ZA202002080B - Glp-2 analogs and peptibodies for administration before, during or after surgery - Google Patents
Glp-2 analogs and peptibodies for administration before, during or after surgeryInfo
- Publication number
- ZA202002080B ZA202002080B ZA2020/02080A ZA202002080A ZA202002080B ZA 202002080 B ZA202002080 B ZA 202002080B ZA 2020/02080 A ZA2020/02080 A ZA 2020/02080A ZA 202002080 A ZA202002080 A ZA 202002080A ZA 202002080 B ZA202002080 B ZA 202002080B
- Authority
- ZA
- South Africa
- Prior art keywords
- glp
- analogs
- surgery
- small intestine
- during
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762582055P | 2017-11-06 | 2017-11-06 | |
| PCT/US2018/059175 WO2019090209A1 (en) | 2017-11-06 | 2018-11-05 | Glp-2 analogs and peptibodies for administration before during, or after surgery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202002080B true ZA202002080B (en) | 2025-11-26 |
Family
ID=66332372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2020/02080A ZA202002080B (en) | 2017-11-06 | 2020-05-04 | Glp-2 analogs and peptibodies for administration before, during or after surgery |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11660328B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3706774A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7296958B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102825098B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN111629745A (cg-RX-API-DMAC7.html) |
| AR (1) | AR113835A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2018360744A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112020008936A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3079523A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL274098B2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2020004620A (cg-RX-API-DMAC7.html) |
| TW (1) | TW201922279A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2019090209A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA202002080B (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111182916A (zh) * | 2017-08-22 | 2020-05-19 | 夏尔-Nps医药品有限公司 | Glp-2融合多肽及用于治疗及预防胃肠病状的用途 |
| JP2022512688A (ja) * | 2018-10-24 | 2022-02-07 | シャイア－エヌピーエス ファーマシューティカルズ インコーポレイテッド | Ｇｌｐ－２融合ポリペプチドならびに消化管の状態の処置および予防のための使用 |
| KR20220150270A (ko) | 2019-10-07 | 2022-11-10 | 칼리오페, 인크. | Gpr119 효능제 |
| CA3173731A1 (en) | 2020-02-28 | 2021-09-02 | Kallyope, Inc. | Gpr40 agonists |
| WO2021198196A1 (en) * | 2020-03-30 | 2021-10-07 | Zealand Pharma A/S | Glp-1/glp-2 dual agonists |
| CA3178994A1 (en) | 2020-05-19 | 2021-11-25 | Iyassu Sebhat | Ampk activators |
| WO2021263040A1 (en) * | 2020-06-26 | 2021-12-30 | Shire-Nps Pharmaceuticals, Inc. | Stable peptibody formulations |
| WO2021263039A1 (en) | 2020-06-26 | 2021-12-30 | Kallyope, Inc. | Ampk activators |
| CN115636876A (zh) * | 2021-07-20 | 2023-01-24 | 重庆派金生物科技有限公司 | 胰高血糖素样肽-2突变体的定向化学偶联物及其应用 |
| CN117467025B (zh) * | 2023-12-28 | 2024-04-16 | 上海鼎新基因科技有限公司 | 一种抗vegf和补体双功能融合蛋白及其应用 |
| WO2025181330A1 (en) * | 2024-02-29 | 2025-09-04 | Vectivbio Ag | Dosage regimens for glucagon-like peptide 2 (glp-2) analogs |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5197012B2 (ja) | 2004-11-01 | 2013-05-15 | エヌピーエス ファーマシューティカルズ インコーポレイテッド | 大腸連続性を伴う短腸症候群患者の治療 |
