ZA785354B - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
ZA785354B
ZA785354B ZA00785354A ZA785354A ZA785354B ZA 785354 B ZA785354 B ZA 785354B ZA 00785354 A ZA00785354 A ZA 00785354A ZA 785354 A ZA785354 A ZA 785354A ZA 785354 B ZA785354 B ZA 785354B
Authority
ZA
South Africa
Prior art keywords
therapeutic agents
therapeutic
agents
Prior art date
Application number
ZA00785354A
Other languages
English (en)
Inventor
R Partyka
P Juby
T Hudyma
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ZA785354B publication Critical patent/ZA785354B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16Isothiocyanates
    • C07C331/18Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms
    • C07C331/22Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C331/24Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00785354A 1977-09-21 1978-09-20 Therapeutic agents ZA785354B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/835,266 US4127720A (en) 1977-09-21 1977-09-21 Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity

Publications (1)

Publication Number Publication Date
ZA785354B true ZA785354B (en) 1979-09-26

Family

ID=25269074

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00785354A ZA785354B (en) 1977-09-21 1978-09-20 Therapeutic agents

Country Status (18)

Country Link
US (1) US4127720A (de)
JP (1) JPS5463099A (de)
AU (1) AU522646B2 (de)
BE (1) BE870634A (de)
CA (1) CA1108613A (de)
CH (1) CH642967A5 (de)
DE (1) DE2841126A1 (de)
DK (1) DK164553C (de)
FI (1) FI65246C (de)
FR (1) FR2404010A1 (de)
GB (1) GB2004876B (de)
GR (1) GR72144B (de)
IE (1) IE47189B1 (de)
LU (1) LU80272A1 (de)
NL (1) NL190071C (de)
SE (1) SE438335B (de)
YU (2) YU41598B (de)
ZA (1) ZA785354B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
US4472401A (en) * 1981-11-27 1984-09-18 Roussel Uclaf Pyrimido-quinoxalines having antiallergic properties
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
GB8331228D0 (en) * 1983-11-23 1983-12-29 Fujisawa Pharmaceutical Co Pyrimidoisoquinoline derivatives
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives
CA2251681A1 (en) * 1996-04-13 1997-10-23 Peter Hamley Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents
CN101084227B (zh) * 2004-12-20 2011-11-16 惠氏公司 雷帕霉素类似物及其治疗神经紊乱、增殖性和炎性疾病的用途
CN101084226A (zh) 2004-12-20 2007-12-05 惠氏公司 雷帕霉素衍生物及其治疗神经紊乱的用途
EP4320117A2 (de) * 2021-04-04 2024-02-14 Baruch S. Blumberg Institute Neue hepatoselektive polyadenylierende polymerasen-hemmer und verfahren zu ihrer verwendung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356937A (en) * 1970-08-27 1974-06-19 Wellcome Found Pyrimido-isoquinolines
BE792648A (fr) * 1971-12-13 1973-06-12 May & Baker Ltd Derives de l'isoquinoleine
CA1033731A (en) * 1974-04-01 1978-06-27 Saul B. Kadin Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
SU685156A3 (ru) * 1975-08-01 1979-09-05 Пфайзер Инк (Фирма) Способ получени -(5-тетразолил(1-оксо-1н-пиримидо-)1,2-а) хинолин-2-карбоксамида
US4017625A (en) * 1975-08-01 1977-04-12 Pfizer Inc. Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
FI65246B (fi) 1983-12-30
GB2004876B (en) 1982-03-10
YU44501B (en) 1990-08-31
CH642967A5 (de) 1984-05-15
DK413578A (da) 1979-03-22
FR2404010B1 (de) 1980-10-31
FI782849A (fi) 1979-03-22
NL190071B (nl) 1993-05-17
NL7809626A (nl) 1979-03-23
DE2841126A1 (de) 1979-04-05
JPS5463099A (en) 1979-05-21
SE438335B (sv) 1985-04-15
DK164553B (da) 1992-07-13
DK164553C (da) 1992-11-30
DE2841126C2 (de) 1990-05-17
YU222778A (en) 1984-02-29
BE870634A (fr) 1979-03-20
FR2404010A1 (fr) 1979-04-20
CA1108613A (en) 1981-09-08
FI65246C (fi) 1984-04-10
GB2004876A (en) 1979-04-11
AU522646B2 (en) 1982-06-17
NL190071C (nl) 1993-10-18
YU41598B (en) 1987-10-31
YU63585A (en) 1986-04-30
GR72144B (de) 1983-09-20
US4127720A (en) 1978-11-28
AU4004278A (en) 1980-03-27
SE7809887L (sv) 1979-03-22
LU80272A1 (fr) 1979-06-01
IE781897L (en) 1979-03-21
IE47189B1 (en) 1984-01-11
JPS6212225B2 (de) 1987-03-17

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