ZA851317B - Ester prodrugs of oxicams - Google Patents

Ester prodrugs of oxicams

Info

Publication number
ZA851317B
ZA851317B ZA851317A ZA851317A ZA851317B ZA 851317 B ZA851317 B ZA 851317B ZA 851317 A ZA851317 A ZA 851317A ZA 851317 A ZA851317 A ZA 851317A ZA 851317 B ZA851317 B ZA 851317B
Authority
ZA
South Africa
Prior art keywords
oxicams
ester prodrugs
prodrugs
ester
Prior art date
Application number
ZA851317A
Other languages
English (en)
Inventor
Joseph George Lombardino
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA851317B publication Critical patent/ZA851317B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
ZA851317A 1984-02-23 1985-02-21 Ester prodrugs of oxicams ZA851317B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58268484A 1984-02-23 1984-02-23

Publications (1)

Publication Number Publication Date
ZA851317B true ZA851317B (en) 1986-10-29

Family

ID=24330094

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA851317A ZA851317B (en) 1984-02-23 1985-02-21 Ester prodrugs of oxicams

Country Status (22)

Country Link
JP (1) JPS60184077A (ja)
KR (1) KR850006198A (ja)
AU (1) AU552478B2 (ja)
BE (1) BE901783A (ja)
DD (1) DD232045A5 (ja)
DE (1) DE3505576A1 (ja)
DK (1) DK81185A (ja)
ES (1) ES8606312A1 (ja)
FI (1) FI850742L (ja)
FR (1) FR2565980A1 (ja)
GB (1) GB2154585A (ja)
GR (1) GR850442B (ja)
HU (1) HUT37616A (ja)
IL (1) IL74407A0 (ja)
IT (1) IT1185514B (ja)
LU (1) LU85780A1 (ja)
NL (1) NL8500485A (ja)
NO (1) NO850725L (ja)
PL (1) PL252023A1 (ja)
PT (1) PT79988B (ja)
SE (1) SE8500889L (ja)
ZA (1) ZA851317B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623486A (en) * 1985-05-29 1986-11-18 Pfizer Inc. [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
US4610982A (en) * 1985-06-03 1986-09-09 Pfizer Inc. Anti-inflammatory benzo- and thieno-1,2-thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
JP5378221B2 (ja) * 2006-10-11 2013-12-25 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するオキシカム及び関連化合物の正荷電水溶性プロドラッグ
CN101687792B (zh) 2007-06-04 2016-03-02 于崇曦 具有快速皮肤和生物膜穿透速度的非甾体抗炎药的前药及其医药用途
KR101946297B1 (ko) 2008-12-04 2019-02-11 충시 위 고투과력을 가진 조성물 및 이의 적용

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591574A (en) * 1968-05-29 1971-07-06 American Home Prod Tri-n-phenylglycyl derivatives of insulin
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3704298A (en) * 1971-06-22 1972-11-28 Warner Lambert Co 4-acyloxy-3-(2-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,1-dioxides
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
JPS5714589A (en) * 1980-06-27 1982-01-25 Mitsui Toatsu Chem Inc Benzothiazine derivative, its preparation and drug composition
US4309427A (en) * 1981-01-15 1982-01-05 Pfizer Inc. Benzothiazine dioxide derivatives
IT8219486A0 (it) * 1982-02-05 1982-02-05 Chiesi Farma Spa Nuovi composti ad attivita'antiinfiammatoria, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1206525B (it) * 1982-12-10 1989-04-27 Zionale S R L A Roma Preparato anti-infiammatorio nonsteroideo, per il trattamento delle affezioni artroreumatiche e metodo per la sua preparazione

Also Published As

Publication number Publication date
SE8500889L (sv) 1985-08-24
LU85780A1 (fr) 1985-12-11
FI850742A0 (fi) 1985-02-22
BE901783A (fr) 1985-08-21
PT79988B (en) 1987-02-02
GB2154585A (en) 1985-09-11
DD232045A5 (de) 1986-01-15
IT8519585A0 (it) 1985-02-21
ES540590A0 (es) 1986-04-16
ES8606312A1 (es) 1986-04-16
DE3505576A1 (de) 1985-09-05
AU552478B2 (en) 1986-06-05
GR850442B (ja) 1985-06-19
FI850742L (fi) 1985-08-24
KR850006198A (ko) 1985-10-02
NO850725L (no) 1985-08-26
PL252023A1 (en) 1985-11-05
IT1185514B (it) 1987-11-12
AU3906685A (en) 1985-09-05
NL8500485A (nl) 1985-09-16
SE8500889D0 (sv) 1985-02-22
IL74407A0 (en) 1985-05-31
HUT37616A (en) 1986-01-23
GB8504355D0 (en) 1985-03-20
DK81185D0 (da) 1985-02-22
JPS60184077A (ja) 1985-09-19
PT79988A (en) 1985-03-01
FR2565980A1 (fr) 1985-12-20
DK81185A (da) 1985-09-10

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