| US4126680A
              (en)
            
            * | 1977-04-27 | 1978-11-21 | Pfizer Inc. | Tetracycline antibiotic compositions | 
        
          | DE2963584D1
              (en)
            
            * | 1978-08-01 | 1982-10-21 | Ciba Geigy Ag | Stable, liquid pharmaceutical formulation, its preparation and use | 
        
          | DE2965917D1
              (en)
            
            * | 1978-12-08 | 1983-08-25 | Beecham Group Plc | A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof | 
        
          | US4259331A
              (en)
            
            * | 1979-04-16 | 1981-03-31 | Pfizer Inc. | Oxytetracycline compositions | 
        
          | ATE4166T1
              (de)
            
            * | 1979-07-02 | 1983-08-15 | Pfizer Inc. | Langwirkende injizierbare sulfonamidzusammensetzungen. | 
        
          | US4303643A
              (en)
            
            * | 1979-07-05 | 1981-12-01 | Pfizer Inc. | Sulfonamide compositions | 
        
          | DE3063763D1
              (en)
            
            * | 1979-07-05 | 1983-07-21 | Pfizer | Sulfonamide solutions | 
        
          | US4399127A
              (en)
            
            * | 1980-04-10 | 1983-08-16 | Diamond Shamrock Corporation | Injectable oxytetracycline compositions | 
        
          | CA1163197A
              (en)
            
            * | 1980-04-10 | 1984-03-06 | Herman Horn | Injectable oxytetracycline compositions | 
        
          | US4386083A
              (en)
            
            * | 1980-04-10 | 1983-05-31 | Walter Hacke | Injectable oxytetracycline compositions | 
        
          | US4374826A
              (en)
            
            * | 1980-07-21 | 1983-02-22 | Pfizer Inc. | Sulfonamide compositions | 
        
          | NL178941C
              (nl)
            
            * | 1982-06-15 | 1986-06-16 | Aesculaap Bv | Werkwijze voor de bereiding van een waterig oxytetracyclinepreparaat. | 
        
          | US4769232A
              (en)
            
            * | 1984-03-22 | 1988-09-06 | Pfizer Inc. | Parenteral formulations of indolmycin | 
        
          | IE74244B1
              (en)
            
            * | 1985-10-01 | 1997-07-16 | Bimeda Res Dev Ltd | A process for preparing an antibiotic composition | 
        
          | HU194493B
              (en)
            
            * | 1985-11-27 | 1988-02-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing primycin-containing colloidal basic gel and compositions comprising the same | 
        
          | FR2608044B1
              (fr)
            
            * | 1986-12-10 | 1992-09-11 | Sogeval | Composition antibiotique aqueuse a usage veterinaire | 
        
          | US4906475A
              (en)
            
            * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system | 
        
          | US6756365B2
              (en)
            
            * | 1991-11-06 | 2004-06-29 | Trustees Of Tufts College | Reducing tetracycline resistance in living cells | 
        
          | EP0626171A1
              (de)
            
            * | 1993-05-26 | 1994-11-30 | Winfried Dörnhöfer | Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere | 
        
          | ES2130069B1
              (es)
            
            * | 1997-04-10 | 2000-03-01 | Basf Labiana S A | Preparacion farmaceutica con liberacion retardada del producto activo. | 
        
          | US20020077276A1
              (en)
            
            * | 1999-04-27 | 2002-06-20 | Fredeking Terry M. | Compositions and methods for treating hemorrhagic virus infections and other disorders | 
        
          | US6849615B2
              (en) | 1999-09-14 | 2005-02-01 | Paratek Pharmaceuticals, Inc. | 13-substituted methacycline compounds | 
        
          | US8106225B2
              (en)
            
            * | 1999-09-14 | 2012-01-31 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries | 
        
          | EP1666453A1
              (en) | 1999-09-14 | 2006-06-07 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries | 
        
          | US6500812B2
              (en) | 1999-09-14 | 2002-12-31 | Paratek Pharmaceuticals, Inc. | 13-substituted methacycline compounds | 
        
          | AU2001228454A1
              (en)
            