| CA2616551A1 (en) | 2005-07-29 | 2007-02-15 | Amprotein Corporation | Chimeric therapeutic agents |
| WO2007067828A2 (en) * | 2005-10-24 | 2007-06-14 | Centocor, Inc. | Glp-2 mimetibodies, polypeptides, compositions, methods and uses |
| EP2076604A4 (en) | 2006-08-31 | 2009-09-02 | Centocor Ortho Biotech Inc | GLP-2 MIMIC BODIES, POLYPEPTIDES, COMPOSITIONS, PROCESSES AND USES |
| JP2008247789A (ja) | 2007-03-30 | 2008-10-16 | Kissei Pharmaceut Co Ltd | クローン病に伴う腸管狭窄の進展抑制用医薬組成物 |
| EP2755675B1 (en) | 2011-09-12 | 2018-06-06 | Amunix Operating Inc. | Glucagon-like peptide-2 compositions and methods of making and using same |
| US9458214B2 (en) * | 2011-09-26 | 2016-10-04 | Novartis Ag | Dual function fibroblast growth factor 21 proteins |
| KR101895047B1 (ko) | 2011-12-30 | 2018-09-06 | 한미사이언스 주식회사 | 면역글로불린 단편을 이용한 위치 특이적 글루카곤 유사 펩타이드-2 약물 결합체 |
| WO2013164484A1 (en) | 2012-05-03 | 2013-11-07 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| WO2015095684A1 (en) * | 2013-12-20 | 2015-06-25 | Indiana University Research And Technology Corporation | Lipidated incretin receptor ligand human immunoglobulin fc-region fusion polypeptides |
| KR101825048B1 (ko) | 2014-12-31 | 2018-02-05 | 주식회사 제넥신 | GLP 및 면역글로불린 하이브리드 Fc 융합 폴리펩타이드 및 이의 용도 |
-
2018
- 2018-11-05 WO PCT/US2018/059175 patent/WO2019090209A1/en not_active Ceased
- 2018-11-05 JP JP2020526107A patent/JP7296958B2/ja active Active
- 2018-11-05 BR BR112020008936-2A patent/BR112020008936A2/pt unknown
- 2018-11-05 EP EP18872377.9A patent/EP3706774A4/en active Pending
- 2018-11-05 AU AU2018360744A patent/AU2018360744A1/en not_active Abandoned
- 2018-11-05 US US16/761,606 patent/US11660328B2/en active Active
- 2018-11-05 CA CA3079523A patent/CA3079523A1/en active Pending
- 2018-11-05 KR KR1020207013387A patent/KR102825098B1/ko active Active
- 2018-11-05 IL IL274098A patent/IL274098B2/en unknown
- 2018-11-05 MX MX2020004620A patent/MX2020004620A/es unknown
- 2018-11-05 CN CN201880071791.3A patent/CN111629745A/zh active Pending
- 2018-11-06 TW TW107139266A patent/TW201922279A/zh unknown
- 2018-11-06 AR ARP180103232A patent/AR113835A1/es unknown
-
2020
- 2020-05-04 ZA ZA2020/02080A patent/ZA202002080B/en unknown
-
2023
- 2023-06-13 JP JP2023096692A patent/JP7752152B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL274098B1 (en) | 2024-08-01 |
| US11660328B2 (en) | 2023-05-30 |
| KR20200085763A (ko) | 2020-07-15 |
| MX2020004620A (es) | 2020-10-12 |
| EP3706774A4 (en) | 2021-09-08 |
| AU2018360744A1 (en) | 2020-05-07 |
| JP7296958B2 (ja) | 2023-06-23 |
| BR112020008936A2 (pt) | 2020-10-20 |
| JP2023107883A (ja) | 2023-08-03 |
| JP2021502389A (ja) | 2021-01-28 |
| AR113835A1 (es) | 2020-06-17 |
| TW201922279A (zh) | 2019-06-16 |
| US20210169986A1 (en) | 2021-06-10 |
| RU2020118172A (ru) | 2021-12-08 |
| WO2019090209A1 (en) | 2019-05-09 |
| IL274098A (en) | 2020-06-30 |
| JP7752152B2 (ja) | 2025-10-09 |
| CN111629745A (zh) | 2020-09-04 |
| KR102825098B1 (ko) | 2025-06-26 |
| IL274098B2 (en) | 2024-12-01 |
| EP3706774A1 (en) | 2020-09-16 |
| CA3079523A1 (en) | 2019-05-09 |
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