ZA842176B - Xylane sulfates,process for their preparation,and anti-thrombosis and hypolipemic activity thereof - Google Patents

Xylane sulfates,process for their preparation,and anti-thrombosis and hypolipemic activity thereof

Info

Publication number
ZA842176B
ZA842176B ZA842176A ZA842176A ZA842176B ZA 842176 B ZA842176 B ZA 842176B ZA 842176 A ZA842176 A ZA 842176A ZA 842176 A ZA842176 A ZA 842176A ZA 842176 B ZA842176 B ZA 842176B
Authority
ZA
South Africa
Prior art keywords
xylane
thrombosis
sulfates
preparation
hypolipemic activity
Prior art date
Application number
ZA842176A
Other languages
English (en)
Inventor
Jean-Pierre Maffrand
Eric Vallee
Jean-Marie Pereillo
Alain Bayol
Jacqueline Lansen
Original Assignee
Sanofi Sa
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa, Anic Spa filed Critical Sanofi Sa
Publication of ZA842176B publication Critical patent/ZA842176B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/14—Hemicellulose; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
ZA842176A 1983-03-24 1984-03-23 Xylane sulfates,process for their preparation,and anti-thrombosis and hypolipemic activity thereof ZA842176B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8305170A FR2543145B1 (fr) 1983-03-24 1983-03-24 Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante

Publications (1)

Publication Number Publication Date
ZA842176B true ZA842176B (en) 1984-10-31

Family

ID=9287351

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA842176A ZA842176B (en) 1983-03-24 1984-03-23 Xylane sulfates,process for their preparation,and anti-thrombosis and hypolipemic activity thereof

Country Status (16)

Country Link
US (1) US4699900A (el)
EP (1) EP0125152B1 (el)
JP (1) JPS6063203A (el)
KR (1) KR860001394B1 (el)
AT (1) ATE24520T1 (el)
AU (1) AU561588B2 (el)
CA (1) CA1221090A (el)
DE (1) DE3461808D1 (el)
DK (1) DK55784A (el)
ES (1) ES8500962A1 (el)
FR (1) FR2543145B1 (el)
GR (1) GR79831B (el)
IL (1) IL70846A0 (el)
NZ (1) NZ207622A (el)
PT (1) PT78179B (el)
ZA (1) ZA842176B (el)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante
FR2572731B1 (fr) * 1984-11-07 1987-03-06 Sanofi Sa Nouveaux sulfates de xylanes de bas poids moleculaires, leur procede de preparation et leur activite antithrombotique et hypolipemiante par voie orale
FR2574663B1 (fr) * 1984-12-17 1987-01-16 Sanofi Sa Nouvelle composition therapeutique a activite antithrombotique et hypolipemiante a base de xylanes et d'un acide organique
US4820693A (en) * 1986-05-22 1989-04-11 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US4966890A (en) * 1986-04-04 1990-10-30 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
DE3917982A1 (de) * 1989-06-02 1990-12-06 Behringwerke Ag Verwendung von xylanpolyhydrogensulfaten zur therapie von zellproliferations-bedingten erkrankungen
FR2655267B1 (fr) * 1989-12-04 1992-04-03 Roussel Uclaf Nouveau derive sulfate du galactanne extrait de klebsiella, procede de preparation, application a titre de medicaments et compositions pharmaceutiques le renfermant.
US5141928B1 (en) * 1989-12-20 1995-11-14 Brujo Inc Ophthalmic medication
US5382570A (en) * 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
US5378829A (en) * 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5668274A (en) * 1991-04-23 1997-09-16 Akzo Nobel N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6451771B1 (en) 1999-02-12 2002-09-17 Nutramax Laboratories, Inc. Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals
US20070141181A1 (en) 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6797289B2 (en) 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
ES2251289B1 (es) * 2004-02-27 2007-07-01 Bioiberica, S.A. Nuevo uso terapeutico de un grupo de polisacaridos sulfatados.
WO2009047699A1 (en) * 2007-10-10 2009-04-16 Alembic Limited An improved process for the preparation of an amorphous form of pentosan polysulfate or salts thereof
AU2008100730B4 (en) * 2008-07-04 2008-10-02 Parnell Technologies Pty Ltd Sulfated polysaccharide compound for clinical use and the preparation thereof
US8871741B2 (en) * 2010-01-15 2014-10-28 Icahn School Of Medicine At Mount Sinai Inhibition of TNF-α induced activation of NFKB by pentosan polysulfate
WO2012101544A1 (en) * 2011-01-29 2012-08-02 Alembic Pharmaceuticals Limited An improved process for the preparation of pentosan polysulfate or salts thereof
WO2012114349A1 (en) * 2011-02-23 2012-08-30 Cadila Healthcare Limited An improved process for the preparation of pentosan polysulfate sodium
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
WO2018043666A1 (ja) 2016-08-31 2018-03-08 王子ホールディングス株式会社 酸性キシロオリゴ糖の製造方法
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
SG11201911318SA (en) 2017-05-31 2020-01-30 Oji Holdings Corp Moisturizing topical preparation
BR112020004787A2 (pt) * 2017-09-12 2020-09-24 Oji Holdings Corporation polissulfato de pentosano, composição farmacêutica, anticoagulante, e, método para produzir polissulfato de pentosano
PL3730521T3 (pl) * 2017-12-20 2023-10-09 Oji Holdings Corporation Polisiarczan pentozanu i lek zawierający polisiarczan pentozanu

