ZA826252B - Tricyclic ethers,their preparation and the pharmaceutical compositions containing them - Google Patents
Tricyclic ethers,their preparation and the pharmaceutical compositions containing themInfo
- Publication number
- ZA826252B ZA826252B ZA826252A ZA826252A ZA826252B ZA 826252 B ZA826252 B ZA 826252B ZA 826252 A ZA826252 A ZA 826252A ZA 826252 A ZA826252 A ZA 826252A ZA 826252 B ZA826252 B ZA 826252B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- lower alkyl
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 150000002170 ethers Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/18—[b, e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8116347A FR2512024A1 (fr) | 1981-08-27 | 1981-08-27 | Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA826252B true ZA826252B (en) | 1983-07-27 |
Family
ID=9261704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA826252A ZA826252B (en) | 1981-08-27 | 1982-08-26 | Tricyclic ethers,their preparation and the pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4496557A (OSRAM) |
| EP (1) | EP0074304B1 (OSRAM) |
| JP (1) | JPS5874673A (OSRAM) |
| AT (1) | ATE12497T1 (OSRAM) |
| AU (1) | AU8773082A (OSRAM) |
| CA (1) | CA1227481A (OSRAM) |
| DE (1) | DE3262880D1 (OSRAM) |
| ES (1) | ES515232A0 (OSRAM) |
| FR (1) | FR2512024A1 (OSRAM) |
| GR (1) | GR77595B (OSRAM) |
| IL (1) | IL66650A (OSRAM) |
| NZ (1) | NZ201740A (OSRAM) |
| PT (1) | PT75471B (OSRAM) |
| ZA (1) | ZA826252B (OSRAM) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8500273D0 (sv) * | 1985-01-22 | 1985-01-22 | Leo Ab | Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder |
| EP0332246A1 (en) * | 1988-03-11 | 1989-09-13 | Akzo N.V. | Tricyclic amine derivatives |
| US5180736A (en) * | 1989-03-23 | 1993-01-19 | Warner-Lambert Company | Polycyclic amines useful as cerebrovascular agents |
| US5260319A (en) * | 1989-12-26 | 1993-11-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Thienobenzoxepins and naphthothiophenes |
| US5006536A (en) * | 1989-12-26 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals Inc. | Thienobenzoxepins and analgesic compositions thereof |
| US5574173A (en) * | 1993-12-06 | 1996-11-12 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
| DE59607332D1 (de) * | 1995-02-08 | 2001-08-30 | Novartis Ag | Antineurodegenerativ wirksame 10-Aminoaliphatyl-dibenz- b,f oxepine |
| US5698551A (en) * | 1995-04-07 | 1997-12-16 | Novo Nordisk A/S | Heterocyclic compounds |
| US10638994B2 (en) | 2002-11-27 | 2020-05-05 | Hologic, Inc. | X-ray mammography with tomosynthesis |
| US7123684B2 (en) | 2002-11-27 | 2006-10-17 | Hologic, Inc. | Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing |
| US8571289B2 (en) | 2002-11-27 | 2013-10-29 | Hologic, Inc. | System and method for generating a 2D image from a tomosynthesis data set |
| US7616801B2 (en) | 2002-11-27 | 2009-11-10 | Hologic, Inc. | Image handling and display in x-ray mammography and tomosynthesis |