            * | 2000-01-13 | 2001-07-24 | Merck Patent G.M.B.H | Pharmaceutical preparations containing 2-pyrrolidone as the dissolving intermediary | 
        
          | EP1263442A1
              (en) | 2000-01-24 | 2002-12-11 | Trustees Of Tufts College | TETRACYCLINE COMPOUNDS FOR TREATMENT OF  i CRYPTOSPORIDIUM PARVUM /i  RELATED DISORDERS | 
        
          | WO2001074761A1
              (en) | 2000-03-31 | 2001-10-11 | Trustees Of Tufts College | 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds | 
        
          | CA2409063A1
              (en)
            
            * | 2000-05-15 | 2001-11-22 | Mark L. Nelson | 7-substituted fused ring tetracycline compounds | 
        
          | US20020132798A1
              (en)
            
            * | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds | 
        
          | US20040224927A1
              (en)
            
            * | 2000-06-16 | 2004-11-11 | Trustees Of Tufts College | 7-N-substituted phenyl tetracycline compounds | 
        
          | US20020128238A1
              (en)
            
            * | 2000-06-16 | 2002-09-12 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds | 
        
          | US20050143353A1
              (en)
            
            * | 2000-07-07 | 2005-06-30 | Paratek Pharmaceuticals, Inc. | 13-Substituted methacycline compounds | 
        
          | CA2415086A1
              (en) | 2000-07-07 | 2002-01-17 | Trustees Of Tufts College | 7,8 and 9-substituted tetracycline compounds | 
        
          | US7094806B2
              (en)
            
            * | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds | 
        
          | EP2204361B1
              (en) | 2000-07-07 | 2011-09-28 | Trustees Of Tufts College | 13-substituted methacycline compounds | 
        
          | CN1450989A
              (zh)
            
            * | 2000-07-07 | 2003-10-22 | 塔夫茨大学信托人 | 7-取代的四环素化合物 | 
        
          | DK1679305T3
              (da) | 2000-07-07 | 2012-05-29 | Tufts College | 9-substituerede minocyclinforbindelser | 
        
          | RU2178698C1
              (ru)
            
            * | 2000-11-28 | 2002-01-27 | Закрытое Акционерное Общество "Нита-Фарм" | Способ получения композиции магниевого комплекса окситетрациклина пролонгированного действия | 
        
          | EP1241160A1
              (en)
            
            * | 2001-03-13 | 2002-09-18 | Glaxo Group Limited | Tetracycline derivatives and their use as antibiotic agents | 
        
          | US7553828B2
              (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds | 
        
          | ATE404528T1
              (de) | 2001-03-13 | 2008-08-15 | Paratek Pharm Innc | 7,9 substituierte tetracyclinverbindungen | 
        
          | AU2002250331A1
              (en)
            
            * | 2001-03-13 | 2002-09-24 | Paratek Pharmaceuticals, Inc. | 7-pyrollyl tetracycline compounds and methods of use thereof | 
        
          | US7045507B2
              (en) | 2001-03-14 | 2006-05-16 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds as synergistic antifungal agents | 
        
          | JP2004530661A
              (ja)
            
            * | 2001-03-14 | 2004-10-07 | パラテック  ファーマシューティカルズ  インコーポレイテッド | 抗真菌剤としての置換テトラサイクリン化合物 | 
        
          | DE60235083D1
              (de) | 2001-04-24 | 2010-03-04 | Paratek Pharm Innc | Substituierte tetracyclin-verbindungen zur behandlung von malaria | 
        
          | US8088820B2
              (en)
            
            * | 2001-04-24 | 2012-01-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for the treatment of malaria | 
        
          | US20030181371A1
              (en)
            
            * | 2001-12-28 | 2003-09-25 | Angiotech Pharmaceuticals, Inc. | Compositions and methods of using collajolie | 
        
          | WO2003057169A2
              (en) | 2002-01-08 | 2003-07-17 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds | 
        
          | CN101307017A
              (zh) | 2002-03-08 | 2008-11-19 | 帕拉特克药品公司 | 氨基-甲基取代的四环素类化合物 | 
        
          | JP2005520846A
              (ja) | 2002-03-21 | 2005-07-14 | パラテック  ファーマシューティカルズ  インコーポレイテッド | 置換されたテトラサイクリン化合物。 | 
        
          | US6958161B2
              (en) | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation | 
        
          | KR101089429B1
              (ko) | 2002-07-12 | 2011-12-07 | 파라테크 파마슈티컬스, 인크. | 3, 10, 및 12a 치환된 테트라시클린 화합물 | 
        
          | CA2502464A1
              (en) | 2002-10-24 | 2004-05-06 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for the treatment of malaria | 
        
          | KR20050086949A
              (ko)
            
