ZA201602703B - A molecular marker of plasmodium falciparum artemisinin resistance - Google Patents
A molecular marker of plasmodium falciparum artemisinin resistanceInfo
- Publication number
- ZA201602703B ZA201602703B ZA2016/02703A ZA201602703A ZA201602703B ZA 201602703 B ZA201602703 B ZA 201602703B ZA 2016/02703 A ZA2016/02703 A ZA 2016/02703A ZA 201602703 A ZA201602703 A ZA 201602703A ZA 201602703 B ZA201602703 B ZA 201602703B
- Authority
- ZA
- South Africa
- Prior art keywords
- molecular marker
- plasmodium falciparum
- artemisinin resistance
- artemisinin
- resistance
- Prior art date
Links
- 241000223960 Plasmodium falciparum Species 0.000 title 1
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title 1
- 229960004191 artemisinin Drugs 0.000 title 1
- 229930101531 artemisinin Natural products 0.000 title 1
- 239000003147 molecular marker Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
- G01N2333/445—Plasmodium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361904651P | 2013-11-15 | 2013-11-15 | |
| US201462062439P | 2014-10-10 | 2014-10-10 | |
| PCT/IB2014/002910 WO2015071759A1 (en) | 2013-11-15 | 2014-11-14 | A molecular marker of plasmodium falciparum artemisinin resistance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201602703B true ZA201602703B (en) | 2019-12-18 |
Family
ID=52440720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2016/02703A ZA201602703B (en) | 2013-11-15 | 2016-04-19 | A molecular marker of plasmodium falciparum artemisinin resistance |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10900093B2 (https=) |
| EP (1) | EP3068903B1 (https=) |
| JP (2) | JP6667445B2 (https=) |
| KR (1) | KR102283408B1 (https=) |
| CN (1) | CN105940115B (https=) |
| AU (1) | AU2014349828B2 (https=) |
| BR (1) | BR112016011046A2 (https=) |
| ES (1) | ES2720728T3 (https=) |
| WO (1) | WO2015071759A1 (https=) |
| ZA (1) | ZA201602703B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3497237B1 (en) | 2016-08-10 | 2022-05-04 | Institut Pasteur | Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria |
| CN109504791A (zh) * | 2018-12-29 | 2019-03-22 | 潮州市人民医院 | 用于检测疟原虫青蒿素耐药性相关k13基因突变的试剂盒 |
| CN109897901A (zh) * | 2019-02-27 | 2019-06-18 | 四川国际旅行卫生保健中心 | 检测恶性疟原虫k13基因突变位点的特异性引物组及其应用 |
| CN109797207A (zh) * | 2019-02-27 | 2019-05-24 | 四川国际旅行卫生保健中心 | 一种检测恶性疟原虫k13基因四个抗性突变位点的方法 |
| CN112592395A (zh) * | 2020-12-11 | 2021-04-02 | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 一种恶性疟原虫RIFIN重组蛋白PfRIFIN-54的构建、制备及用途 |
Family Cites Families (42)
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| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5242794A (en) | 1984-12-13 | 1993-09-07 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5333675C1 (en) | 1986-02-25 | 2001-05-01 | Perkin Elmer Corp | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
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| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| WO1989001050A1 (en) | 1987-07-31 | 1989-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Selective amplification of target polynucleotide sequences |
| JP2650159B2 (ja) | 1988-02-24 | 1997-09-03 | アクゾ・ノベル・エヌ・ベー | 核酸増幅方法 |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
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| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| CA2005589C (en) | 1988-12-16 | 2001-02-06 | Akzo Nobel Nv | Self-sustained, sequence replication system |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
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| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
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| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
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| CN100535125C (zh) * | 2007-06-28 | 2009-09-02 | 中国疾病预防控制中心寄生虫病预防控制所 | 用于扩增恶性疟原虫药物抗性相关基因的多重pcr引物及方法 |
-
2014
- 2014-11-14 WO PCT/IB2014/002910 patent/WO2015071759A1/en not_active Ceased
- 2014-11-14 KR KR1020167015777A patent/KR102283408B1/ko not_active Expired - Fee Related
- 2014-11-14 BR BR112016011046A patent/BR112016011046A2/pt not_active IP Right Cessation
- 2014-11-14 EP EP14833371.9A patent/EP3068903B1/en active Active
- 2014-11-14 US US15/036,064 patent/US10900093B2/en active Active
- 2014-11-14 ES ES14833371T patent/ES2720728T3/es active Active
- 2014-11-14 JP JP2016553749A patent/JP6667445B2/ja active Active
- 2014-11-14 AU AU2014349828A patent/AU2014349828B2/en active Active
- 2014-11-14 CN CN201480062113.2A patent/CN105940115B/zh active Active
-
2016
- 2016-04-19 ZA ZA2016/02703A patent/ZA201602703B/en unknown
-
2019
- 2019-12-05 JP JP2019220442A patent/JP2020043873A/ja active Pending
-
2020
- 2020-12-16 US US17/124,478 patent/US11732312B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10900093B2 (en) | 2021-01-26 |
| US11732312B2 (en) | 2023-08-22 |
| US20210198755A1 (en) | 2021-07-01 |
| JP2020043873A (ja) | 2020-03-26 |
| EP3068903A1 (en) | 2016-09-21 |
| WO2015071759A1 (en) | 2015-05-21 |
| CN105940115B (zh) | 2021-07-06 |
| US20160289774A1 (en) | 2016-10-06 |
| CA2928014A1 (en) | 2015-05-21 |
| ES2720728T3 (es) | 2019-07-24 |
| EP3068903B1 (en) | 2019-02-13 |
| JP2016537030A (ja) | 2016-12-01 |
| AU2014349828A1 (en) | 2016-05-26 |
| HK1225757A1 (en) | 2017-09-15 |
| JP6667445B2 (ja) | 2020-03-18 |
| KR102283408B1 (ko) | 2021-07-29 |
| WO2015071759A9 (en) | 2016-06-23 |
| BR112016011046A2 (pt) | 2019-01-29 |
| CN105940115A (zh) | 2016-09-14 |
| AU2014349828B2 (en) | 2021-01-28 |
| KR20160119753A (ko) | 2016-10-14 |
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