| US7577282B2 (en) * | 2002-11-27 | 2009-08-18 | Hologic, Inc. | Image handling and display in X-ray mammography and tomosynthesis |
| US8565372B2 (en) | 2003-11-26 | 2013-10-22 | Hologic, Inc | System and method for low dose tomosynthesis |
| US8768026B2 (en) | 2003-11-26 | 2014-07-01 | Hologic, Inc. | X-ray imaging with x-ray markers that provide adjunct information but preserve image quality |
| US7662082B2 (en) | 2004-11-05 | 2010-02-16 | Theragenics Corporation | Expandable brachytherapy device |
| US7702142B2 (en) | 2004-11-15 | 2010-04-20 | Hologic, Inc. | Matching geometry generation and display of mammograms and tomosynthesis images |
| US7869563B2 (en) * | 2004-11-26 | 2011-01-11 | Hologic, Inc. | Integrated multi-mode mammography/tomosynthesis x-ray system and method |
| US7245694B2 (en) * | 2005-08-15 | 2007-07-17 | Hologic, Inc. | X-ray mammography/tomosynthesis of patient's breast |
| US8079946B2 (en) | 2005-11-18 | 2011-12-20 | Senorx, Inc. | Asymmetrical irradiation of a body cavity |
| JP5554927B2 (ja) | 2006-02-15 | 2014-07-23 | ホロジック， インコーポレイテッド | トモシンセシスシステムを使用した乳房バイオプシおよびニードル位置特定 |
| US7630533B2 (en) | 2007-09-20 | 2009-12-08 | Hologic, Inc. | Breast tomosynthesis with display of highlighted suspected calcifications |
| US7991106B2 (en) | 2008-08-29 | 2011-08-02 | Hologic, Inc. | Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles |
| CN102196772A (zh) | 2008-09-04 | 2011-09-21 | 霍罗吉克公司 | 集成多模式乳房x射线照相术/体层合成x射线系统和方法 |
| US9579524B2 (en) | 2009-02-11 | 2017-02-28 | Hologic, Inc. | Flexible multi-lumen brachytherapy device |
| US9248311B2 (en) | 2009-02-11 | 2016-02-02 | Hologic, Inc. | System and method for modifying a flexibility of a brachythereapy catheter |
| US8170320B2 (en) * | 2009-03-03 | 2012-05-01 | Hologic, Inc. | Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly |
| US10207126B2 (en) | 2009-05-11 | 2019-02-19 | Cytyc Corporation | Lumen visualization and identification system for multi-lumen balloon catheter |
| CN106420066B (zh) | 2009-10-08 | 2020-08-25 | 霍罗吉克公司 | 将穿刺活检组件引导到目标位置的方法及x射线成像系统 |
| US9352172B2 (en) | 2010-09-30 | 2016-05-31 | Hologic, Inc. | Using a guide member to facilitate brachytherapy device swap |
| JP5955327B2 (ja) | 2010-10-05 | 2016-07-20 | ホロジック, インコーポレイテッドHologic, Inc. | 直立した患者の乳房をｘ線で撮像するシステム及び方法 |
| WO2012071429A1 (en) | 2010-11-26 | 2012-05-31 | Hologic, Inc. | User interface for medical image review workstation |
| US10342992B2 (en) | 2011-01-06 | 2019-07-09 | Hologic, Inc. | Orienting a brachytherapy applicator |
| WO2012122399A1 (en) | 2011-03-08 | 2012-09-13 | Hologic, Inc. | System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy |
| US11259759B2 (en) | 2011-11-18 | 2022-03-01 | Hologic Inc. | X-ray mammography and/or breast tomosynthesis using a compression paddle |
| JP2014534042A (ja) | 2011-11-27 | 2014-12-18 | ホロジック, インコーポレイテッドHologic, Inc. | マンモグラフィーおよび／またはトモシンセシス画像データを使用して２ｄ画像を生成するためのシステムおよび方法 |
| EP3315072B1 (en) | 2012-02-13 | 2020-04-29 | Hologic, Inc. | System and method for navigating a tomosynthesis stack using synthesized image data |
