ZA785335B - Xanthine derivatives - Google Patents
Xanthine derivativesInfo
- Publication number
- ZA785335B ZA785335B ZA00785335A ZA785335A ZA785335B ZA 785335 B ZA785335 B ZA 785335B ZA 00785335 A ZA00785335 A ZA 00785335A ZA 785335 A ZA785335 A ZA 785335A ZA 785335 B ZA785335 B ZA 785335B
- Authority
- ZA
- South Africa
- Prior art keywords
- xanthine derivatives
- xanthine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7711581A SE416810C (sv) | 1977-10-14 | 1977-10-14 | Forfarande for framstellning av xantinderivat med antiallergisk aktivitet |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA785335B true ZA785335B (en) | 1979-09-26 |
Family
ID=20332576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA00785335A ZA785335B (en) | 1977-10-14 | 1978-09-19 | Xanthine derivatives |
Country Status (21)
Country | Link |
---|---|
US (1) | US4233303A (sv) |
EP (1) | EP0001735B1 (sv) |
JP (1) | JPS5479296A (sv) |
AT (1) | AT363491B (sv) |
AU (1) | AU521585B2 (sv) |
CA (1) | CA1109470A (sv) |
CS (1) | CS208756B2 (sv) |
DD (1) | DD139855A5 (sv) |
DE (1) | DE2862017D1 (sv) |
DK (1) | DK148260C (sv) |
FI (1) | FI66383C (sv) |
HK (1) | HK6385A (sv) |
HU (1) | HU180219B (sv) |
IE (1) | IE47884B1 (sv) |
IT (1) | IT1109208B (sv) |
NO (1) | NO147562C (sv) |
NZ (1) | NZ188566A (sv) |
SE (1) | SE416810C (sv) |
SG (1) | SG85584G (sv) |
SU (1) | SU755199A3 (sv) |
ZA (1) | ZA785335B (sv) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7810947L (sv) * | 1978-10-20 | 1980-04-21 | Draco Ab | 3-alkylxanthines |
SE8002910L (sv) * | 1980-04-18 | 1981-10-19 | Draco Ab | 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar |
US4755517A (en) * | 1986-07-31 | 1988-07-05 | Warner-Lambert Company | Derivatives of xanthine, pharmaceutical compositions and methods of use therefor |
US5298508A (en) * | 1988-07-19 | 1994-03-29 | The United States Of America As Represented By The Department Of Health And Human Services | Irreversible inhibitors of adenosine receptors |
US5321029A (en) * | 1988-11-14 | 1994-06-14 | Beecham-Wuelfing Gmbh & Co.K.G. | Xanthines |
GB8826595D0 (en) * | 1988-11-14 | 1988-12-21 | Beecham Wuelfing Gmbh & Co Kg | Active compounds |
IT1229195B (it) * | 1989-03-10 | 1991-07-25 | Poli Ind Chimica Spa | Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche. |
GB8929208D0 (en) * | 1989-12-27 | 1990-02-28 | Almirall Lab | New xanthine derivatives |
US5047534A (en) * | 1990-03-26 | 1991-09-10 | Merrell Dow Pharmaceuticals Inc. | Selective adenosine receptor agents |
US5342841A (en) * | 1992-03-12 | 1994-08-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
US5366977A (en) * | 1992-09-29 | 1994-11-22 | The United States Of America, As Represented By The Department Of Health And Human Services | Method of treating cystic fibrosis using 8-cyclopentyl-1,3-dipropylxanthine or xanthine amino congeners |
US5395836A (en) * | 1993-04-07 | 1995-03-07 | Kyowa Hakko Kogyo Co., Ltd. | 8-tricycloalkyl xanthine derivatives |
GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
US5661153A (en) * | 1994-07-19 | 1997-08-26 | Japan Energy Corporation | 1-arylpyrimidine derivatives and pharmaceutical use thereof |
JP2001523213A (ja) * | 1994-12-13 | 2001-11-20 | ユーロ−セルティーク,エス.エイ. | 三置換チオキサンチン類 |
US6066641A (en) * | 1994-12-13 | 2000-05-23 | Euro-Celtique S.A. | Aryl thioxanthines |
US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
