ZA201802126B - A neural cell line differentiated from hipscs by directed induction, a method for induction and the application thereof - Google Patents
A neural cell line differentiated from hipscs by directed induction, a method for induction and the application thereofInfo
- Publication number
- ZA201802126B ZA201802126B ZA2018/02126A ZA201802126A ZA201802126B ZA 201802126 B ZA201802126 B ZA 201802126B ZA 2018/02126 A ZA2018/02126 A ZA 2018/02126A ZA 201802126 A ZA201802126 A ZA 201802126A ZA 201802126 B ZA201802126 B ZA 201802126B
- Authority
- ZA
- South Africa
- Prior art keywords
- induction
- hipscs
- application
- cell line
- neural cell
- Prior art date
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710632172.4A CN107326013B (zh) | 2017-07-28 | 2017-07-28 | 定向诱导hiPSC分化后的神经细胞体系、诱导方法及应用 |
PCT/CN2017/096761 WO2019019223A1 (zh) | 2017-07-28 | 2017-08-10 | 定向诱导hiPSC分化后的神经细胞体系、诱导方法及应用 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA201802126B true ZA201802126B (en) | 2021-08-25 |
Family
ID=60227609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA2018/02126A ZA201802126B (en) | 2017-07-28 | 2018-04-03 | A neural cell line differentiated from hipscs by directed induction, a method for induction and the application thereof |
Country Status (3)
Country | Link |
---|---|
CN (4) | CN111793607B (zh) |
WO (1) | WO2019019223A1 (zh) |
ZA (1) | ZA201802126B (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108823164A (zh) * | 2018-07-24 | 2018-11-16 | 九三极恒生物医药科技江苏有限公司 | 诱导多能干细胞向神经祖细胞分化的无血清培养体系 |
CN111304167B (zh) * | 2018-12-12 | 2024-03-26 | 上海泉眼生物科技有限公司 | 人源脂肪干细胞来源的神经元前体细胞及其制备方法和应用 |
CN109674809B (zh) * | 2018-12-27 | 2022-08-09 | 吉林大学 | 一种包括miR-124-3P的组合物及其在诱导神经元形成的药物中的应用 |
CN110819593B (zh) * | 2019-10-22 | 2024-01-16 | 五邑大学 | 可定向诱导的、抗凋亡的多能干细胞及其制备方法与应用 |
CN110982788B (zh) * | 2019-12-25 | 2021-07-06 | 昆明医科大学 | 一种诱导卫星胶质细胞转分化为神经元的方法 |
CN112055746A (zh) * | 2020-05-19 | 2020-12-08 | 武汉睿健医药科技有限公司 | 一种感觉神经元细胞的无血清诱导方法 |
CN113615691B (zh) * | 2021-08-06 | 2022-06-17 | 南京农业大学 | 一种植物抗冷剂及其制备方法和应用 |
CN113774023B (zh) * | 2021-09-28 | 2022-11-25 | 中国食品药品检定研究院 | 人诱导多能干细胞诱导分化神经细胞评价模型的构建及其评价药物神经毒性的用途 |
CN114672455A (zh) * | 2022-03-25 | 2022-06-28 | 中山大学 | 一种利用多能干细胞诱导骨髓基质细胞的方法 |
CN115125209B (zh) * | 2022-08-31 | 2022-12-06 | 华科星河(北京)生物科技有限公司 | 一种从诱导多能干细胞诱导颈段脊髓神经干细胞的方法 |
CN115125210B (zh) * | 2022-08-31 | 2022-12-02 | 华科星河(北京)生物科技有限公司 | 从iPSC诱导的腰骶段脊髓神经干细胞的培养基与方法 |
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CN101029302B (zh) * | 2001-06-21 | 2011-03-30 | 杰龙公司 | 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞 |
CA2475288C (en) * | 2002-02-06 | 2014-09-02 | Sanbio, Inc. | Method of inducing differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells by introduction of notch gene |
CN1415747A (zh) * | 2002-11-23 | 2003-05-07 | 浙江大学 | 造血干/祖细胞体外分阶段共培养扩增技术 |
CN1446907A (zh) * | 2003-04-18 | 2003-10-08 | 中山大学中山医学院科技开发中心 | 药物诱导神经干细胞增殖和分化的方法及应用 |
CN1961068A (zh) * | 2004-02-06 | 2007-05-09 | 赛若代姆公司 | 骨髓基质细胞培养神经干细胞的方法和组合物 |
GB0505510D0 (en) * | 2004-06-09 | 2005-04-27 | Univ Edinburgh | Neural stem cells |
US20070087437A1 (en) * | 2005-10-14 | 2007-04-19 | Jifan Hu | Methods for rejuvenating cells in vitro and in vivo |