| JP6388347B2 (ja) | 2013-03-15 | 2018-09-12 | ホロジック, インコーポレイテッドHologic, Inc. | 腹臥位におけるトモシンセシス誘導生検 |
| JP6392309B2 (ja) | 2013-03-15 | 2018-09-19 | ホロジック インコーポレイティッド | 自動合焦を含む、トモシンセシススタックをナビゲートするためのシステム |
| KR102264462B1 (ko) | 2013-10-09 | 2021-06-15 | 홀로직, 인크. | 편평화된 유방의 두께 방향을 포함하는 공간 해상도를 향상시키는 x선 유방 영상합성 |
| JP2016533803A (ja) | 2013-10-24 | 2016-11-04 | アンドリュー ピー． スミス， | Ｘ線誘導胸部生検をナビゲートするためのシステムおよび方法 |
| CA2937379C (en) | 2014-02-28 | 2022-08-09 | Hologic, Inc. | System and method for generating and displaying tomosynthesis image slabs |
| WO2016073445A1 (en) | 2014-11-07 | 2016-05-12 | Hologic, Inc. | Pivoting paddle apparatus for mammography/tomosynthesis x-ray system |
| WO2017185028A1 (en) | 2016-04-22 | 2017-10-26 | Hologic, Inc. | Tomosynthesis with shifting focal spot x-ray system using an addressable array |
| EP3868302B1 (en) | 2016-11-08 | 2023-12-06 | Hologic, Inc. | Imaging with curved compression elements |
| WO2018183549A1 (en) | 2017-03-30 | 2018-10-04 | Hologic, Inc. | System and method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement |
| US11445993B2 (en) | 2017-03-30 | 2022-09-20 | Hologic, Inc. | System and method for targeted object enhancement to generate synthetic breast tissue images |
| US11399790B2 (en) | 2017-03-30 | 2022-08-02 | Hologic, Inc. | System and method for hierarchical multi-level feature image synthesis and representation |
| EP3641635A4 (en) | 2017-06-20 | 2021-04-07 | Hologic, Inc. | DYNAMIC SELF-LEARNING MEDICAL IMAGING PROCESS AND SYSTEM |
| AU2018313272B2 (en) | 2017-08-11 | 2024-01-11 | Hologic, Inc. | Breast compression paddle with access corners |
| WO2019033022A1 (en) | 2017-08-11 | 2019-02-14 | Hologic, Inc. | BREAST COMPRESSION PLATE COMPRISING AN INFLATABLE ENVELOPE |
| US11707244B2 (en) | 2017-08-16 | 2023-07-25 | Hologic, Inc. | Techniques for breast imaging patient motion artifact compensation |
| EP3449835B1 (en) | 2017-08-22 | 2023-01-11 | Hologic, Inc. | Computed tomography system and method for imaging multiple anatomical targets |
| US11090017B2 (en) | 2018-09-13 | 2021-08-17 | Hologic, Inc. | Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging |
| WO2020068851A1 (en) | 2018-09-24 | 2020-04-02 | Hologic, Inc. | Breast mapping and abnormality localization |
| JP7482860B2 (ja) | 2018-09-28 | 2024-05-14 | ホロジック， インコーポレイテッド | 高密度要素抑制による合成乳房組織画像発生のためのシステムおよび方法 |
| DE202019006040U1 (de) | 2018-11-25 | 2024-08-06 | Hologic Inc. | Multimodalitätsaufhängungsprotokolle |
| EP3948884A1 (en) | 2019-03-29 | 2022-02-09 | Hologic, Inc. | Snip-triggered digital image report generation |
| EP3832689A3 (en) | 2019-12-05 | 2021-08-11 | Hologic, Inc. | Systems and methods for improved x-ray tube life |
| EP4093290A1 (en) | 2020-01-24 | 2022-11-30 | Hologic, Inc. | Horizontally-displaceable foam breast compression paddle |
| US11471118B2 (en) | 2020-03-27 | 2022-10-18 | Hologic, Inc. | System and method for tracking x-ray tube focal spot position |
| CN117255650A (zh) | 2021-04-26 | 2023-12-19 | 豪洛捷公司 | 用于测量泡沫压缩元件的厚度的系统和方法 |
