ZA827063B - Pharmaceutical compositions having a peripheral antagonistic action with respect to opiates - Google Patents

Pharmaceutical compositions having a peripheral antagonistic action with respect to opiates

Info

Publication number
ZA827063B
ZA827063B ZA827063A ZA827063A ZA827063B ZA 827063 B ZA827063 B ZA 827063B ZA 827063 A ZA827063 A ZA 827063A ZA 827063 A ZA827063 A ZA 827063A ZA 827063 B ZA827063 B ZA 827063B
Authority
ZA
South Africa
Prior art keywords
opiates
respect
antagonistic action
pharmaceutical compositions
peripheral antagonistic
Prior art date
Application number
ZA827063A
Other languages
English (en)
Inventor
Antonina Giudice
Claude Moulineau
Luciano Manara
Paolo Carminati
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA827063B publication Critical patent/ZA827063B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ZA827063A 1981-10-19 1982-09-27 Pharmaceutical compositions having a peripheral antagonistic action with respect to opiates ZA827063B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8119607A FR2514644A1 (fr) 1981-10-19 1981-10-19 Composition pharmaceutique a action antagoniste peripherique des opiaces

Publications (1)

Publication Number Publication Date
ZA827063B true ZA827063B (en) 1983-07-27

Family

ID=9263165

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA827063A ZA827063B (en) 1981-10-19 1982-09-27 Pharmaceutical compositions having a peripheral antagonistic action with respect to opiates

Country Status (10)

Country Link
US (1) US4489079A (enExample)
EP (1) EP0077723B1 (enExample)
JP (1) JPS5874608A (enExample)
AT (1) ATE17942T1 (enExample)
AU (1) AU559451B2 (enExample)
DE (1) DE3269082D1 (enExample)
FR (1) FR2514644A1 (enExample)
IL (1) IL66853A (enExample)
NZ (1) NZ202210A (enExample)
ZA (1) ZA827063B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547820B1 (fr) * 1983-06-24 1986-04-18 Midy Spa Antagonistes peripheriques des opiaces
US5624958A (en) * 1987-12-31 1997-04-29 Isaacs; Charles E. Disinfecting contact lenses
US5552406A (en) * 1994-06-17 1996-09-03 The Mclean Hospital Corporation Method for treating pain and brain perfusion abnormalities using mixed opioid agonist-antagonists
DE19752080A1 (de) * 1997-11-25 1999-07-29 Karlsruhe Forschzent Verfahren zur Herstellung eines mehrkomponentigen, oxidischen Keramikpulvers
US6469030B2 (en) * 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
EP1244448B1 (en) * 1999-11-29 2009-05-27 Adolor Corporation Novel methods for the treatment and prevention of ileus
US7056500B2 (en) * 2001-10-18 2006-06-06 Nektar Therapeutics Al, Corporation Polymer conjugates of opioid antagonists
US20050191340A1 (en) * 2002-08-09 2005-09-01 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
CN1925875A (zh) * 2003-12-16 2007-03-07 尼克塔治疗亚拉巴马公司 化学改性的小分子
WO2009023567A1 (en) 2007-08-09 2009-02-19 Rensselaer Polytechnic Institute Quaternary opioid carboxamides
HUE043963T2 (hu) 2009-12-04 2019-09-30 Alkermes Pharma Ireland Ltd Morfinán származékok gyógyszer-túladagolás kezelésére
WO2011119605A2 (en) 2010-03-22 2011-09-29 Rensselaer Polytechnic Institute Carboxamide biosiosteres of opiates
EP2608670B1 (en) 2010-08-23 2018-10-31 Alkermes Pharma Ireland Limited Methods for treating antipsychotic-induced weight gain
CA2840643C (en) 2011-06-29 2017-11-21 Alkermes, Inc. Peripherally acting opioid compounds
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
ES2770978T3 (es) 2013-05-24 2020-07-06 Alkermes Pharma Ireland Ltd Análogos de morfanos y morfinanos y métodos de uso
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4176186A (en) * 1978-07-28 1979-11-27 Boehringer Ingelheim Gmbh Quaternary derivatives of noroxymorphone which relieve intestinal immobility

Also Published As

Publication number Publication date
US4489079A (en) 1984-12-18
JPS5874608A (ja) 1983-05-06
IL66853A0 (en) 1982-12-31
NZ202210A (en) 1985-03-20
EP0077723A1 (fr) 1983-04-27
EP0077723B1 (fr) 1986-02-12
FR2514644A1 (fr) 1983-04-22
ATE17942T1 (de) 1986-02-15
AU559451B2 (en) 1987-03-12
DE3269082D1 (en) 1986-03-27
FR2514644B1 (enExample) 1984-04-20
IL66853A (en) 1985-08-30
AU8892282A (en) 1983-04-28

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