ZA201702634B - Therapeutic agent delivery device - Google Patents

Therapeutic agent delivery device

Info

Publication number
ZA201702634B
ZA201702634B ZA2017/02634A ZA201702634A ZA201702634B ZA 201702634 B ZA201702634 B ZA 201702634B ZA 2017/02634 A ZA2017/02634 A ZA 2017/02634A ZA 201702634 A ZA201702634 A ZA 201702634A ZA 201702634 B ZA201702634 B ZA 201702634B
Authority
ZA
South Africa
Prior art keywords
therapeutic agent
delivery device
agent delivery
therapeutic
delivery
Prior art date
Application number
ZA2017/02634A
Other languages
English (en)
Inventor
Mark C Tsai
Jr Brian M Gatton
Michael F Keane
Isaac J Khan
Brendan J Oberkircher
Daniel W Price
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of ZA201702634B publication Critical patent/ZA201702634B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053Media being expelled from injector by pressurised fluid or vacuum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3137Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3146Priming, e.g. purging, reducing backlash or clearance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3148Means for causing or aiding aspiration or plunger retraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2086Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M2005/3154Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M2039/1077Adapters, e.g. couplings adapting a connector to one or several other connectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0612Eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
ZA2017/02634A 2014-09-18 2017-04-12 Therapeutic agent delivery device ZA201702634B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462052043P 2014-09-18 2014-09-18
US201462052074P 2014-09-18 2014-09-18
US201462052038P 2014-09-18 2014-09-18
US201462052059P 2014-09-18 2014-09-18
US14/843,350 US10258502B2 (en) 2014-09-18 2015-09-02 Therapeutic agent delivery device
PCT/US2015/050394 WO2016044404A2 (en) 2014-09-18 2015-09-16 Therapeutic agent delivery device

Publications (1)

Publication Number Publication Date
ZA201702634B true ZA201702634B (en) 2019-06-26

Family

ID=55524718

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2017/02634A ZA201702634B (en) 2014-09-18 2017-04-12 Therapeutic agent delivery device

Country Status (14)

