AT338421B - Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid - Google Patents

Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid

Info

Publication number
AT338421B
AT338421B AT359375A AT359375A AT338421B AT 338421 B AT338421 B AT 338421B AT 359375 A AT359375 A AT 359375A AT 359375 A AT359375 A AT 359375A AT 338421 B AT338421 B AT 338421B
Authority
AT
Austria
Prior art keywords
hydroxyteetracyclin
desoxy
alfa
hydrochloride
preparation
Prior art date
Application number
AT359375A
Other languages
English (en)
Other versions
ATA359375A (de
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA359375A publication Critical patent/ATA359375A/de
Application granted granted Critical
Publication of AT338421B publication Critical patent/AT338421B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/461,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
AT359375A 1974-05-28 1975-05-12 Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid AT338421B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US473791A US3907890A (en) 1974-05-28 1974-05-28 Preparation of alpha-6-deoxy-5-hydroxytetracycline

Publications (2)

Publication Number Publication Date
ATA359375A ATA359375A (de) 1976-12-15
AT338421B true AT338421B (de) 1977-08-25

Family

ID=23880982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT359375A AT338421B (de) 1974-05-28 1975-05-12 Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid

Country Status (33)

Country Link
US (1) US3907890A (de)
JP (1) JPS585185B2 (de)
AR (1) AR204864A1 (de)
AT (1) AT338421B (de)
BE (1) BE829344A (de)
BG (1) BG29427A3 (de)
CA (1) CA1029719A (de)
CH (1) CH602592A5 (de)
CS (1) CS176141B2 (de)
DE (1) DE2520546A1 (de)
DK (1) DK145877C (de)
EG (1) EG11666A (de)
ES (1) ES437047A1 (de)
FI (1) FI58910C (de)
FR (1) FR2272978B1 (de)
GB (1) GB1478587A (de)
HK (1) HK28579A (de)
HU (1) HU169913B (de)
IE (1) IE41554B1 (de)
IL (1) IL47118A (de)
IN (1) IN141263B (de)
KE (1) KE2935A (de)
LU (1) LU72566A1 (de)
MY (1) MY7900244A (de)
NL (1) NL180310C (de)
NO (1) NO146199C (de)
PH (1) PH10678A (de)
PL (1) PL96623B1 (de)
RO (1) RO72528A (de)
SE (1) SE421612B (de)
SU (1) SU578865A3 (de)
YU (1) YU39319B (de)
ZA (1) ZA752639B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US4218340A (en) * 1975-11-19 1980-08-19 Eastman Kodak Company Nickel and cobalt containing carbonylation catalyst compositions for the production of carboxylic acids and their esters
US4374752A (en) * 1981-06-30 1983-02-22 Union Carbide Corporation Catalyst and process for the conversion of methanol to acetaldehyde
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6220097A (ja) * 1985-07-19 1987-01-28 能美防災株式会社 蓄積型火災受信機
JPS6425298A (en) * 1987-07-21 1989-01-27 Yazaki Corp Gas leakage warning device
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
EP0391005B1 (de) * 1989-04-03 1991-10-16 Ranbaxy Laboratories, Ltd. Verfahren zur Herstellung von alpha-6-Deoxytetracyclinen
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (de) * 1960-05-23 1966-05-25
GB1182353A (en) * 1966-02-07 1970-02-25 Montedison Spa Cobalt Hydrocarbonyls
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3692864A (en) * 1970-09-30 1972-09-19 Texaco Inc Hydrogenation process utilizing homogeneous metal catalysts
US3717585A (en) * 1971-01-08 1973-02-20 Phillips Petroleum Co Promoted trihydrocarbylphosphine modified carbonyl cobalt catalyst system

Also Published As

Publication number Publication date
LU72566A1 (de) 1976-03-17
BG29427A3 (en) 1980-11-14
YU39319B (en) 1984-10-31
HU169913B (de) 1977-02-28
IL47118A0 (en) 1975-06-25
ES437047A1 (es) 1977-01-16
GB1478587A (en) 1977-07-06
FR2272978B1 (de) 1978-06-09
CH602592A5 (de) 1978-07-31
FI751437A (de) 1975-11-29
KE2935A (en) 1979-03-30
DK145877C (da) 1983-09-12
NL180310C (nl) 1987-02-02
FI58910C (fi) 1981-05-11
CS176141B2 (de) 1977-06-30
US3907890A (en) 1975-09-23
ZA752639B (en) 1976-04-28
DK225075A (da) 1975-11-29
ATA359375A (de) 1976-12-15
NO751389L (de) 1975-12-01
BE829344A (fr) 1975-11-24
IE41554B1 (en) 1980-01-30
NO146199C (no) 1982-08-18
FR2272978A1 (de) 1975-12-26
NL7505943A (nl) 1975-12-02
SE7504140L (sv) 1975-12-01
FI58910B (fi) 1981-01-30
CA1029719A (en) 1978-04-18
EG11666A (en) 1978-03-29
PH10678A (en) 1977-08-05
DE2520546A1 (de) 1975-12-04
NO146199B (no) 1982-05-10
IL47118A (en) 1978-01-31
NL180310B (nl) 1986-09-01
IN141263B (de) 1977-02-05
DK145877B (da) 1983-03-28
IE41554L (en) 1975-11-28
AR204864A1 (es) 1976-03-05
PL96623B1 (pl) 1978-01-31
SU578865A3 (ru) 1977-10-30
YU132875A (en) 1982-05-31
JPS50160261A (de) 1975-12-25
RO72528A (ro) 1981-11-04
HK28579A (en) 1979-05-11
JPS585185B2 (ja) 1983-01-29
MY7900244A (en) 1979-12-31
SE421612B (sv) 1982-01-18

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee