ZA82261B - Process for the preparation of human insulin or the derivatives thereof from pig insulin or the derivatives thereof - Google Patents

Process for the preparation of human insulin or the derivatives thereof from pig insulin or the derivatives thereof

Info

Publication number
ZA82261B
ZA82261B ZA82261A ZA82261A ZA82261B ZA 82261 B ZA82261 B ZA 82261B ZA 82261 A ZA82261 A ZA 82261A ZA 82261 A ZA82261 A ZA 82261A ZA 82261 B ZA82261 B ZA 82261B
Authority
ZA
South Africa
Prior art keywords
derivatives
insulin
pig
preparation
human insulin
Prior art date
Application number
ZA82261A
Other languages
English (en)
Inventor
Rainer Obermeier
Juergen Ludwig
Gerhard Seipke
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA82261B publication Critical patent/ZA82261B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA82261A 1981-01-17 1982-01-15 Process for the preparation of human insulin or the derivatives thereof from pig insulin or the derivatives thereof ZA82261B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813101382 DE3101382A1 (de) 1981-01-17 1981-01-17 "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Publications (1)

Publication Number Publication Date
ZA82261B true ZA82261B (en) 1982-12-29

Family

ID=6122819

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA82261A ZA82261B (en) 1981-01-17 1982-01-15 Process for the preparation of human insulin or the derivatives thereof from pig insulin or the derivatives thereof

Country Status (14)

Country Link
US (1) US4601852A (ko)
EP (1) EP0056951B1 (ko)
JP (1) JPS57138396A (ko)
KR (1) KR880001107B1 (ko)
AT (1) ATE13893T1 (ko)
AU (1) AU559235B2 (ko)
CA (1) CA1190496A (ko)
DE (2) DE3101382A1 (ko)
DK (1) DK149615B (ko)
ES (1) ES8301206A1 (ko)
FI (1) FI79860C (ko)
GR (1) GR74758B (ko)
IL (1) IL64789A (ko)
ZA (1) ZA82261B (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
EP0087238A1 (en) * 1982-02-08 1983-08-31 Biogen N.V. Am improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) * 1982-03-13 1983-09-15 Hoechst Ag, 6230 Frankfurt Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
EP0367302A3 (en) * 1982-04-23 1991-06-19 Wako Pure Chemical Industries, Ltd. Process for semi-synthesis of human insulin, water-soluble cross-linked achromobacter protease i for use therein and a process for preparing the same
IT1189353B (it) * 1982-06-07 1988-02-04 Nordisk Insulinlab Procedimento per la preparazione di insulina umana e suoi esteri
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DE3334407A1 (de) * 1983-09-23 1985-04-04 Hoechst Ag, 6230 Frankfurt In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE4028120C2 (de) 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
US5106510A (en) * 1991-03-08 1992-04-21 Enviroguard, Inc. Combined filtration and fixation of heavy metals
DE59208181D1 (de) * 1991-12-18 1997-04-17 Hoechst Ag Verfahren zur Gewinnung von insulinhaltigen Lösungen
DE4404168A1 (de) * 1994-02-10 1995-08-17 Hoechst Ag Hirudinderivate und Verfahren zu deren Herstellung
CA2306905A1 (en) 1997-10-24 1999-05-06 Eli Lilly And Company Fatty acid-acylated insulin analogs
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US6964561B2 (en) * 2002-04-23 2005-11-15 V System Composites, Inc. High-performance infusion system for VARTM fabrication
US20070108646A1 (en) * 2005-11-15 2007-05-17 Louderback Michael J Method of fabricating a composite structure with details

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
DE2460753A1 (de) * 1974-12-21 1976-06-24 Hoechst Ag Verfahren zur herstellung von humaninsulin
DE3064479D1 (en) * 1979-04-13 1983-09-08 Shionogi & Co Process for preparing a b30-threonine insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner

Also Published As

Publication number Publication date
ES508657A0 (es) 1982-11-16
CA1190496A (en) 1985-07-16
GR74758B (ko) 1984-07-11
DK149615B (da) 1986-08-11
AU7955482A (en) 1982-07-29
JPH0141317B2 (ko) 1989-09-05
DE3264149D1 (en) 1985-07-25
DE3101382A1 (de) 1982-09-02
IL64789A0 (en) 1982-03-31
JPS57138396A (en) 1982-08-26
AU559235B2 (en) 1987-03-05
US4601852A (en) 1986-07-22
ATE13893T1 (de) 1985-07-15
FI820117L (fi) 1982-07-18
IL64789A (en) 1985-09-29
FI79860C (fi) 1990-03-12
EP0056951A1 (de) 1982-08-04
KR830008995A (ko) 1983-12-16
ES8301206A1 (es) 1982-11-16
EP0056951B1 (de) 1985-06-19
DK16682A (da) 1982-07-18
KR880001107B1 (ko) 1988-06-29
FI79860B (fi) 1989-11-30

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