ZA753722B - Process for the preparation of analogues of daunomycin - Google Patents

Process for the preparation of analogues of daunomycin

Info

Publication number
ZA753722B
ZA753722B ZA00753722A ZA753722A ZA753722B ZA 753722 B ZA753722 B ZA 753722B ZA 00753722 A ZA00753722 A ZA 00753722A ZA 753722 A ZA753722 A ZA 753722A ZA 753722 B ZA753722 B ZA 753722B
Authority
ZA
South Africa
Prior art keywords
daunomycin
analogues
preparation
Prior art date
Application number
ZA00753722A
Other languages
English (en)
Inventor
L Bernardi
F Arcamone
B Patelli
Marco A Di
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of ZA753722B publication Critical patent/ZA753722B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA00753722A 1974-06-12 1975-06-10 Process for the preparation of analogues of daunomycin ZA753722B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2608374A GB1467383A (en) 1974-06-12 1974-06-12 Daunomycin analogues

Publications (1)

Publication Number Publication Date
ZA753722B true ZA753722B (en) 1976-09-29

Family

ID=10238087

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00753722A ZA753722B (en) 1974-06-12 1975-06-10 Process for the preparation of analogues of daunomycin

Country Status (17)

Country Link
US (1) US4046878A (me)
JP (1) JPS5840557B2 (me)
AT (1) AT337363B (me)
BE (1) BE830090A (me)
BG (1) BG61059B2 (me)
CH (1) CH611317A5 (me)
DE (2) DE2525633A1 (me)
DK (1) DK147304C (me)
ES (1) ES438431A1 (me)
FR (1) FR2274629A1 (me)
GB (1) GB1467383A (me)
HK (1) HK982A (me)
MY (1) MY103666A (me)
NL (1) NL173272C (me)
SE (1) SE423633B (me)
SU (1) SU645588A3 (me)
ZA (1) ZA753722B (me)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
US4161480A (en) * 1978-06-05 1979-07-17 G. D. Searle & Co. Intermediates for the synthesis of 4-demethoxydaunorubicin
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
BE884828A (fr) * 1979-08-20 1981-02-19 Hoffmann La Roche Derives de naphtacene
EP0024727B1 (en) * 1979-09-01 1982-05-26 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
ZA814722B (en) * 1980-07-18 1982-07-28 Hoffmann La Roche Novel anthracycline glycosides
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4564674A (en) * 1983-10-31 1986-01-14 Sagami Chemical Research Center Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4697005A (en) * 1985-03-20 1987-09-29 Ohio State University Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
JPS63191263U (me) * 1987-05-29 1988-12-09
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
DK0629209T3 (da) * 1992-03-02 1997-10-13 Pfizer Sukkerderivater af makrolider
US8252520B2 (en) * 2002-10-11 2012-08-28 Taivex Therapeutics Corporation Methods and compounds for inhibiting Hec1 activity for the treatment of proliferative diseases
AU2006207321B2 (en) 2005-01-21 2012-09-06 Astex Therapeutics Limited Pharmaceutical compounds
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
NZ593648A (en) * 2008-12-23 2013-09-27 Gilead Pharmasset Llc Nucleoside phosphoramidates
CL2009002206A1 (es) * 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
EA201100851A1 (ru) * 2008-12-23 2012-04-30 Фармассет, Инк. Аналоги нуклеозидов
TWI630916B (zh) 2009-11-13 2018-08-01 第一三共歐洲公司 供治療或預防人表皮生長因子受體－３（ｈｅｒ－３）相關疾病之藥料和方法
BR112012024884A2 (pt) 2010-03-31 2016-10-18 Gilead Pharmasset Llc síntese estereosseletiva de ativos contendo fósforo
WO2012018404A2 (en) 2010-08-06 2012-02-09 U3 Pharma Gmbh Use of her3 binding agents in prostate treatment
DE102011113652A1 (de) 2011-09-19 2013-03-21 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Idarubicinhydrochlorid
ES2673957T5 (es) 2011-10-03 2021-12-15 Croda Int Plc Nanopartículas, procedimiento para la preparación y utilización de las mismas como portadoras de moléculas anfipáticas o hidrofóbicas en el campo de la medicina, incluyendo el tratamiento del cáncer, y compuestos de tipo alimentario
AR095962A1 (es) 2013-04-01 2015-11-25 Moreinx Ab Nanopartículas, compuestas de esterol y saponina de quillaja saponaria molina, proceso para preparación y uso de las mismas como portadores para moléculas anfipáticas o hidrófobas en el campo de la medicina incluyendo tratamiento de cáncer y compuestos relacionados con alimentos
EP3669890A1 (en) 2018-12-18 2020-06-24 Croda International PLC Filamentous nanoparticles having vaccine adjuvant effect

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof

Also Published As

Publication number Publication date
BE830090A (fr) 1975-12-11
JPS518260A (me) 1976-01-23
NL173272B (nl) 1983-08-01
DE2525633C3 (me) 1979-10-18
DE19375027I2 (de) 2002-06-13
NL173272C (nl) 1984-01-02
SU645588A3 (ru) 1979-01-30
FR2274629A1 (fr) 1976-01-09
ATA437375A (de) 1976-10-15
SE7506589L (sv) 1975-12-15
US4046878A (en) 1977-09-06
DK147304B (da) 1984-06-12
FR2274629B1 (me) 1980-01-11
BG61059B2 (bg) 1996-09-30
NL7506745A (nl) 1975-12-16
GB1467383A (en) 1977-03-16
CH611317A5 (me) 1979-05-31
DE2525633B2 (me) 1979-03-01
SE423633B (sv) 1982-05-17
JPS5840557B2 (ja) 1983-09-06
AU8197975A (en) 1976-12-16
DK147304C (da) 1984-12-17
MY103666A (en) 1993-08-28
DE2525633A1 (de) 1976-01-02
AT337363B (de) 1977-06-27
DK256875A (da) 1975-12-13
HK982A (en) 1982-01-22
ES438431A1 (es) 1977-02-01

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