DE3262880D1 - Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations - Google Patents

Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations

Info

Publication number
DE3262880D1
DE3262880D1 DE8282401567T DE3262880T DE3262880D1 DE 3262880 D1 DE3262880 D1 DE 3262880D1 DE 8282401567 T DE8282401567 T DE 8282401567T DE 3262880 T DE3262880 T DE 3262880T DE 3262880 D1 DE3262880 D1 DE 3262880D1
Authority
DE
Germany
Prior art keywords
group
lower alkyl
preparation
pharmaceutical preparations
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282401567T
Other languages
English (en)
Inventor
Charles Malen
Jean-Claude Poignant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE3262880D1 publication Critical patent/DE3262880D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12[b,e]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/18[b, e]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8282401567T 1981-08-27 1982-08-24 Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations Expired DE3262880D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8116347A FR2512024A1 (fr) 1981-08-27 1981-08-27 Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DE3262880D1 true DE3262880D1 (en) 1985-05-09

Family

ID=9261704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282401567T Expired DE3262880D1 (en) 1981-08-27 1982-08-24 Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations

Country Status (14)

Country Link
US (1) US4496557A (de)
EP (1) EP0074304B1 (de)
JP (1) JPS5874673A (de)
AT (1) ATE12497T1 (de)
AU (1) AU8773082A (de)
CA (1) CA1227481A (de)
DE (1) DE3262880D1 (de)
ES (1) ES515232A0 (de)
FR (1) FR2512024A1 (de)
GR (1) GR77595B (de)
IL (1) IL66650A (de)
NZ (1) NZ201740A (de)
PT (1) PT75471B (de)
ZA (1) ZA826252B (de)

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SE8500273D0 (sv) * 1985-01-22 1985-01-22 Leo Ab Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder
EP0332246A1 (de) * 1988-03-11 1989-09-13 Akzo N.V. Trizyklische Amin-Derivate
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5006536A (en) * 1989-12-26 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Thienobenzoxepins and analgesic compositions thereof
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
US7577282B2 (en) 2002-11-27 2009-08-18 Hologic, Inc. Image handling and display in X-ray mammography and tomosynthesis
US7123684B2 (en) * 2002-11-27 2006-10-17 Hologic, Inc. Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing
US10638994B2 (en) 2002-11-27 2020-05-05 Hologic, Inc. X-ray mammography with tomosynthesis
US8565372B2 (en) 2003-11-26 2013-10-22 Hologic, Inc System and method for low dose tomosynthesis
US8571289B2 (en) 2002-11-27 2013-10-29 Hologic, Inc. System and method for generating a 2D image from a tomosynthesis data set
US7616801B2 (en) 2002-11-27 2009-11-10 Hologic, Inc. Image handling and display in x-ray mammography and tomosynthesis
US8768026B2 (en) * 2003-11-26 2014-07-01 Hologic, Inc. X-ray imaging with x-ray markers that provide adjunct information but preserve image quality
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
EP2602743B1 (de) 2004-11-15 2014-11-05 Hologic, Inc. Erzeugung und Anzeige mit übereinstimmenden Geometrie von Mammogrammen und Tomosynthesebildern
EP1816965B1 (de) 2004-11-26 2016-06-29 Hologic, Inc. Integriertes multimodus-mammographie-/tomosynthese-röntgensystem
US7245694B2 (en) 2005-08-15 2007-07-17 Hologic, Inc. X-ray mammography/tomosynthesis of patient's breast
WO2013078476A1 (en) 2011-11-27 2013-05-30 Hologic, Inc. System and method for generating a 2d image using mammography and/or tomosynthesis image data
US8079946B2 (en) 2005-11-18 2011-12-20 Senorx, Inc. Asymmetrical irradiation of a body cavity
DE202007019497U1 (de) 2006-02-15 2013-03-06 Hologic, Inc. Brustbiopsie und Nadellokalisierung unter Verwendung von Tomosynthesesystemen
US7630533B2 (en) 2007-09-20 2009-12-08 Hologic, Inc. Breast tomosynthesis with display of highlighted suspected calcifications
US7991106B2 (en) * 2008-08-29 2011-08-02 Hologic, Inc. Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles
KR20110063659A (ko) 2008-09-04 2011-06-13 홀로직, 인크. 통합된 다중 모드 마모그래피/토모신테시스 x선 시스템 및 방법
US9248311B2 (en) 2009-02-11 2016-02-02 Hologic, Inc. System and method for modifying a flexibility of a brachythereapy catheter
US9579524B2 (en) 2009-02-11 2017-02-28 Hologic, Inc. Flexible multi-lumen brachytherapy device
US8170320B2 (en) * 2009-03-03 2012-05-01 Hologic, Inc. Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly
US10207126B2 (en) 2009-05-11 2019-02-19 Cytyc Corporation Lumen visualization and identification system for multi-lumen balloon catheter
JP5762423B2 (ja) 2009-10-08 2015-08-12 ホロジック, インコーポレイテッドHologic, Inc. 乳房針生検システム及び使用方法
US9352172B2 (en) 2010-09-30 2016-05-31 Hologic, Inc. Using a guide member to facilitate brachytherapy device swap
EP2624761B1 (de) 2010-10-05 2021-07-14 Hologic, Inc. Bruströntgenbildgebung in aufrechter position mit einem ct-modus, mehreren tomosynthese-modi und einem mammographie-modus
US9075903B2 (en) 2010-11-26 2015-07-07 Hologic, Inc. User interface for medical image review workstation
US10342992B2 (en) 2011-01-06 2019-07-09 Hologic, Inc. Orienting a brachytherapy applicator
US9020579B2 (en) 2011-03-08 2015-04-28 Hologic, Inc. System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy
WO2013123091A1 (en) 2012-02-13 2013-08-22 Hologic, Inc. System and method for navigating a tomosynthesis stack using synthesized image data
JP6388347B2 (ja) 2013-03-15 2018-09-12 ホロジック, インコーポレイテッドHologic, Inc. 腹臥位におけるトモシンセシス誘導生検
CA2925907C (en) 2013-10-09 2022-03-15 Hologic, Inc. X-ray breast tomosynthesis enhancing spatial resolution including in the thickness direction of a flattened breast
EP3110332B1 (de) 2014-02-28 2018-04-11 Hologic Inc. System und verfahren zur erzeugung und anzeige von tomosynthesebildplatten
JP6749322B2 (ja) 2014-11-07 2020-09-02 ホロジック, インコーポレイテッドHologic, Inc. マンモグラフィ/トモシンセシスx線システムのための枢動パドル装置
EP3445247B1 (de) 2016-04-22 2021-03-10 Hologic, Inc. Tomosynthese mit röntgensystem mit variablem brennfleck unter verwendung eines adressierbaren arrays
WO2018089118A1 (en) 2016-11-08 2018-05-17 Hologic, Inc. Imaging with curved compression elements
US11399790B2 (en) 2017-03-30 2022-08-02 Hologic, Inc. System and method for hierarchical multi-level feature image synthesis and representation
JP7174710B2 (ja) 2017-03-30 2022-11-17 ホロジック, インコーポレイテッド 合成乳房組織画像を生成するための標的オブジェクト増強のためのシステムおよび方法
WO2018183549A1 (en) 2017-03-30 2018-10-04 Hologic, Inc. System and method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement
EP3641635A4 (de) 2017-06-20 2021-04-07 Hologic, Inc. Dynamisches selbstlernendes medizinisches bildverfahren und -system
US11064956B2 (en) 2017-08-11 2021-07-20 Hologic, Inc. Breast compression paddle having an inflatable jacket
CN110996801B (zh) 2017-08-11 2023-10-03 豪洛捷公司 具有接近角部的乳房压迫板
EP3668404B1 (de) 2017-08-16 2022-07-06 Hologic, Inc. Verfahren zur kompensation von bewegungsartefakten eines patienten bei der brustbildgebung
EP3449835B1 (de) 2017-08-22 2023-01-11 Hologic, Inc. Computertomografiesystem und methode zur bildgebung mehrerer anatomischer ziele
US11090017B2 (en) 2018-09-13 2021-08-17 Hologic, Inc. Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging
EP3832689A3 (de) 2019-12-05 2021-08-11 Hologic, Inc. Systeme und verfahren für verbesserte röntgenröhrenlebensdauer
WO2021150449A1 (en) 2020-01-24 2021-07-29 Hologic, Inc. Horizontally-displaceable foam breast compression paddle
US11471118B2 (en) 2020-03-27 2022-10-18 Hologic, Inc. System and method for tracking x-ray tube focal spot position
US11786191B2 (en) 2021-05-17 2023-10-17 Hologic, Inc. Contrast-enhanced tomosynthesis with a copper filter