US5864037A (en) * | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
NZ543109A (en) | 2003-04-25 | 2008-06-30 | Novacardia Inc | Method of improved diuresis in individuals with impaired renal function |
BRPI0509753A (pt) * | 2004-04-16 | 2007-10-16 | Novacardia Inc | composição farmacêutica e método de tratamento de doença cardiovascular |
US20070049757A1 (en) * | 2005-08-26 | 2007-03-01 | Rieger Jayson M | Methods for the synthesis of substituted amino uracils |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
US3900474A (en) * | 1973-05-14 | 1975-08-19 | Kendall & Co | Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines |
US4061753A (en) * | 1976-02-06 | 1977-12-06 | Interx Research Corporation | Treating psoriasis with transient pro-drug forms of xanthine derivatives |
CA1077932A (en) | 1976-03-31 | 1980-05-20 | Berlex Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
US4120947A (en) * | 1976-03-31 | 1978-10-17 | Cooper Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
-
1977
- 1977-10-14 SE SE7711581A patent/SE416810C/sv unknown
-
1978
- 1978-09-19 ZA ZA00785335A patent/ZA785335B/xx unknown
- 1978-09-29 US US05/947,002 patent/US4233303A/en not_active Expired - Lifetime
- 1978-10-03 NZ NZ188566A patent/NZ188566A/en unknown
- 1978-10-03 AU AU40365/78A patent/AU521585B2/en not_active Expired
- 1978-10-03 DE DE7878850015T patent/DE2862017D1/de not_active Expired
- 1978-10-03 EP EP78850015A patent/EP0001735B1/en not_active Expired
- 1978-10-04 AT AT0714478A patent/AT363491B/de not_active IP Right Cessation
- 1978-10-10 CA CA313,026A patent/CA1109470A/en not_active Expired
- 1978-10-12 DD DD78208423A patent/DD139855A5/de unknown
- 1978-10-12 DK DK453778A patent/DK148260C/da not_active IP Right Cessation
- 1978-10-13 NO NO783471A patent/NO147562C/no unknown
- 1978-10-13 HU HU78DA359A patent/HU180219B/hu unknown
- 1978-10-13 FI FI783126A patent/FI66383C/fi not_active IP Right Cessation
- 1978-10-13 IT IT51499/78A patent/IT1109208B/it active
- 1978-10-13 IE IE2041/78A patent/IE47884B1/en unknown
- 1978-10-13 CS CS786669A patent/CS208756B2/cs unknown
- 1978-10-13 SU SU782675299A patent/SU755199A3/ru active
- 1978-10-14 JP JP12573978A patent/JPS5479296A/ja active Pending
-
1984
- 1984-11-29 SG SG855/84A patent/SG85584G/en unknown
-
1985
- 1985-01-24 HK HK63/85A patent/HK6385A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DD139855A5 (de) | 1980-01-23 |
CS208756B2 (en) | 1981-09-15 |
SE7711581L (sv) | 1979-04-15 |
NZ188566A (en) | 1984-07-06 |
DK148260C (da) | 1986-02-10 |
HU180219B (en) | 1983-02-28 |
HK6385A (en) | 1985-02-01 |
FI66383B (fi) | 1984-06-29 |
IE47884B1 (en) | 1984-07-11 |
DK148260B (da) | 1985-05-20 |
AU4036578A (en) | 1980-04-17 |
FI66383C (fi) | 1984-10-10 |
FI783126A (fi) | 1979-04-15 |
DE2862017D1 (en) | 1982-10-28 |
EP0001735A1 (en) | 1979-05-02 |
IT1109208B (it) | 1985-12-16 |
SU755199A3 (en) | 1980-08-07 |
NO147562C (no) | 1983-05-18 |
SE416810B (sv) | 1981-02-09 |
EP0001735B1 (en) | 1982-09-01 |
SE416810C (sv) | 1982-07-19 |
CA1109470A (en) | 1981-09-22 |
IE782041L (en) | 1979-04-14 |
US4233303A (en) | 1980-11-11 |
ATA714478A (de) | 1980-09-15 |
NO147562B (no) | 1983-01-24 |
JPS5479296A (en) | 1979-06-25 |
SG85584G (en) | 1985-06-07 |
DK453778A (da) | 1979-04-15 |
IT7851499A0 (it) | 1978-10-13 |
AU521585B2 (en) | 1982-04-22 |
AT363491B (de) | 1981-08-10 |
NO783471L (no) | 1979-04-18 |
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