EP2175868B1 (en) * | 2007-08-15 | 2017-12-20 | SanBio, Inc. | Bone marrow derived cells for use in treating neural degeneration |
US8642334B2 (en) * | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
WO2010138002A1 (en) * | 2009-05-29 | 2010-12-02 | Auckland Uniservices Limited | Methods for producing neuronal cells and uses thereof |
US20120129835A1 (en) * | 2010-11-16 | 2012-05-24 | Salk Institute For Biological Studies | Schizophrenia methods and compositions |
TWI493034B (zh) * | 2011-12-14 | 2015-07-21 | Nat Univ Chung Hsing | Neuronal epithelial cells differentiated by universal stem cells and the medium used and their differentiation methods |
CN104487568B (zh) * | 2012-07-11 | 2017-08-15 | 爱姆斯坦生物技术公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
CN105264068A (zh) * | 2013-04-02 | 2016-01-20 | 三星生命公益财团 | Charcot-Marie-Tooth病的治疗剂的筛选方法以及为此所使用的自分化运动神经元 |
WO2014171824A1 (en) * | 2013-04-16 | 2014-10-23 | Universiteit Twente | Blastoid, cell line based artificial blastocyst |
CN105431525B (zh) * | 2013-04-17 | 2020-04-10 | 索尔克生物学研究所 | 用于神经细胞培养的培养基组合物 |
GB201318126D0 (en) * | 2013-10-14 | 2013-11-27 | Univ Cardiff | Neuronal Stem Cell Differentiation |
CN105940101A (zh) * | 2013-11-21 | 2016-09-14 | 纪念斯隆-凯特琳癌症中心 | 由人多能干细胞特化功能性颅基板衍生物 |
CN104031882B (zh) * | 2014-06-20 | 2017-03-01 | 上海安集协康生物技术股份有限公司 | 人神经干细胞体外定向诱导分化为多巴胺能神经元的方法 |
AU2015305515B2 (en) * | 2014-08-19 | 2020-12-03 | FUJIFILM Cellular Dynamics, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
AU2016233250C1 (en) * | 2015-03-16 | 2022-08-18 | Regeneron Pharmaceuticals, Inc. | Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception |
CN105274048A (zh) * | 2015-11-03 | 2016-01-27 | 中山大学中山眼科中心 | 一种可降解人iPSCs源性视网膜神经支架及其制作方法 |
CN105274049B (zh) * | 2015-11-03 | 2018-01-09 | 中山大学中山眼科中心 | 一种诱导人iPSc源性的3D视网膜定向分化为视网膜神经节细胞的方法 |
CN105420193B (zh) * | 2015-12-07 | 2019-04-09 | 中国科学院广州生物医药与健康研究院 | 分化培养基及其在制备神经干细胞中的用途 |
CN105331583B (zh) * | 2015-12-08 | 2019-01-29 | 广州医科大学附属第三医院 | 一种促进人诱导多能干细胞向神经元诱导分化的方法 |
CN106479977B (zh) * | 2016-08-29 | 2018-02-23 | 广东依浦赛生物科技有限公司 | 人源iPS干细胞体外定向分化为神经细胞的试剂盒及方法 |
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2017
- 2017-07-28 CN CN202010750543.0A patent/CN111793607B/zh active Active
- 2017-07-28 CN CN202010752115.1A patent/CN111793608B/zh active Active
- 2017-07-28 CN CN201710632172.4A patent/CN107326013B/zh active Active
- 2017-07-28 CN CN202010752137.8A patent/CN111849899B/zh active Active
- 2017-08-10 WO PCT/CN2017/096761 patent/WO2019019223A1/zh active Application Filing
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2018
- 2018-04-03 ZA ZA2018/02126A patent/ZA201802126B/en unknown
Also Published As
Publication number | Publication date |
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CN111849899B (zh) | 2022-06-14 |
CN107326013A (zh) | 2017-11-07 |
CN111849899A (zh) | 2020-10-30 |
CN107326013B (zh) | 2020-08-07 |
CN111793608A (zh) | 2020-10-20 |
CN111793607B (zh) | 2022-05-17 |
WO2019019223A1 (zh) | 2019-01-31 |
CN111793608B (zh) | 2022-05-17 |
CN111793607A (zh) | 2020-10-20 |
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