            * | 2002-12-27 | 2005-08-30 | 안지오테크 인터내셔날 아게 | 콜라졸리를 사용한 조성물 및 방법 | 
        
          | US20060287283A1
              (en)
            
            * | 2003-07-09 | 2006-12-21 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds | 
        
          | EP2298322A3
              (en)
            
            * | 2003-07-09 | 2011-05-11 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds | 
        
          | CA2531732C
              (en) | 2003-07-09 | 2012-04-10 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds | 
        
          | US7485319B2
              (en)
            
            * | 2003-07-25 | 2009-02-03 | Warner Chilcott Company, Inc. | Doxycycline metal complex in a solid dosage form | 
        
          | CA2553510C
              (en)
            
            * | 2004-01-15 | 2012-09-25 | Paratek Pharmaceuticals, Inc. | Aromatic a-ring derivatives of tetracycline compounds | 
        
          | TWI261038B
              (en)
            
            * | 2004-08-11 | 2006-09-01 | Bo-Cheng Chen | Bicycle gear-shifting handgrip | 
        
          | AU2005299294B2
              (en) | 2004-10-25 | 2012-06-07 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines and methods of use thereof | 
        
          | EP2305637A3
              (en) | 2004-10-25 | 2011-09-21 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds | 
        
          | CN101128206A
              (zh)
            
            * | 2005-01-21 | 2008-02-20 | 沃纳奇尔科特公司 | 固体剂型形式的四环素类金属络合物 | 
        
          | AU2006210406C1
              (en) | 2005-02-04 | 2013-03-07 | Paratek Pharmaceuticals, Inc. | 11a, 12-derivatives of tetracycline compounds | 
        
          | US7919483B2
              (en)
            
            * | 2005-06-24 | 2011-04-05 | Medicis Pharmaceutical Corporation | Method for the treatment of acne | 
        
          | US9192615B2
              (en) | 2008-08-06 | 2015-11-24 | Medicis Pharmaceutical Corporation | Method for the treatment of acne and certain dosage forms thereof | 
        
          | US8252776B2
              (en) | 2007-04-02 | 2012-08-28 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne | 
        
          | US8722650B1
              (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms | 
        
          | US7544373B2
              (en)
            
            * | 2007-04-02 | 2009-06-09 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne | 
        
          | US20080242642A1
              (en) | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne | 
        
          | US7541347B2
              (en)
            
            * | 2007-04-02 | 2009-06-02 | Medicis Pharmaceutical Coropration | Minocycline oral dosage forms for the treatment of acne | 
        
          | US20080241235A1
              (en)
            
            * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne | 
        
          | WO2007014154A2
              (en)
            
            * | 2005-07-21 | 2007-02-01 | Paratek Pharmaceuticals, Inc. | 10-substituted tetracyclines and methods of use thereof | 
        
          | EP2298324A1
              (en) | 2006-01-24 | 2011-03-23 | Paratek Pharmaceuticals, Inc. | Methods of increasing oral bioavailability of tetracyclines | 
        
          | WO2007120913A2
              (en)
            
            * | 2006-04-17 | 2007-10-25 | Teva Pharmaceutical Industries Ltd. | Isolation of tetracycline derivatives | 
        
          | PL2016045T3
              (pl)
            
            * | 2006-04-24 | 2015-04-30 | Teva Pharma | Krystaliczna postać tygecykliny i sposoby jej otrzymywania | 
        
          | US8198470B2
              (en)
            
            * | 2006-04-24 | 2012-06-12 | Teva Pharmaceutical Industries Ltd. | Crystalline form II of tigecycline and processes for preparation thereof | 
        
          | EP2029749A2
              (en)
            
