ZA803434B - Indolizine derivatives, process for preparing the same andd uses in therapeutics - Google Patents
Indolizine derivatives, process for preparing the same andd uses in therapeuticsInfo
- Publication number
- ZA803434B ZA803434B ZA00803434A ZA803434A ZA803434B ZA 803434 B ZA803434 B ZA 803434B ZA 00803434 A ZA00803434 A ZA 00803434A ZA 803434 A ZA803434 A ZA 803434A ZA 803434 B ZA803434 B ZA 803434B
- Authority
- ZA
- South Africa
- Prior art keywords
- andd
- therapeutics
- preparing
- same
- indolizine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7923599 | 1979-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA803434B true ZA803434B (en) | 1981-05-27 |
Family
ID=10506339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00803434A ZA803434B (en) | 1979-07-06 | 1980-06-09 | Indolizine derivatives, process for preparing the same andd uses in therapeutics |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4400387A (pt) |
| EP (1) | EP0022762B1 (pt) |
| JP (1) | JPS5618979A (pt) |
| AR (1) | AR225314A1 (pt) |
| AT (1) | AT375078B (pt) |
| AU (1) | AU529725B2 (pt) |
| CA (1) | CA1153379A (pt) |
| DD (1) | DD151940A5 (pt) |
| DE (1) | DE3060097D1 (pt) |
| DK (1) | DK146962C (pt) |
| ES (1) | ES8105710A1 (pt) |
| FI (1) | FI67217C (pt) |
| GR (1) | GR69280B (pt) |
| HU (1) | HU182151B (pt) |
| IE (1) | IE49994B1 (pt) |
| IN (1) | IN151594B (pt) |
| NO (1) | NO153496C (pt) |
| NZ (1) | NZ193926A (pt) |
| OA (1) | OA06563A (pt) |
| PL (1) | PL125597B1 (pt) |
| PT (1) | PT71424A (pt) |
| SU (1) | SU993817A3 (pt) |
| YU (1) | YU171880A (pt) |
| ZA (1) | ZA803434B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6103702A (en) * | 1999-05-24 | 2000-08-15 | Board Of Trustees Of The University Of Illinois | Use of adenosine deaminase inhibitors to treat systemic inflammatory response syndrome |
| EP1200102A1 (en) * | 1999-07-22 | 2002-05-02 | Supergen, Inc. | Methods for treating autoimmune diseases |
| FR2805460A1 (fr) | 2000-02-25 | 2001-08-31 | Oreal | Compositions de teinture des fibres keratiniques contenant des derives d'indolizine cationiques et procede de teinture |
| FR2838123B1 (fr) * | 2002-04-04 | 2005-06-10 | Sanofi Synthelabo | Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf |
| JP4048166B2 (ja) * | 2002-11-18 | 2008-02-13 | 三井製糖株式会社 | 血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料 |
| FR2859997B1 (fr) * | 2003-09-18 | 2006-02-03 | Sanofi Synthelabo | Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| FR2896247B1 (fr) | 2006-01-13 | 2008-02-29 | Sanofi Aventis Sa | Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique |
| SI2415771T1 (sl) * | 2009-03-31 | 2013-12-31 | Kissei Pharmaceutical Co., Ltd. | Derivat indolizina in njegova uporaba v medicinske namene |
| US20100261666A1 (en) * | 2009-04-14 | 2010-10-14 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis |
| EP2623505B1 (en) * | 2010-09-29 | 2015-07-29 | Kissei Pharmaceutical Co., Ltd. | (aza)indolizine derivatives as xanthine oxidase inhibitors |
| CA2998034C (en) * | 2015-09-10 | 2021-05-04 | Dongfang Shi | A group of compounds used for the treatment or prevention of hyperuricemia or gout |
| WO2018090921A1 (zh) | 2016-11-16 | 2018-05-24 | 江苏新元素医药科技有限公司 | Urat1抑制剂及其应用 |
| CN108084186B (zh) | 2016-11-16 | 2021-06-25 | 江苏新元素医药科技有限公司 | Urat1抑制剂及其应用 |
| CN108484600B (zh) * | 2017-05-26 | 2022-12-13 | 江苏新元素医药科技有限公司 | 促尿酸排泄的urat1抑制剂 |
| CN114213331B (zh) * | 2017-05-26 | 2024-06-21 | 江苏新元素医药科技有限公司 | 一类urat1抑制剂及其应用 |
| US11453674B2 (en) | 2018-01-19 | 2022-09-27 | Evopoint Biosciences Co., Ltd. | Heterocyclic compound, preparation method and use thereof in medicine |