Country Link
US (2) US10258502B2 (OSRAM)
EP (1) EP3193987B1 (OSRAM)
JP (2) JP6772127B2 (OSRAM)
KR (1) KR102202183B1 (OSRAM)
CN (1) CN107223042B (OSRAM)
AU (1) AU2015317872B2 (OSRAM)
BR (1) BR112017005332B1 (OSRAM)
CA (1) CA2961529C (OSRAM)
MX (1) MX2017003616A (OSRAM)
PH (1) PH12017500502A1 (OSRAM)
RU (1) RU2704596C2 (OSRAM)
SG (1) SG11201702095XA (OSRAM)
WO (1) WO2016044404A2 (OSRAM)
ZA (1) ZA201702634B (OSRAM)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2871138T3 (es) 2014-02-12 2021-10-28 Gyroscope Therapeutics Ltd Aparato para la administración supracoroidea de agente terapéutico
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
EP3341058B1 (en) 2015-08-24 2020-07-08 Teleflex Medical Incorporated Dose divider syringe
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
JP2019510589A (ja) * 2016-04-08 2019-04-18 アラーガン、インコーポレイテッドAllergan,Incorporated 吸引及び注入デバイス
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11273072B2 (en) 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US10463797B2 (en) 2017-09-07 2019-11-05 URO-1, Inc. Incremental syringe
US11090438B2 (en) 2017-10-17 2021-08-17 Bobby Nourani Slanted syringe handle
CN111526906B (zh) * 2017-12-29 2023-01-31 贝克顿·迪金森公司 具有耐用和一次性部件的低成本注射器
US11097061B2 (en) 2018-02-09 2021-08-24 Icon Bioscience, Inc. Systems, kits and methods for loading and delivering a small volume dose from a syringe
EP3773375B1 (en) 2018-04-12 2023-04-12 New World Medical, Inc. Device for intraocular fluid injection
JP7374928B2 (ja) * 2018-05-22 2023-11-07 ケーシーアイ ライセンシング インコーポレイテッド 一体型多層創傷被覆材における空気経路を管理するためのシステム及び方法
JP2021531920A (ja) * 2018-08-02 2021-11-25 バード・ペリフェラル・バスキュラー・インコーポレーテッド 低傷性の外装を有する植え込み可能なポート配置システム
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
CN118948524A (zh) * 2019-10-11 2024-11-15 陀螺仪治疗学有限公司 用于注射器的剂量夹组件
USD987818S1 (en) 2019-12-04 2023-05-30 Bobby Nourani Syringe adaptor
WO2021188224A1 (en) * 2020-03-17 2021-09-23 Amgen Inc. Controlled dispense syringe
CN114929311B (zh) * 2020-03-24 2023-07-28 泰尔茂株式会社 注射器筒体用握把以及筒体组装体和注射器
USD960359S1 (en) 2020-06-19 2022-08-09 Bobby Nourani Syringe handle
EP3967341B1 (en) * 2020-09-10 2025-07-09 Fenwal, Inc. Syringe with syringe closure
USD987819S1 (en) 2021-02-18 2023-05-30 Bobby Nourani Syringe holder
DE102021112962A1 (de) * 2021-05-19 2022-11-24 F+K Innovationen Gmbh & Co. Kg BI-Dose-Vorrichtung
MX2024000527A (es) 2021-07-22 2024-02-02 Chengdu Origen Biotechnology Co Ltd Conjunto de inyeccion ocular, dispositivo de inyeccion y metodo de uso del mismo.
US20230125693A1 (en) * 2021-10-22 2023-04-27 Lisa Monique Staples Breathing circuit-to-laryngoscope adapter
US20250186252A1 (en) * 2022-03-07 2025-06-12 The Johns Hopkins University Method and system for delivery of therapeutics to eye
CN119562797A (zh) 2022-07-11 2025-03-04 基因泰克公司 经玻璃体视网膜下注射器
WO2024052733A1 (en) 2022-09-06 2024-03-14 Gyroscope Therapeutics Limited Apparatus for subretinal administration of therapeutic agent via dual-curved needle
KR20250138741A (ko) 2023-01-13 2025-09-22 제넨테크, 인크. 주사기용 용량 도킹 장치
TW202529711A (zh) 2023-09-29 2025-08-01 美商建南德克公司 眼插管導引器、施用器及標記器械
WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
WO2025217230A1 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Vectorized anti-complement antibodies and complement agents and administration thereof