            * | 2006-05-15 | 2009-03-04 | Paratek Pharmaceuticals, Inc. | Methods of regulating expression of genes or of gene products using substituted tetracycline compounds | 
        
          | US8440646B1
              (en) | 2006-10-11 | 2013-05-14 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of Bacillus anthracis infections | 
        
          | ES2463457T3
              (es) | 2006-12-21 | 2014-05-28 | Paratek Pharmaceuticals, Inc. | Derivados de la tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias | 
        
          | WO2008079363A2
              (en) | 2006-12-21 | 2008-07-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of inflammatory skin disorders | 
        
          | US20080241197A1
              (en)
            
            * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline dosage forms for the treatment of acne | 
        
          | WO2008127722A1
              (en)
            
            * | 2007-04-12 | 2008-10-23 | Paratek Pharmaceuticals, Inc. | Methods for treating spinal muscular atrophy using tetracycline compounds | 
        
          | CA2688662A1
              (en)
            
            * | 2007-04-27 | 2008-11-06 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing and purifying aminoalkyl tetracycline compounds | 
        
          | CA2693376A1
              (en) | 2007-07-06 | 2009-01-15 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing substituted tetracycline compounds | 
        
          | CA2717703A1
              (en)
            
            * | 2008-03-05 | 2009-09-11 | Paratek Pharmaceuticals, Inc. | Minocycline compounds and methods of use thereof | 
        
          | PT2271348T
              (pt) | 2008-03-28 | 2018-04-16 | Paratek Pharm Innc | Formulação de comprimido oral de composto de tetraciclina | 
        
          | WO2009128913A1
              (en)
            
            * | 2008-04-14 | 2009-10-22 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds | 
        
          | TW202021946A
              (zh) | 2008-05-19 | 2020-06-16 | 美商派洛泰克藥物股份有限公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 | 
        
          | CA2737470A1
              (en)
            
            * | 2008-09-19 | 2010-03-25 | Paratek Pharmaceuticals, Inc. | Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment | 
        
          | JP2012523438A
              (ja) | 2009-04-10 | 2012-10-04 | タフツ  メディカル  センター  インコーポレイテッド | メタロプロテイナーゼ−1(mmp−1)によるpar−1活性化 | 
        
          | EP2568987B1
              (en) | 2010-05-12 | 2016-11-16 | Rempex Pharmaceuticals, Inc. | Tetracycline compositions | 
        
          | JP6574572B2
              (ja) | 2011-05-12 | 2019-09-11 | パラテック ファーマシューティカルズ インコーポレイテッド | (4s,4as,5ar,12as)−4−ジメチルアミノ−3,10,12,12a−テトラヒドロキシ−7−[(メトキシ(メチル)アミノ)−メチル]−1,11−ジオキソ−1,4,4a,5,5a,6,11,12a−オクタヒドロ−ナフタセン−2−カルボン酸アミドの結晶塩及びそれを使用する方法 | 
        
          | US9561241B1
              (en) | 2011-06-28 | 2017-02-07 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for minocycline | 
        
          | WO2015021387A2
              (en)
            
            * | 2013-08-09 | 2015-02-12 | Britt George N | Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations | 
        
          | CN103536530A
              (zh)
            
            * | 2013-10-30 | 2014-01-29 | 王玉万 | 盐酸多西环素长效注射剂及制备方法 | 
        
          | BR112017020358A2
              (pt) | 2015-03-23 | 2018-07-17 | Biopharmx Inc | composição farmacêutica de tetraciclina para uso dermatológico | 
        
          | CN104721133B
              (zh)
            
            * | 2015-04-14 | 2018-05-18 | 四川美嘉龙生物科技有限公司 | 一种土霉素制剂及制备方法 | 
        
          | RU2019113715A
              (ru) | 2016-11-01 | 2020-12-03 | Паратек Фармасьютикалс, Инк. | 9-аминометилминоциклиновые соединения и их применение для лечениия внебольничной бактериальной пневмонии(вбп) | 
        
          | ES2962380T3
              (es) | 2017-07-21 | 2024-03-18 | Almirall Llc | Sareciclina para el tratamiento de lesiones de acné no inflamatorias | 
        
          | WO2019106036A1
              (en) | 2017-11-28 | 2019-06-06 | C-Lecta Gmbh | Method for producing trehalose employing a trehalose phosphorylase variant | 
        
          | US11426351B2
              (en) | 2019-12-26 | 2022-08-30 | Sunstar Inc. | Process for producing a pharmaceutical composition containing micro particles |