| US11786191B2 (en) | 2021-05-17 | 2023-10-17 | Hologic, Inc. | Contrast-enhanced tomosynthesis with a copper filter |
| US12186119B2 (en) | 2021-10-05 | 2025-01-07 | Hologic, Inc. | Interactive model interface for image selection in medical imaging systems |
| US12254586B2 (en) | 2021-10-25 | 2025-03-18 | Hologic, Inc. | Auto-focus tool for multimodality image review |
| KR20240118765A (ko) | 2021-11-29 | 2024-08-05 | 홀로직, 인크. | 관심 객체들을 상관시키기 위한 시스템들 및 방법들 |
| US12414217B2 (en) | 2022-02-07 | 2025-09-09 | Hologic, Inc. | Systems and methods for adaptively controlling filament current in an X-ray tube |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3609167A (en) * | 1962-04-02 | 1971-09-28 | Smith Kline French Lab | IBENZO{8 b,e{9 {0 THIEPINES |
| NL125253C (OSRAM) * | 1963-12-05 | |||
| NL152845B (nl) * | 1966-03-11 | 1977-04-15 | Boehringer Mannheim Gmbh | Werkwijze voor het bereiden van een geneesmiddel met een psychotrope en bloedsomloopstimulerende werking, alsmede het aldus verkregen gevormde geneesmiddel, en werkwijze voor het bereiden van een geneeskrachtig omega,omega-difenylalkylaminederivaat. |
| FR1518226A (fr) * | 1966-04-09 | 1968-03-22 | Boehringer & Soehne Gmbh | Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide |
| US4463001A (en) * | 1980-10-20 | 1984-07-31 | Farmitalia Carlo Erba S.P.A. | 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation |
-
1981
- 1981-08-27 FR FR8116347A patent/FR2512024A1/fr active Granted
-
1982
- 1982-08-16 US US06/408,451 patent/US4496557A/en not_active Expired - Fee Related
- 1982-08-20 CA CA000409886A patent/CA1227481A/fr not_active Expired
- 1982-08-24 EP EP82401567A patent/EP0074304B1/fr not_active Expired
- 1982-08-24 DE DE8282401567T patent/DE3262880D1/de not_active Expired
- 1982-08-24 AT AT82401567T patent/ATE12497T1/de active
- 1982-08-25 ES ES515232A patent/ES515232A0/es active Granted
- 1982-08-25 GR GR69103A patent/GR77595B/el unknown
- 1982-08-26 AU AU87730/82A patent/AU8773082A/en not_active Abandoned
- 1982-08-26 JP JP57148452A patent/JPS5874673A/ja active Granted
- 1982-08-26 IL IL66650A patent/IL66650A/xx unknown
- 1982-08-26 ZA ZA826252A patent/ZA826252B/xx unknown
- 1982-08-26 PT PT75471A patent/PT75471B/pt unknown
- 1982-08-27 NZ NZ201740A patent/NZ201740A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3262880D1 (en) | 1985-05-09 |
| CA1227481A (fr) | 1987-09-29 |
| JPS5874673A (ja) | 1983-05-06 |
| GR77595B (OSRAM) | 1984-09-25 |
| EP0074304A1 (fr) | 1983-03-16 |
| JPS6129950B2 (OSRAM) | 1986-07-10 |
| EP0074304B1 (fr) | 1985-04-03 |
| ES8400422A1 (es) | 1983-11-01 |
| IL66650A (en) | 1985-08-30 |
| NZ201740A (en) | 1985-05-31 |
| ATE12497T1 (de) | 1985-04-15 |
| AU8773082A (en) | 1983-03-03 |
| FR2512024B1 (OSRAM) | 1984-01-06 |
| PT75471A (fr) | 1982-09-01 |
| IL66650A0 (en) | 1982-12-31 |
| PT75471B (fr) | 1984-11-19 |
| US4496557A (en) | 1985-01-29 |
| FR2512024A1 (fr) | 1983-03-04 |
| ES515232A0 (es) | 1983-11-01 |
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