ES8602744A1 - Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico - Google Patents

Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico

Info

Publication number
ES8602744A1
ES8602744A1 ES541911A ES541911A ES8602744A1 ES 8602744 A1 ES8602744 A1 ES 8602744A1 ES 541911 A ES541911 A ES 541911A ES 541911 A ES541911 A ES 541911A ES 8602744 A1 ES8602744 A1 ES 8602744A1
Authority
ES
Spain
Prior art keywords
alkylaminopropionyl
thiophenes
thiophene ring
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541911A
Other languages
English (en)
Other versions
ES541911A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES541911A priority Critical patent/ES8602744A1/es
Publication of ES541911A0 publication Critical patent/ES541911A0/es
Publication of ES8602744A1 publication Critical patent/ES8602744A1/es
Priority to CA000503190A priority patent/CA1267653A/en
Priority to ZA861848A priority patent/ZA861848B/xx
Priority to EP86103651A priority patent/EP0196001B1/en
Priority to DE8686103651T priority patent/DE3661917D1/de
Priority to JP61061932A priority patent/JPS61243076A/ja
Priority to PH33556A priority patent/PH22262A/en
Priority to US06/936,706 priority patent/US4719225A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE NUEVOS DERIVADOS A A-(ALQUILAMINAPROPIONIL)-TIOFENO SUSTITUIDOS EN EL ANILLO TIOFENICO. CONSISTE EN LA REACCION DE LOS A-(BROMOPROPIONIL)-TIOFENOS DE FORMULA GENERAL (II) CON LAS AMINAS DE FORMULA GENERAL (III), OBTENIENDOSE ASI LOS NUEVOS DERIVADOS DE A-(ALQUILAMINOPROPIONIL)-TIOFENO SUSTITUIDOS EN EL ANILLO TIOFENICO DE FORMULA GENERAL (I) DONDE X ES UN RADICAL DISTINTO DE HIDROGENO, PREFERENTEMENTE CLORO, Y R ES UN RADICAL ALQUILO, PREFERENTEMENTE RAMIFICADO, PUDIENDOSE FORMAR SUS SALES FARMACEUTICAMENTE ACEPTABLES, POR TRATAMIENTO CON LOS ACIDOS CORRESPONDIENTES. DE APLICACION FARMACOLOGICA POR SU EFECTO ANTIDEPRESIVO.
ES541911A 1985-03-20 1985-03-20 Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico Expired ES8602744A1 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES541911A ES8602744A1 (es) 1985-03-20 1985-03-20 Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico
CA000503190A CA1267653A (en) 1985-03-20 1986-03-04 THIOPHENE RING-SUBTITUTED .alpha.-(ALKYLAMINOPROPIONYL)- THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
ZA861848A ZA861848B (en) 1985-03-20 1986-03-12 Thiophene ring-substituted alpha-(alkylaminopropionyl)-thiophene derivatives and process for their production
EP86103651A EP0196001B1 (en) 1985-03-20 1986-03-18 Thiophene ring-substituted alpha-(alkylaminopropionyl)-thiophene derivatives, a process for preparing them and pharmaceutical compositions containing them
DE8686103651T DE3661917D1 (en) 1985-03-20 1986-03-18 Thiophene ring-substituted alpha-(alkylaminopropionyl)-thiophene derivatives, a process for preparing them and pharmaceutical compositions containing them
JP61061932A JPS61243076A (ja) 1985-03-20 1986-03-19 新規チオフエン誘導体
PH33556A PH22262A (en) 1985-03-20 1986-03-19 Thiophene ring substituted l-(alkylaminopropionyl)-thiophenes
US06/936,706 US4719225A (en) 1985-03-20 1986-12-01 Thiophene ring-substituted α-(alkylaminopropionyl)-thiophenes and the method for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES541911A ES8602744A1 (es) 1985-03-20 1985-03-20 Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico

Publications (2)

Publication Number Publication Date
ES541911A0 ES541911A0 (es) 1985-12-01
ES8602744A1 true ES8602744A1 (es) 1985-12-01

Family

ID=8488959

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541911A Expired ES8602744A1 (es) 1985-03-20 1985-03-20 Procedimiento de obtencion de nuevos derivados -(alquilamino-propionil)-tiofeno sustituidos en el anillo tiofenico

Country Status (4)

Country Link
US (1) US4719225A (es)
JP (1) JPS61243076A (es)
ES (1) ES8602744A1 (es)
ZA (1) ZA861848B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES556311A0 (es) * 1986-06-03 1987-08-01 Ferrer Int Mejoras en el objeto de la patente de invencion n.541.911 por procedimiento de obtencion de nuevos derivados de alfa-(alquilaminopropionil)-tiofeno sustituidos en el anillo tiofenico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1217396B (de) * 1963-07-04 1966-05-26 Laboratorie Roger Bellon, Neuilly-sur-Seine (Frankreich) Verfahren zur Herstellung von 1 - (Thienyl-21) - l-oxo-2-amino-propanen
US3193551A (en) * 1963-08-30 1965-07-06 Passedouet Andre Henri Preparation of 1-alpha-thienyl-phenylcarbinols
US3505338A (en) * 1966-11-25 1970-04-07 American Cyanamid Co Thiophenecarbonylalkylene-diamines

Also Published As

Publication number Publication date
ES541911A0 (es) 1985-12-01
JPH0310624B2 (es) 1991-02-14
JPS61243076A (ja) 1986-10-29
US4719225A (en) 1988-01-12
ZA861848B (en) 1987-01-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103