle & Co Plasmid vectors production and use thereof
IE52122B1 (en) * 1980-08-25 1987-06-24 Univ California Somatostatin or somatostatin precursors
GB2102006B (en) * 1981-06-16 1984-11-28 Takeda Chemical Industries Ltd Deoxyribonucleic acids, their production and use
JPS59203495A (ja) * 1983-04-28 1984-11-17 Kyowa Hakko Kogyo Co Ltd 外来遺伝子の新規な発現方法

Also Published As

Publication number Publication date
FI851288L (fi) 1985-10-01
CA1301676C (en) 1992-05-26
DK131285D0 (da) 1985-03-22
ES541782A0 (es) 1986-04-01
IT8447976A0 (it) 1984-03-30
IL74620A0 (en) 1985-06-30
EP0160190A3 (en) 1987-07-15
AU611048B2 (en) 1991-05-30
ES8605284A1 (es) 1986-04-01
DK131285A (da) 1985-10-01
JPS615788A (ja) 1986-01-11
AU3954789A (en) 1989-11-30
EP0160190A2 (en) 1985-11-06
AU4046185A (en) 1985-10-31
IL74620A (en) 1990-12-23
IT1198443B (it) 1988-12-21
ZA852035B (en) 1985-11-27
NO851308L (no) 1985-10-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: ISTITUTO FARMACOLOGICO SERONO SPA