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US287576A (en) * 1883-10-30 Sewing machine
US2875761A (en) 1956-10-01 1959-03-03 Norman D Helmer Multiple dosage syringe
US4267846A (en) * 1979-01-29 1981-05-19 Critikon, Inc. Controlled volume blood sampling syringe
US4231494A (en) * 1979-03-22 1980-11-04 Greenwood David L Syringe adaptor assembly
US4874385A (en) * 1987-12-16 1989-10-17 Sherwood Medical Company Plunger lock device
US5066276A (en) * 1988-06-21 1991-11-19 Alcon Laboratories, Inc. Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control
US5019037A (en) * 1989-07-06 1991-05-28 Alcon Laboratories, Inc. Pneumatic retinopexy injector
US5817075A (en) * 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5252064A (en) * 1991-02-19 1993-10-12 Teledyne Industries, Inc. Subgingival irrigator
US5601077A (en) * 1991-08-07 1997-02-11 Becton, Dickinson And Company Nasal syringe sprayer with removable dose limiting structure
US5653715A (en) 1993-03-09 1997-08-05 Chiron Vision Corporation Apparatus for preparing an intraocular lens for insertion
US5803918A (en) * 1993-05-06 1998-09-08 Becton Dickinson And Company Syringe for medicinal purposes
DE4339528C2 (de) * 1993-11-19 1995-09-07 Freudenberg Carl Fa Einwegspritze
JP3306796B2 (ja) * 1995-01-26 2002-07-24 大成化工株式会社 薬液が予備充填された注入筒向けガラスカートリッジ
US5964740A (en) 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
US6283951B1 (en) 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
IL124038A (en) 1995-10-13 2004-02-19 Transvascular Inc Apparatus for bypassing arterial obstructions and/or performing other transvascular procedures
US5887764A (en) * 1996-11-27 1999-03-30 Ennis, Iii; James F. Apparatus for a pressurized injector
US5975355A (en) * 1997-06-25 1999-11-02 Cecala; Ann Dosage unit measurer for syringe
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6200289B1 (en) 1998-04-10 2001-03-13 Milestone Scientific, Inc. Pressure/force computer controlled drug delivery system and the like
US6309374B1 (en) * 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6143004A (en) 1998-08-18 2000-11-07 Atrion Medical Products, Inc. Suturing device
US6162197A (en) 1998-12-22 2000-12-19 Mohammad; Owais Retractable needle assembly and method of making the same
JP3372886B2 (ja) 1999-02-18 2003-02-04 エスエムシー株式会社 管継手
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
DK1092447T3 (da) 1999-10-14 2004-05-10 Becton Dickinson Co Nasalafgivelsesindretning indbefattende en spröjtedyse
EP1221918B1 (en) 1999-10-21 2005-03-16 Alcon Inc. Sub-tenon drug delivery
US7357794B2 (en) 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US7122042B2 (en) 2001-03-15 2006-10-17 Lorusso Frank J Apparatuses and methods for transcleral cautery and subretinal drainage
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US6494863B1 (en) 2001-10-15 2002-12-17 Retractable Technologies, Inc. One-use retracting syringe with positive needle retention
AU2003213075A1 (en) 2002-02-14 2003-09-04 Henry J. Kaplan Subretinal implantation device and surgical cannulas for use therewith
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
AU2003279055A1 (en) 2002-09-29 2004-04-19 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US6997904B2 (en) * 2002-12-24 2006-02-14 Robert David Sculati Viscous fluid injection system
KR100473568B1 (ko) * 2003-01-25 2005-03-10 이희영 밀폐형 지방이식 시스템
US7329241B2 (en) 2003-02-14 2008-02-12 Valeant Pharmaceuticals North America Drug delivery system for administering an adjustable preset dose
US7220224B1 (en) * 2003-03-07 2007-05-22 Minu, Llc Retinal translocation and fixation using adhesive material
US20040199130A1 (en) 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
DE10326706A1 (de) * 2003-06-04 2005-01-05 Schott Ag Spritze, insbesondere für medizinische Anwendungen, sowie Verfahren zum Herstellen einer solchen
WO2005001079A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Soft tissue repair and regeneration using postpartum-derived cells
FR2858931B1 (fr) * 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
AR042539A1 (es) * 2003-12-18 2005-06-22 Jose Santiago Rolla Unidad para suministro de inyectables en forma manual o automatica
SG183072A1 (en) 2004-01-23 2012-08-30 Iscience Surgical Corp Composite ophthalmic microcannula
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
US8235256B2 (en) * 2004-02-12 2012-08-07 Kyphon Sarl Manual pump mechanism and delivery system
US20100173866A1 (en) * 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
US7601140B2 (en) * 2004-06-25 2009-10-13 Alcon, Inc. Syringe pressure applicator
JP2006010010A (ja) 2004-06-29 2006-01-12 Smc Corp 管継手
US20060047250A1 (en) 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
US20060173415A1 (en) 2005-01-11 2006-08-03 Christy Cummins Syringe adaptor
US7686788B2 (en) * 2005-03-03 2010-03-30 Boston Scientific Scimed, Inc. Catheter having a distal drug delivery unit and method of using same
