ZA845490B - Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof - Google Patents

Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof

Info

Publication number
ZA845490B
ZA845490B ZA845490A ZA845490A ZA845490B ZA 845490 B ZA845490 B ZA 845490B ZA 845490 A ZA845490 A ZA 845490A ZA 845490 A ZA845490 A ZA 845490A ZA 845490 B ZA845490 B ZA 845490B
Authority
ZA
South Africa
Prior art keywords
group
substituted
alkyl
pharmaceutical compositions
processes
Prior art date
Application number
ZA845490A
Other languages
English (en)
Inventor
Giuseppe Dr Bietti
Enzo Dr Cereda
Arturo Dr Donetti
Antonio Prof Giachetti
Ferdinando Dr Pagani
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of ZA845490B publication Critical patent/ZA845490B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment Of Sludge (AREA)
  • Processing Of Solid Wastes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA845490A 1983-07-18 1984-07-17 Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof ZA845490B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Publications (1)

Publication Number Publication Date
ZA845490B true ZA845490B (en) 1986-03-26

Family

ID=11191639

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845490A ZA845490B (en) 1983-07-18 1984-07-17 Imidazole derivatives,processes for their preparation and pharmaceutical compositions thereof

Country Status (28)

Country Link
US (1) US4649150A (pl)
EP (1) EP0131973B1 (pl)
JP (1) JPS6038367A (pl)
KR (1) KR910000661B1 (pl)
AT (1) ATE45149T1 (pl)
AU (1) AU565292B2 (pl)
CA (1) CA1257274A (pl)
CS (1) CS244141B2 (pl)
DD (1) DD232696A5 (pl)
DE (1) DE3479212D1 (pl)
DK (1) DK350084A (pl)
ES (2) ES8601910A1 (pl)
FI (1) FI842432A (pl)
GB (1) GB2149395B (pl)
GR (1) GR79981B (pl)
HK (1) HK74287A (pl)
HU (1) HU193292B (pl)
IL (1) IL72417A (pl)
IT (1) IT1206498B (pl)
NO (1) NO162857C (pl)
NZ (1) NZ208920A (pl)
PH (1) PH21566A (pl)
PL (2) PL143303B1 (pl)
PT (1) PT78935B (pl)
SG (1) SG48687G (pl)
SU (2) SU1322979A3 (pl)
YU (2) YU43367B (pl)
ZA (1) ZA845490B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
BR9810651A (pt) 1997-07-03 2000-10-03 Neurogen Corp Certos derivados de diarilimidazol; uma nova classe de ligantes npy especìficos
US6887870B1 (en) 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
NZ519272A (en) 1999-12-16 2004-02-27 Schering Corp Substituted imidazole neuropeptide Y Y5 receptor antagonists
FR2917087B1 (fr) 2007-06-05 2012-09-21 Galderma Res & Dev Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.

Also Published As

Publication number Publication date
HUT34959A (en) 1985-05-28
DD232696A5 (de) 1986-02-05
IL72417A0 (en) 1984-11-30
IL72417A (en) 1988-03-31
ES8505962A1 (es) 1985-06-16
DE3479212D1 (en) 1989-09-07
YU112686A (en) 1987-12-31
JPS6038367A (ja) 1985-02-27
PT78935A (de) 1984-08-01
IT1206498B (it) 1989-04-27
DK350084D0 (da) 1984-07-17
PL143732B1 (en) 1988-03-31
ATE45149T1 (de) 1989-08-15
KR850001173A (ko) 1985-03-16
PL248779A1 (en) 1985-12-03
AU3080084A (en) 1985-01-24
NZ208920A (en) 1987-03-31
NO162857B (no) 1989-11-20
US4649150A (en) 1987-03-10
ES534376A0 (es) 1985-11-01
GB2149395A (en) 1985-06-12
FI842432A0 (fi) 1984-06-15
YU43701B (en) 1989-10-31
AU565292B2 (en) 1987-09-10
CS244141B2 (en) 1986-07-17
SU1313345A3 (ru) 1987-05-23
SG48687G (en) 1987-07-24
EP0131973B1 (en) 1989-08-02
YU43367B (en) 1989-06-30
PL254625A1 (en) 1986-05-06
ES534375A0 (es) 1985-06-16
YU115484A (en) 1986-12-31
GR79981B (pl) 1984-10-31
HK74287A (en) 1987-10-23
ES8601910A1 (es) 1985-11-01
PL143303B1 (en) 1988-02-29
CA1257274A (en) 1989-07-11
IT8322110A0 (it) 1983-07-18
CS554284A2 (en) 1985-08-15
NO162857C (no) 1990-02-28
EP0131973A1 (en) 1985-01-23
HU193292B (en) 1987-09-28
GB2149395B (en) 1986-11-26
PH21566A (en) 1987-12-11
KR910000661B1 (ko) 1991-01-31
DK350084A (da) 1985-01-19
FI842432A (fi) 1985-01-19
GB8418149D0 (en) 1984-08-22
SU1322979A3 (ru) 1987-07-07
PT78935B (de) 1986-10-23
NO842921L (no) 1985-01-21

Similar Documents

Publication Publication Date Title
DE3479212D1 (en) New amidine derivatives of 2-substituted 4-phenilimidazole
AU562246B2 (en) Hetero substituted phenyl formamidines