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH290145A (de) * 1944-06-13 1953-04-15 Kaulla Kurt Nikolai Dr Med Von Verfahren zur Herstellung von Schwefelsäureestern des Xylans.
FR1050576A (fr) * 1951-02-06 1954-01-08 Wander Ag Dr A Procédé pour la préparation de sels alcalins de l'ester sulfurique du xylane
US3290263A (en) * 1962-08-02 1966-12-06 Colonial Sugar Refining Co Process of reacting sugars with reagents wherein the sugar is dissolved in monohydric alcohols containing grouping
ES343957A1 (es) * 1967-08-09 1968-10-01 Rocador Sa Procedimiento de obtencion de polisacaridos sulfatados an- tilipemicos activos por via oral.
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
US4301153A (en) * 1977-03-21 1981-11-17 Riker Laboratories, Inc. Heparin preparation
US4122250A (en) * 1977-08-22 1978-10-24 Gottfried Schmer Separation of high-activity heparin by affinity chromatography
US4221907A (en) * 1979-07-09 1980-09-09 American Cyanamid Company Substituted O-α-D and O-β-D-multi-galactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6 α-D-glucopyranoses
DE2945595A1 (de) * 1979-11-12 1981-05-21 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur herstellung von niedermolekularem heparin bzw. seinen salzen
US4281108A (en) * 1980-01-28 1981-07-28 Hepar Industries, Inc. Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante

Also Published As

Publication number Publication date
PT78179A (fr) 1984-04-01
NZ207622A (en) 1986-08-08
DE3461808D1 (en) 1987-02-05
DK55784A (da) 1984-09-25
DK55784D0 (da) 1984-02-08
KR840008376A (ko) 1984-12-14
PT78179B (fr) 1986-04-24
AU2441284A (en) 1984-09-27
AU561588B2 (en) 1987-05-14
US4699900A (en) 1987-10-13
IL70846A0 (en) 1984-05-31
KR860001394B1 (ko) 1986-09-22
FR2543145B1 (fr) 1986-10-17
GR79831B (el) 1984-10-31
ATE24520T1 (de) 1987-01-15
EP0125152A1 (fr) 1984-11-14
ES530266A0 (es) 1984-11-01
CA1221090A (fr) 1987-04-28
JPS6063203A (ja) 1985-04-11
ES8500962A1 (es) 1984-11-01
FR2543145A1 (fr) 1984-09-28
EP0125152B1 (fr) 1986-12-30

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