ATE442172T1 (de) 2005-05-02 2009-09-15 Elastomeric Systems S L Spritze zur verabreichung mehrerer dosen mit injektionsnadel mit sterilisationsschutz
WO2007002304A2 (en) 2005-06-22 2007-01-04 Vnus Medical Technologies, Inc. Methods and apparatus for introducing tumescent fluid to body tissue
US9144645B2 (en) * 2005-09-21 2015-09-29 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
DE602007008562D1 (de) * 2006-06-13 2010-09-30 Nordson Corp Flüssigkeitsausgabespritze
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US20090124996A1 (en) * 2006-11-03 2009-05-14 Scott Heneveld Apparatus and methods for injecting high viscosity dermal fillers
JP2008142533A (ja) 2006-11-16 2008-06-26 Manii Kk トロカール
US20090018548A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Intraocular Lens Injection Device with Removable Cartridge
US20090018512A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Ophthalmic Injector
US20110207987A1 (en) 2009-11-02 2011-08-25 Salutaris Medical Devices, Inc. Methods And Devices For Delivering Appropriate Minimally-Invasive Extraocular Radiation
ES2579355T3 (es) 2008-01-07 2016-08-10 Salutaris Medical Devices, Inc Dispositivos para la administración extraocular mínimamente invasiva de radiación a la porción posterior del ojo
WO2009089409A2 (en) 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US20100081707A1 (en) * 2008-02-21 2010-04-01 Ali Robin R Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
US7976510B2 (en) * 2008-02-28 2011-07-12 Becton, Dickinson And Company Syringe with adjustable two piece plunger rod
CA2717441A1 (en) * 2008-03-05 2009-09-11 Ivantis, Inc. Methods and apparatus for treating glaucoma
JP2012500049A (ja) 2008-08-13 2012-01-05 シルク・ロード・メディカル・インコーポレイテッド 縫合糸送達デバイス
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
SG176067A1 (en) 2009-05-15 2011-12-29 Iscience Interventional Corp Methods and apparatus for sub-retinal catheterization
EP2437841B1 (en) 2009-06-05 2019-10-30 Cook Medical Technologies LLC Access sheath and needle assembly for delivering therapeutic material
US20110087173A1 (en) * 2009-10-12 2011-04-14 Sibbitt Jr Wilmer L Automatic syringes
CH702815A1 (de) * 2010-03-10 2011-09-15 Medmix Systems Ag Befüllvorrichtung zum Befüllen mindestens eines ersten Reservoirs eines Applikators.
SE535983C2 (sv) * 2010-04-20 2013-03-19 Noviscens Ab Spruta
US9526841B2 (en) * 2010-06-30 2016-12-27 Nipro Corporation Spraying device
CA2813060C (en) * 2010-10-01 2017-02-21 Bracco Imaging S.P.A. Finger-grip device for medical syringe or cartridge
CN104758118B (zh) 2010-10-15 2018-04-06 科尼尔赛德生物医学公司 用于进入眼睛的装置
LT2701773T (lt) * 2011-04-25 2019-07-10 Icon Bioscience, Inc. Injekcinio švirkšto dozės kreiptuvai
EP2701778B2 (en) 2011-04-28 2023-10-18 Biogen MA Inc. A limiter for a dispensing device
JP5695485B2 (ja) * 2011-04-28 2015-04-08 株式会社吉野工業所 注射器
WO2012157582A1 (ja) * 2011-05-13 2012-11-22 ニプロ株式会社 鼻腔投与容器
US8852165B2 (en) 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
US9629675B2 (en) 2011-10-19 2017-04-25 Confluent Medical Technologies, Inc. Tissue treatment device and related methods
US20130131633A1 (en) * 2011-11-18 2013-05-23 Allergan, Inc. Modular injection system and method for diluting an injectable fluid
JP6039190B2 (ja) * 2012-02-13 2016-12-07 株式会社ニデック 医療用器具
US9138530B2 (en) 2012-02-15 2015-09-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
CA2882184C (en) 2012-08-27 2021-09-07 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
US9132229B2 (en) * 2012-09-13 2015-09-15 Alcon Research, Ltd. System and method of priming a surgical cassette
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
EP4566672A3 (en) 2012-11-08 2025-08-13 Clearside Biomedical Inc. Methods for the treatment of ocular disease in human subjects
PL2732770T3 (pl) 2012-11-16 2016-12-30 Bezigłowe urządzenie do iniekcji
AU2014207245B2 (en) * 2013-01-15 2018-12-06 Heriot Eyecare Pty. Ltd. Method and device for treating retinal detachment
US20160022920A1 (en) * 2013-03-14 2016-01-28 Gavis Pharmaceuticals, Llc Syringe
JP6594869B2 (ja) 2013-08-02 2019-10-23 テル ハショメール メディカル リサーチ インフラストラクチュアー アンド サービス エルティーディー. 目に組成物を輸送するためのデバイス
US9795503B2 (en) * 2013-10-18 2017-10-24 Rodolfo Alfredo PEREZ GROSSMANN Method and apparatus for trabeculectomy and suprachoroidal shunt surgery
ES2871138T3 (es) 2014-02-12 2021-10-28 Gyroscope Therapeutics Ltd Aparato para la administración supracoroidea de agente terapéutico
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US9949874B2 (en) * 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
MX2016016836A (es) 2014-06-17 2017-07-27 Clearside Biomedical Inc Metodos y dispositivos para tratar trastornos oculares posteriores.
JP2017524419A (ja) 2014-06-20 2017-08-31 クリアサイド バイオメディカル,インコーポレイテッド 薬剤送達のための挿入深さを制御するための可変径カニューレ及び方法
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa

Also Published As

Publication number Publication date
BR112017005332B1 (pt) 2022-04-12
WO2016044404A3 (en) 2016-06-09
US20190183674A1 (en) 2019-06-20
US20160081849A1 (en) 2016-03-24
EP3193987A2 (en) 2017-07-26
SG11201702095XA (en) 2017-04-27
CA2961529A1 (en) 2016-03-24
CN107223042B (zh) 2020-02-21
MX2017003616A (es) 2018-01-24
US10258502B2 (en) 2019-04-16
JP2017527406A (ja) 2017-09-21
PH12017500502A1 (en) 2017-08-30
AU2015317872B2 (en) 2019-12-19
JP6953580B2 (ja) 2021-10-27
CA2961529C (en) 2021-08-31
US11337852B2 (en) 2022-05-24
KR20170056645A (ko) 2017-05-23
RU2704596C2 (ru) 2019-10-29
JP6772127B2 (ja) 2020-10-21
KR102202183B1 (ko) 2021-01-13
JP2020121196A (ja) 2020-08-13
WO2016044404A2 (en) 2016-03-24
AU2015317872A1 (en) 2017-04-06
RU2017113086A3 (OSRAM) 2019-06-14
BR112017005332A2 (pt) 2017-12-12
EP3193987B1 (en) 2020-02-26
CN107223042A (zh) 2017-09-29
RU2017113086A (ru) 2018-10-18

Similar Documents

Publication Publication Date Title
ZA201702634B (en) Therapeutic agent delivery device
IL255987B (en) Drug release device
IL250685A0 (en) Medicinal substance induces cytotoxicity
GB2531910B (en) Ophthalmic delivery device
IL249777A0 (en) Drug release device
IL250813A0 (en) Drug release device
HUE056904T2 (hu) Gyógyszertovábbító szerkezet
GB201515650D0 (en) Medicament delivery devices
GB201612516D0 (en) Medicament delivery device
GB201401587D0 (en) Therapeutic product delivery device
GB201506788D0 (en) Medicament delivery device
EP3389593C0 (en) MEDICAL DELIVERY DEVICE
GB201410816D0 (en) Therapeutic agents
HUE052701T2 (hu) Gyógyszeradagoló eszközök
PT3622986T (pt) Dispositivo de aplicação de medicamento
GB201619562D0 (en) Medicament delivery device
PT3099353T (pt) Dispositivo para administração de medicamentos
GB201401588D0 (en) Therapeutic product delivery device
GB201410817D0 (en) Therapeutic agents
GB201619556D0 (en) Medicament delivery device
GB201410815D0 (en) Therapeutic agents
IL249789A0 (en) Drug release device
GB2537639B (en) Medicament delivery device
GB201607778D0 (en) Drug delivery device
GB2570052B (en) Therapy delivery device