FI782849A - Terapeutiska medel - Google Patents

Terapeutiska medel

Info

Publication number
FI782849A
FI782849A FI782849A FI782849A FI782849A FI 782849 A FI782849 A FI 782849A FI 782849 A FI782849 A FI 782849A FI 782849 A FI782849 A FI 782849A FI 782849 A FI782849 A FI 782849A
Authority
FI
Finland
Prior art keywords
medel
therapeutic
therapeutic medel
Prior art date
Application number
FI782849A
Other languages
English (en)
Other versions
FI65246B (fi
FI65246C (fi
Inventor
Peter Frederick Juby
Thomas William Hudyma
Richard Anthony Partyka
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI782849A publication Critical patent/FI782849A/fi
Priority to FI824509A priority Critical patent/FI68051C/fi
Publication of FI65246B publication Critical patent/FI65246B/fi
Application granted granted Critical
Publication of FI65246C publication Critical patent/FI65246C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16Isothiocyanates
    • C07C331/18Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms
    • C07C331/22Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C331/24Isothiocyanates having isothiocyanate groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI782849A 1977-09-21 1978-09-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrimido(2,1-a)isokinolin-3-karboxylsyraderivat FI65246C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI824509A FI68051C (fi) 1977-09-21 1982-12-29 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-(1h-tetrazol-5-yl)-4h-pyrimido(2,1-a)isokinolin-4-oner samt farmaceutiskt godtagbara salter av dessa foereningar

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83526677 1977-09-21
US05/835,266 US4127720A (en) 1977-09-21 1977-09-21 Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity

Publications (3)

Publication Number Publication Date
FI782849A true FI782849A (fi) 1979-03-22
FI65246B FI65246B (fi) 1983-12-30
FI65246C FI65246C (fi) 1984-04-10

Family

ID=25269074

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782849A FI65246C (fi) 1977-09-21 1978-09-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrimido(2,1-a)isokinolin-3-karboxylsyraderivat

Country Status (18)

Country Link
US (1) US4127720A (fi)
JP (1) JPS5463099A (fi)
AU (1) AU522646B2 (fi)
BE (1) BE870634A (fi)
CA (1) CA1108613A (fi)
CH (1) CH642967A5 (fi)
DE (1) DE2841126A1 (fi)
DK (1) DK164553C (fi)
FI (1) FI65246C (fi)
FR (1) FR2404010A1 (fi)
GB (1) GB2004876B (fi)
GR (1) GR72144B (fi)
IE (1) IE47189B1 (fi)
LU (1) LU80272A1 (fi)
NL (1) NL190071C (fi)
SE (1) SE438335B (fi)
YU (2) YU41598B (fi)
ZA (1) ZA785354B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
US4472401A (en) * 1981-11-27 1984-09-18 Roussel Uclaf Pyrimido-quinoxalines having antiallergic properties
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
GB8331228D0 (en) * 1983-11-23 1983-12-29 Fujisawa Pharmaceutical Co Pyrimidoisoquinoline derivatives
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives
BR9708607A (pt) * 1996-04-13 1999-08-03 Astra Pharma Prod Composto composição farmacéutica utilização de um composto processo para tratamento ou redução do risco de doença inflamatória num paciente e para a preparação de um composto e intermediário químico
WO2006068905A2 (en) * 2004-12-20 2006-06-29 Wyeth Rapamycin derivatives and the uses thereof in the treatment of neurological disorders
AU2005319454B2 (en) * 2004-12-20 2012-08-09 Wyeth Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders
WO2022216552A2 (en) * 2021-04-04 2022-10-13 Baruch S. Blumberg Institute Novel hepatoselective polyadenylating polymerases inhibitors and their method of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356937A (en) * 1970-08-27 1974-06-19 Wellcome Found Pyrimido-isoquinolines
BE792648A (fr) * 1971-12-13 1973-06-12 May & Baker Ltd Derives de l'isoquinoleine
CA1033731A (en) * 1974-04-01 1978-06-27 Saul B. Kadin Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
SU685156A3 (ru) * 1975-08-01 1979-09-05 Пфайзер Инк (Фирма) Способ получени -(5-тетразолил(1-оксо-1н-пиримидо-)1,2-а) хинолин-2-карбоксамида
US4017625A (en) * 1975-08-01 1977-04-12 Pfizer Inc. Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
AU522646B2 (en) 1982-06-17
FI65246B (fi) 1983-12-30
YU44501B (en) 1990-08-31
SE7809887L (sv) 1979-03-22
GR72144B (fi) 1983-09-20
FR2404010A1 (fr) 1979-04-20
YU222778A (en) 1984-02-29
NL7809626A (nl) 1979-03-23
BE870634A (fr) 1979-03-20
YU63585A (en) 1986-04-30
FR2404010B1 (fi) 1980-10-31
NL190071C (nl) 1993-10-18
DK164553C (da) 1992-11-30
DE2841126C2 (fi) 1990-05-17
JPS6212225B2 (fi) 1987-03-17
GB2004876B (en) 1982-03-10
NL190071B (nl) 1993-05-17
DK413578A (da) 1979-03-22
CH642967A5 (de) 1984-05-15
DE2841126A1 (de) 1979-04-05
US4127720A (en) 1978-11-28
IE781897L (en) 1979-03-21
ZA785354B (en) 1979-09-26
AU4004278A (en) 1980-03-27
IE47189B1 (en) 1984-01-11
GB2004876A (en) 1979-04-11
CA1108613A (en) 1981-09-08
YU41598B (en) 1987-10-31
DK164553B (da) 1992-07-13
JPS5463099A (en) 1979-05-21
SE438335B (sv) 1985-04-15
FI65246C (fi) 1984-04-10
LU80272A1 (fr) 1979-06-01

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS CO