| CN110283167A (zh) * | 2018-11-14 | 2019-09-27 | 贵州省中国科学院天然产物化学重点实验室 | 一种抗心率失常药物布托普洛嗪的制备方法 |
| WO2022169974A1 (en) | 2021-02-05 | 2022-08-11 | Nexys Therapeutics, Inc. | Inhibitors of urat1 and pharmaceutical uses thereof |
| WO2023221078A1 (en) * | 2022-05-20 | 2023-11-23 | Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. | Solid forms of a compound for treating or preventing hyperuricemia or gout |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU430639A1 (ru) | 1972-06-05 | 1978-02-28 | Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова | Способ получени 1-пиридилиндолизинов |
| GB1518443A (en) * | 1976-02-19 | 1978-07-19 | Labaz | Indolizine derivatives and process for preparing the same |
| FI61030C (fi) | 1976-02-19 | 1982-05-10 | Sanofi Sa | Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat |
-
1980
- 1980-06-04 NZ NZ193926A patent/NZ193926A/en unknown
- 1980-06-09 ZA ZA00803434A patent/ZA803434B/xx unknown
- 1980-06-10 GR GR62170A patent/GR69280B/el unknown
- 1980-06-20 PT PT71424A patent/PT71424A/pt unknown
- 1980-06-20 AU AU59487/80A patent/AU529725B2/en not_active Ceased
- 1980-06-26 IN IN738/CAL/80A patent/IN151594B/en unknown
- 1980-06-30 US US06/164,838 patent/US4400387A/en not_active Expired - Lifetime
- 1980-06-30 IE IE1349/80A patent/IE49994B1/en unknown
- 1980-06-30 EP EP80870035A patent/EP0022762B1/fr not_active Expired
- 1980-06-30 DE DE8080870035T patent/DE3060097D1/de not_active Expired
- 1980-07-01 YU YU01718/80A patent/YU171880A/xx unknown
- 1980-07-02 OA OA57151A patent/OA06563A/xx unknown
- 1980-07-02 AR AR281618A patent/AR225314A1/es active
- 1980-07-03 SU SU802942500A patent/SU993817A3/ru active
- 1980-07-04 CA CA000355421A patent/CA1153379A/en not_active Expired
- 1980-07-04 HU HU801674A patent/HU182151B/hu not_active IP Right Cessation
- 1980-07-04 PL PL1980225479A patent/PL125597B1/pl unknown
- 1980-07-04 ES ES493139A patent/ES8105710A1/es not_active Expired
- 1980-07-04 NO NO802015A patent/NO153496C/no unknown
- 1980-07-04 DK DK291180A patent/DK146962C/da not_active IP Right Cessation
- 1980-07-04 DD DD80222415A patent/DD151940A5/de unknown
- 1980-07-04 JP JP9216080A patent/JPS5618979A/ja active Pending
- 1980-07-07 AT AT0354380A patent/AT375078B/de not_active IP Right Cessation
- 1980-07-07 FI FI802165A patent/FI67217C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL125597B1 (en) | 1983-05-31 |
| SU993817A3 (ru) | 1983-01-30 |
| GR69280B (pt) | 1982-05-13 |
| OA06563A (fr) | 1981-07-31 |
| NZ193926A (en) | 1984-05-31 |
| DD151940A5 (de) | 1981-11-11 |
| EP0022762A1 (fr) | 1981-01-21 |
| NO153496C (no) | 1986-05-14 |
| AU529725B2 (en) | 1983-06-16 |
| ES493139A0 (es) | 1981-06-16 |
| DE3060097D1 (en) | 1982-01-28 |
| JPS5618979A (en) | 1981-02-23 |
| IE49994B1 (en) | 1986-01-22 |
| DK146962B (da) | 1984-02-27 |
| AR225314A1 (es) | 1982-03-15 |
| HU182151B (en) | 1983-12-28 |
| PT71424A (en) | 1980-07-01 |
| NO802015L (no) | 1981-01-07 |
| EP0022762B1 (fr) | 1981-11-25 |
| AU5948780A (en) | 1981-01-15 |
| FI67217B (fi) | 1984-10-31 |
| DK146962C (da) | 1984-08-06 |
| CA1153379A (en) | 1983-09-06 |
| ES8105710A1 (es) | 1981-06-16 |
| AT375078B (de) | 1984-06-25 |
| FI67217C (fi) | 1985-02-11 |
| DK291180A (da) | 1981-01-07 |
| IN151594B (pt) | 1983-06-04 |
| US4400387A (en) | 1983-08-23 |
| FI802165A (fi) | 1981-01-07 |
| PL225479A1 (pt) | 1981-10-30 |
| NO153496B (no) | 1985-12-23 |
| YU171880A (en) | 1983-10-31 |
| ATA354380A (de) | 1983-11-15 |
| IE801349L (en) | 1981-01-06 |
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