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3609167A (en) * 1962-04-02 1971-09-28 Smith Kline French Lab IBENZO{8 b,e{9 {0 THIEPINES
NL125253C (de) * 1963-12-05
NL152845B (nl) * 1966-03-11 1977-04-15 Boehringer Mannheim Gmbh Werkwijze voor het bereiden van een geneesmiddel met een psychotrope en bloedsomloopstimulerende werking, alsmede het aldus verkregen gevormde geneesmiddel, en werkwijze voor het bereiden van een geneeskrachtig omega,omega-difenylalkylaminederivaat.
FR1518226A (fr) * 1966-04-09 1968-03-22 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide
US4463001A (en) * 1980-10-20 1984-07-31 Farmitalia Carlo Erba S.P.A. 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation

Also Published As

Publication number Publication date
FR2512024A1 (fr) 1983-03-04
EP0074304B1 (de) 1985-04-03
PT75471B (fr) 1984-11-19
IL66650A0 (en) 1982-12-31
ATE12497T1 (de) 1985-04-15
ES8400422A1 (es) 1983-11-01
PT75471A (fr) 1982-09-01
AU8773082A (en) 1983-03-03
ES515232A0 (es) 1983-11-01
ZA826252B (en) 1983-07-27
JPS6129950B2 (de) 1986-07-10
EP0074304A1 (de) 1983-03-16
GR77595B (de) 1984-09-25
US4496557A (en) 1985-01-29
CA1227481A (fr) 1987-09-29
IL66650A (en) 1985-08-30
FR2512024B1 (de) 1984-01-06
NZ201740A (en) 1985-05-31
JPS5874673A (ja) 1983-05-06

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee