ATA359375A - Verfahren zur herstellung von alfa-6-desoxy-5-hydroxytetracyclin und dessen hydrochlorids - Google Patents

Verfahren zur herstellung von alfa-6-desoxy-5-hydroxytetracyclin und dessen hydrochlorids

Info

Publication number
ATA359375A
ATA359375A AT753593A AT359375A ATA359375A AT A359375 A ATA359375 A AT A359375A AT 753593 A AT753593 A AT 753593A AT 359375 A AT359375 A AT 359375A AT A359375 A ATA359375 A AT A359375A
Authority
AT
Austria
Prior art keywords
hydroxyteetracyclin
desoxy
alfa
hydrochloride
preparation
Prior art date
Application number
AT753593A
Other languages
English (en)
Other versions
AT338421B (de
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ATA359375A publication Critical patent/ATA359375A/de
Application granted granted Critical
Publication of AT338421B publication Critical patent/AT338421B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/461,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT359375A 1974-05-28 1975-05-12 Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid AT338421B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US473791A US3907890A (en) 1974-05-28 1974-05-28 Preparation of alpha-6-deoxy-5-hydroxytetracycline

Publications (2)

Publication Number Publication Date
ATA359375A true ATA359375A (de) 1976-12-15
AT338421B AT338421B (de) 1977-08-25

Family

ID=23880982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT359375A AT338421B (de) 1974-05-28 1975-05-12 Verfahren zur herstellung von alfa-6-desoxy-5- hydroxytetracyclin und dessen hydrochlorid

Country Status (33)

Country Link
US (1) US3907890A (de)
JP (1) JPS585185B2 (de)
AR (1) AR204864A1 (de)
AT (1) AT338421B (de)
BE (1) BE829344A (de)
BG (1) BG29427A3 (de)
CA (1) CA1029719A (de)
CH (1) CH602592A5 (de)
CS (1) CS176141B2 (de)
DE (1) DE2520546A1 (de)
DK (1) DK145877C (de)
EG (1) EG11666A (de)
ES (1) ES437047A1 (de)
FI (1) FI58910C (de)
FR (1) FR2272978B1 (de)
GB (1) GB1478587A (de)
HK (1) HK28579A (de)
HU (1) HU169913B (de)
IE (1) IE41554B1 (de)
IL (1) IL47118A (de)
IN (1) IN141263B (de)
KE (1) KE2935A (de)
LU (1) LU72566A1 (de)
MY (1) MY7900244A (de)
NL (1) NL180310C (de)
NO (1) NO146199C (de)
PH (1) PH10678A (de)
PL (1) PL96623B1 (de)
RO (1) RO72528A (de)
SE (1) SE421612B (de)
SU (1) SU578865A3 (de)
YU (1) YU39319B (de)
ZA (1) ZA752639B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US4218340A (en) * 1975-11-19 1980-08-19 Eastman Kodak Company Nickel and cobalt containing carbonylation catalyst compositions for the production of carboxylic acids and their esters
US4374752A (en) * 1981-06-30 1983-02-22 Union Carbide Corporation Catalyst and process for the conversion of methanol to acetaldehyde
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6220097A (ja) * 1985-07-19 1987-01-28 能美防災株式会社 蓄積型火災受信機
JPS6425298A (en) * 1987-07-21 1989-01-27 Yazaki Corp Gas leakage warning device
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (de) * 1960-05-23 1966-05-25
GB1182353A (en) * 1966-02-07 1970-02-25 Montedison Spa Cobalt Hydrocarbonyls
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3692864A (en) * 1970-09-30 1972-09-19 Texaco Inc Hydrogenation process utilizing homogeneous metal catalysts
US3717585A (en) * 1971-01-08 1973-02-20 Phillips Petroleum Co Promoted trihydrocarbylphosphine modified carbonyl cobalt catalyst system

Also Published As

Publication number Publication date
CH602592A5 (de) 1978-07-31
IL47118A0 (en) 1975-06-25
JPS50160261A (de) 1975-12-25
NO146199C (no) 1982-08-18
SE7504140L (sv) 1975-12-01
DE2520546A1 (de) 1975-12-04
YU39319B (en) 1984-10-31
IE41554L (en) 1975-11-28
DK145877C (da) 1983-09-12
JPS585185B2 (ja) 1983-01-29
FR2272978B1 (de) 1978-06-09
IE41554B1 (en) 1980-01-30
PH10678A (en) 1977-08-05
DK225075A (da) 1975-11-29
ES437047A1 (es) 1977-01-16
RO72528A (ro) 1981-11-04
CA1029719A (en) 1978-04-18
US3907890A (en) 1975-09-23
AR204864A1 (es) 1976-03-05
BE829344A (fr) 1975-11-24
NO751389L (de) 1975-12-01
CS176141B2 (de) 1977-06-30
MY7900244A (en) 1979-12-31
DK145877B (da) 1983-03-28
FI58910B (fi) 1981-01-30
LU72566A1 (de) 1976-03-17
BG29427A3 (en) 1980-11-14
PL96623B1 (pl) 1978-01-31
NL180310C (nl) 1987-02-02
HK28579A (en) 1979-05-11
SU578865A3 (ru) 1977-10-30
NL7505943A (nl) 1975-12-02
AT338421B (de) 1977-08-25
GB1478587A (en) 1977-07-06
IN141263B (de) 1977-02-05
FR2272978A1 (de) 1975-12-26
SE421612B (sv) 1982-01-18
ZA752639B (en) 1976-04-28
NL180310B (nl) 1986-09-01
FI58910C (fi) 1981-05-11
HU169913B (de) 1977-02-28
YU132875A (en) 1982-05-31
EG11666A (en) 1978-03-29
IL47118A (en) 1978-01-31
NO146199B (no) 1982-05-10
KE2935A (en) 1979-03-30
FI751437A (de) 1975-11-29

Similar Documents

Publication Publication Date Title
DD127731A5 (de) Verfahren zur herstellung von cephalosporansaeurederivaten
ATA966275A (de) Verfahren zur herstellung von p-benzochinondiketalen
ATA359375A (de) Verfahren zur herstellung von alfa-6-desoxy-5-hydroxytetracyclin und dessen hydrochlorids
ATA600375A (de) Verfahren zur herstellung von neuen 7-methoxy-6-thiatetracyclinen und deren salzen
AT333774B (de) Verfahren zur herstellung von 3-phenylpyridazonen
AT333959B (de) Verfahren zur herstellung von neuen n- (benzolsulfonyl) -5-o-desosaminylerythromycilamin-derivaten
DD128562A5 (de) Verfahren zur herstellung von 7-methoxy-cephalosporinen und deren salzen
ATA44576A (de) Verfahren zur herstellung von n- (alfa-alkoxyathyl)-carbonsaureamiden
AT342057B (de) Verfahren zur herstellung von neuen 3-piperazino-isochinolinen und deren salzen
DD122962A5 (de) Verfahren zur herstellung von halogenanthrachinonen
AT346502B (de) Verfahren zur herstellung von neuen n- substituierten 8-beta-aminoaethylergolin-i- derivaten und deren salzen
AT341672B (de) Verfahren zur herstellung von 3-methylencephamsulfoxiden
AT343120B (de) Verfahren zur herstellung von 6-chlor-2-chlormethyl-4-phenylchinazolin-3-oxid
AT345836B (de) Verfahren zur herstellung von neuen 4- diphenylbutyl-1-piperidinen und ihren salzen
ATA132075A (de) Verfahren zur herstellung von neuen azatetracyclen und ihren salzen
DE2316050A1 (de) Verfahren zur herstellung von 2-hydroxyaethylimino-diacetonitril und 2-hydroxyaethylimino-diacetaten
ATA975975A (de) Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen
DD122986A1 (de) Verfahren zur herstellung von polyesteralkoholen
ATA436876A (de) Verfahren zur herstellung von neuen triazolopyridazinen und ihren salzen
AT335063B (de) Verfahren zur herstellung von d(-)-alfa-amino-p-hydroxybenzylpenicillin
AT344675B (de) Verfahren zur herstellung von 3-fluor-dl-alanin
DD122973A5 (de) Verfahren zur herstellung von 4a-aryl-transdecahydroisochinolinen
AT343652B (de) Verfahren zur herstellung von neuen 2-aryl-4-cyanmethyl -5- methylimidazolen und ihren salzen
ATA851675A (de) Verfahren zur herstellung von 1-phenyl-2-glycinamidoathanolen- (1) und von deren salzen
AT326633B (de) Verfahren zur herstellung von neuen 2-aminomethyl-4-alkyl- oder -cycloalkyl-6-trihalogenmethylphenolen und deren salzen

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee