ZA752639B - Preparation of alpha-6-deoxy-5-hydroxy-tetracycline - Google Patents

Preparation of alpha-6-deoxy-5-hydroxy-tetracycline

Info

Publication number
ZA752639B
ZA752639B ZA00752639A ZA752639A ZA752639B ZA 752639 B ZA752639 B ZA 752639B ZA 00752639 A ZA00752639 A ZA 00752639A ZA 752639 A ZA752639 A ZA 752639A ZA 752639 B ZA752639 B ZA 752639B
Authority
ZA
South Africa
Prior art keywords
deoxy
tetracycline
alpha
hydroxy
preparation
Prior art date
Application number
ZA00752639A
Other languages
English (en)
Inventor
C Scanio
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA752639B publication Critical patent/ZA752639B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/461,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
ZA00752639A 1974-05-28 1975-04-23 Preparation of alpha-6-deoxy-5-hydroxy-tetracycline ZA752639B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US473791A US3907890A (en) 1974-05-28 1974-05-28 Preparation of alpha-6-deoxy-5-hydroxytetracycline

Publications (1)

Publication Number Publication Date
ZA752639B true ZA752639B (en) 1976-04-28

Family

ID=23880982

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00752639A ZA752639B (en) 1974-05-28 1975-04-23 Preparation of alpha-6-deoxy-5-hydroxy-tetracycline

Country Status (33)

Country Link
US (1) US3907890A (da)
JP (1) JPS585185B2 (da)
AR (1) AR204864A1 (da)
AT (1) AT338421B (da)
BE (1) BE829344A (da)
BG (1) BG29427A3 (da)
CA (1) CA1029719A (da)
CH (1) CH602592A5 (da)
CS (1) CS176141B2 (da)
DE (1) DE2520546A1 (da)
DK (1) DK145877C (da)
EG (1) EG11666A (da)
ES (1) ES437047A1 (da)
FI (1) FI58910C (da)
FR (1) FR2272978B1 (da)
GB (1) GB1478587A (da)
HK (1) HK28579A (da)
HU (1) HU169913B (da)
IE (1) IE41554B1 (da)
IL (1) IL47118A (da)
IN (1) IN141263B (da)
KE (1) KE2935A (da)
LU (1) LU72566A1 (da)
MY (1) MY7900244A (da)
NL (1) NL180310C (da)
NO (1) NO146199C (da)
PH (1) PH10678A (da)
PL (1) PL96623B1 (da)
RO (1) RO72528A (da)
SE (1) SE421612B (da)
SU (1) SU578865A3 (da)
YU (1) YU39319B (da)
ZA (1) ZA752639B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US4218340A (en) * 1975-11-19 1980-08-19 Eastman Kodak Company Nickel and cobalt containing carbonylation catalyst compositions for the production of carboxylic acids and their esters
US4374752A (en) * 1981-06-30 1983-02-22 Union Carbide Corporation Catalyst and process for the conversion of methanol to acetaldehyde
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6220097A (ja) * 1985-07-19 1987-01-28 能美防災株式会社 蓄積型火災受信機
JPS6425298A (en) * 1987-07-21 1989-01-27 Yazaki Corp Gas leakage warning device
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
EP0391005B1 (en) * 1989-04-03 1991-10-16 Ranbaxy Laboratories, Ltd. Process for the production of alpha-6-deoxytetracyclines
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (da) * 1960-05-23 1966-05-25
GB1182353A (en) * 1966-02-07 1970-02-25 Montedison Spa Cobalt Hydrocarbonyls
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3692864A (en) * 1970-09-30 1972-09-19 Texaco Inc Hydrogenation process utilizing homogeneous metal catalysts
US3717585A (en) * 1971-01-08 1973-02-20 Phillips Petroleum Co Promoted trihydrocarbylphosphine modified carbonyl cobalt catalyst system

Also Published As

Publication number Publication date
LU72566A1 (da) 1976-03-17
BG29427A3 (en) 1980-11-14
YU39319B (en) 1984-10-31
HU169913B (da) 1977-02-28
IL47118A0 (en) 1975-06-25
ES437047A1 (es) 1977-01-16
GB1478587A (en) 1977-07-06
FR2272978B1 (da) 1978-06-09
CH602592A5 (da) 1978-07-31
FI751437A (da) 1975-11-29
KE2935A (en) 1979-03-30
DK145877C (da) 1983-09-12
NL180310C (nl) 1987-02-02
FI58910C (fi) 1981-05-11
CS176141B2 (da) 1977-06-30
US3907890A (en) 1975-09-23
DK225075A (da) 1975-11-29
ATA359375A (de) 1976-12-15
NO751389L (da) 1975-12-01
BE829344A (fr) 1975-11-24
IE41554B1 (en) 1980-01-30
NO146199C (no) 1982-08-18
FR2272978A1 (da) 1975-12-26
NL7505943A (nl) 1975-12-02
SE7504140L (sv) 1975-12-01
FI58910B (fi) 1981-01-30
CA1029719A (en) 1978-04-18
EG11666A (en) 1978-03-29
PH10678A (en) 1977-08-05
DE2520546A1 (de) 1975-12-04
AT338421B (de) 1977-08-25
NO146199B (no) 1982-05-10
IL47118A (en) 1978-01-31
NL180310B (nl) 1986-09-01
IN141263B (da) 1977-02-05
DK145877B (da) 1983-03-28
IE41554L (en) 1975-11-28
AR204864A1 (es) 1976-03-05
PL96623B1 (pl) 1978-01-31
SU578865A3 (ru) 1977-10-30
YU132875A (en) 1982-05-31
JPS50160261A (da) 1975-12-25
RO72528A (ro) 1981-11-04
HK28579A (en) 1979-05-11
JPS585185B2 (ja) 1983-01-29
MY7900244A (en) 1979-12-31
SE421612B (sv) 1982-01-18

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