ZA844968B - 2-piperazino-pteridines - Google Patents

2-piperazino-pteridines

Info

Publication number
ZA844968B
ZA844968B ZA844968A ZA844968A ZA844968B ZA 844968 B ZA844968 B ZA 844968B ZA 844968 A ZA844968 A ZA 844968A ZA 844968 A ZA844968 A ZA 844968A ZA 844968 B ZA844968 B ZA 844968B
Authority
ZA
South Africa
Prior art keywords
group
thiomorpholino
piperidino
morpholino
pteridines
Prior art date
Application number
ZA844968A
Other languages
English (en)
Inventor
Josef Dr Roch
Josef Dr Nickl
Erich Dr Mueller
Berthold Dr Narr
Johannes Dr Weisenberger
Rainer Dr Zimmermann
Walter Dr Haarmann
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA844968B publication Critical patent/ZA844968B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA844968A 1983-07-02 1984-06-29 2-piperazino-pteridines ZA844968B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833323932 DE3323932A1 (de) 1983-07-02 1983-07-02 Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA844968B true ZA844968B (en) 1986-03-26

Family

ID=6203017

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA844968A ZA844968B (en) 1983-07-02 1984-06-29 2-piperazino-pteridines

Country Status (17)

Country Link
EP (1) EP0134922B1 (xx)
JP (1) JPS6025991A (xx)
AT (1) ATE39253T1 (xx)
AU (1) AU565105B2 (xx)
CA (1) CA1233179A (xx)
DD (1) DD229990A5 (xx)
DE (2) DE3323932A1 (xx)
DK (1) DK159113C (xx)
ES (2) ES533298A0 (xx)
FI (1) FI80454C (xx)
GB (1) GB2143232B (xx)
HU (1) HU190932B (xx)
IL (1) IL72265A (xx)
NO (1) NO160920C (xx)
NZ (1) NZ208725A (xx)
PH (1) PH22493A (xx)
ZA (1) ZA844968B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445298A1 (de) * 1984-12-12 1986-06-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE3540952C2 (de) * 1985-11-19 1997-08-14 Thomae Gmbh Dr K 2-Piperazino-pteridine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
DE602004009696T2 (de) * 2003-08-29 2008-08-28 4 Aza Ip Nv Immunosuppressive wirkungen von pteridinderivativen
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
DE102004057645A1 (de) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
ATE549338T1 (de) * 2006-05-24 2012-03-15 Boehringer Ingelheim Int Substituierte pteridine, die mit einem viergliedrigen heterocyclus substituiert sind
WO2007135026A2 (de) 2006-05-24 2007-11-29 Boehringer Ingelheim International Gmbh Substituierte pteridine als therapeutika
US20090318456A1 (en) * 2006-07-06 2009-12-24 Gilead Sciences, Inc. Substituted pteridines for the treatment and prevention of viral infections
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
KR101756050B1 (ko) 2015-03-04 2017-07-07 길리애드 사이언시즈, 인코포레이티드 톨 유사 수용체 조정제 화합물
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
SI3507276T1 (sl) 2016-09-02 2022-01-31 Gilead Sciences, Inc. Spojine modulatorja toličnih receptorjev
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2940972A (en) * 1957-06-27 1960-06-14 Thomae Gmbh Dr K Tri-and tetra-substituted pteridine derivatives
FR1352111A (fr) * 1962-01-25 1964-02-14 Lumiere Lab Triamino ptéridines et leur préparation

Also Published As

Publication number Publication date
DK159113C (da) 1991-02-18
CA1233179A (en) 1988-02-23
ES537785A0 (es) 1985-10-16
DD229990A5 (de) 1985-11-20
FI842622A (fi) 1985-01-03
DE3323932A1 (de) 1985-01-10
IL72265A0 (en) 1984-10-31
FI842622A0 (fi) 1984-06-29
AU565105B2 (en) 1987-09-03
GB2143232B (en) 1986-11-05
ES8601205A1 (es) 1985-10-16
EP0134922A1 (de) 1985-03-27
JPS6025991A (ja) 1985-02-08
DK159113B (da) 1990-09-03
NZ208725A (en) 1988-10-28
DK316284A (da) 1985-01-03
HUT34487A (en) 1985-03-28
DK316284D0 (da) 1984-06-28
GB8416682D0 (en) 1984-08-01
NO160920B (no) 1989-03-06
NO842631L (no) 1985-01-03
ES8503352A1 (es) 1985-02-16
NO160920C (no) 1989-06-14
PH22493A (en) 1988-09-12
FI80454C (fi) 1990-06-11
FI80454B (fi) 1990-02-28
AU3009284A (en) 1985-01-03
ATE39253T1 (de) 1988-12-15
HU190932B (en) 1986-12-28
DE3475620D1 (en) 1989-01-19
EP0134922B1 (de) 1988-12-14
IL72265A (en) 1987-08-31
GB2143232A (en) 1985-02-06
ES533298A0 (es) 1985-02-16

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