ZA849841B - Non-aqueous ivermectin formulation with antiparasitic activity - Google Patents

Non-aqueous ivermectin formulation with antiparasitic activity

Info

Publication number
ZA849841B
ZA849841B ZA849841A ZA849841A ZA849841B ZA 849841 B ZA849841 B ZA 849841B ZA 849841 A ZA849841 A ZA 849841A ZA 849841 A ZA849841 A ZA 849841A ZA 849841 B ZA849841 B ZA 849841B
Authority
ZA
South Africa
Prior art keywords
aqueous
antiparasitic activity
ivermectin formulation
ivermectin
water
Prior art date
Application number
ZA849841A
Other languages
English (en)
Inventor
James B Williams
Russell U Nesbitt
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA849841B publication Critical patent/ZA849841B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA849841A 1983-12-22 1984-12-18 Non-aqueous ivermectin formulation with antiparasitic activity ZA849841B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56414083A 1983-12-22 1983-12-22

Publications (1)

Publication Number Publication Date
ZA849841B true ZA849841B (en) 1986-07-30

Family

ID=24253315

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA849841A ZA849841B (en) 1983-12-22 1984-12-18 Non-aqueous ivermectin formulation with antiparasitic activity

Country Status (17)

Country Link
EP (1) EP0146414B1 (el)
JP (1) JPH0623100B2 (el)
KR (1) KR880002366B1 (el)
AT (1) ATE47522T1 (el)
AU (1) AU560864B2 (el)
CA (1) CA1267844A (el)
DE (1) DE3480263D1 (el)
DK (1) DK164772C (el)
ES (1) ES8608888A1 (el)
GR (1) GR81244B (el)
HK (1) HK5091A (el)
IE (1) IE57681B1 (el)
IL (1) IL73800A (el)
NZ (1) NZ210505A (el)
PT (1) PT79656B (el)
SG (1) SG97890G (el)
ZA (1) ZA849841B (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG48572A3 (en) * 1987-01-23 1991-03-15 Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware Method for preparing of avermectines
US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
GB8803836D0 (en) * 1988-02-18 1988-03-16 Glaxo Group Ltd Compositions
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
US5169846A (en) * 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
GB2275193A (en) * 1993-02-17 1994-08-24 Merck & Co Inc Formulations for the topical delivery of avermectins
BR9406594A (pt) * 1993-05-10 1996-01-02 Merck & Co Inc Formulação tópica e processos para sua preparação e para o tratamento e prevenção de parasitas internos e externos de animais
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen
US6054140A (en) * 1997-03-21 2000-04-25 Biogenesis S.A. Long acting injectable parasiticidal composition and the process for its preparation
AR013202A1 (es) * 1997-07-10 2000-12-13 Biotech Australia Pty Ltd Vacunas no acuosas
GB9816132D0 (en) * 1998-07-24 1998-09-23 Norbrook Lab Ltd Non-aqueous anthelmintic composition
EP1215964A4 (en) * 1999-09-22 2002-11-05 Ashmont Holdings Ltd POUR-ON COMPOSITION FOR SHEEP
JP2001253824A (ja) * 2000-03-14 2001-09-18 Mitsukazu Matsumoto 局所注射用処方剤
GR1003969B (el) * 2001-02-05 2002-08-14 U��-Pharma ����� ������ ������������ ���������� ���� Σταθερα φαρμακευτικα διαλυματα νιμεσουλιδης.
US6627613B2 (en) 2001-07-23 2003-09-30 Michael A. Strobel Application of water and organic solvent soluble ivermectin for topical and oral use
US20050009762A1 (en) 2003-06-06 2005-01-13 Strobel Michael Albert Application of water and organic solvent soluble ivermectin for topical and oral use
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
UY27412A1 (es) * 2002-08-12 2003-06-30 Carlson Internat Inc Un nuevo producto para el combate de garrapatas y el proceso para la prepaacinn.
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
JP4886214B2 (ja) * 2005-05-24 2012-02-29 日本パワーファスニング株式会社 石膏ボード締結用の２条式木ねじ
RU2493825C2 (ru) 2008-10-08 2013-09-27 ВАЙЕТ ЭлЭлСи Бензимидазольные антигельминтные композиции
JP5607114B2 (ja) 2012-06-26 2014-10-15 株式会社トープラ タッピンねじ
EP4337015A1 (en) 2021-05-14 2024-03-20 Syngenta Crop Protection AG Insect, acarina and nematode pest control
WO2022268815A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144352A (en) * 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4130651A (en) * 1978-03-31 1978-12-19 American Cyanamid Company Butamisole injectable formulations having improved margin of safety in dogs
OA06863A (fr) * 1980-08-04 1983-02-28 Merck & Co Inc Solubilisation de l'invermectine dans l'eau.
US4430329A (en) * 1982-05-17 1984-02-07 Merck & Co., Inc. Synergistic treatment of adult canine heartworm with thiacetarsamide and ivermectin

Also Published As

Publication number Publication date
DK619784D0 (da) 1984-12-21
GR81244B (en) 1985-04-16
DK164772B (da) 1992-08-17
KR880002366B1 (ko) 1988-11-03
AU560864B2 (en) 1987-04-16
DE3480263D1 (en) 1989-11-30
JPS60169415A (ja) 1985-09-02
HK5091A (en) 1991-01-18
PT79656A (en) 1985-01-01
AU3702484A (en) 1985-07-04
CA1267844A (en) 1990-04-17
EP0146414A2 (en) 1985-06-26
EP0146414B1 (en) 1989-10-25
ES8608888A1 (es) 1986-07-16
IL73800A (en) 1987-11-30
IE843221L (en) 1985-06-22
SG97890G (en) 1991-02-14
IE57681B1 (en) 1993-02-24
JPH0623100B2 (ja) 1994-03-30
ATE47522T1 (de) 1989-11-15
IL73800A0 (en) 1985-03-31
KR850004391A (ko) 1985-07-15
ES538750A0 (es) 1986-07-16
DK619784A (da) 1985-06-23
PT79656B (en) 1987-01-16
DK164772C (da) 1993-01-04
NZ210505A (en) 1988-06-30
EP0146414A3 (en) 1986-12-10

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