CN105940115B - 恶性疟原虫青蒿素耐药性的分子标记物 - Google Patents

恶性疟原虫青蒿素耐药性的分子标记物 Download PDF

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CN105940115B
CN105940115B CN201480062113.2A CN201480062113A CN105940115B CN 105940115 B CN105940115 B CN 105940115B CN 201480062113 A CN201480062113 A CN 201480062113A CN 105940115 B CN105940115 B CN 105940115B
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nucleic acid
plasmodium
seq
propeller
kit
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CN105940115A (zh
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F·阿里埃
O·普加朗
D·迈纳德
F·贝诺特-维卡尔
J·贝格哈恩
B·维特科斯基
J-C·巴拉勒
C·博契尔
N·基姆
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Institut Pasteur
Institut Pasteur du Cambodge
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Institut Pasteur du Cambodge
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
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    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G01N2333/445—Plasmodium
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
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  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201480062113.2A 2013-11-15 2014-11-14 恶性疟原虫青蒿素耐药性的分子标记物 Active CN105940115B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361904651P 2013-11-15 2013-11-15
US61/904,651 2013-11-15
US201462062439P 2014-10-10 2014-10-10
US62/062,439 2014-10-10
PCT/IB2014/002910 WO2015071759A1 (en) 2013-11-15 2014-11-14 A molecular marker of plasmodium falciparum artemisinin resistance

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CN105940115A CN105940115A (zh) 2016-09-14
CN105940115B true CN105940115B (zh) 2021-07-06

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US (2) US10900093B2 (https=)
EP (1) EP3068903B1 (https=)
JP (2) JP6667445B2 (https=)
KR (1) KR102283408B1 (https=)
CN (1) CN105940115B (https=)
AU (1) AU2014349828B2 (https=)
BR (1) BR112016011046A2 (https=)
ES (1) ES2720728T3 (https=)
WO (1) WO2015071759A1 (https=)
ZA (1) ZA201602703B (https=)

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Publication number Priority date Publication date Assignee Title
EP3497237B1 (en) 2016-08-10 2022-05-04 Institut Pasteur Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria
CN109504791A (zh) * 2018-12-29 2019-03-22 潮州市人民医院 用于检测疟原虫青蒿素耐药性相关k13基因突变的试剂盒
CN109897901A (zh) * 2019-02-27 2019-06-18 四川国际旅行卫生保健中心 检测恶性疟原虫k13基因突变位点的特异性引物组及其应用
CN109797207A (zh) * 2019-02-27 2019-05-24 四川国际旅行卫生保健中心 一种检测恶性疟原虫k13基因四个抗性突变位点的方法
CN112592395A (zh) * 2020-12-11 2021-04-02 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) 一种恶性疟原虫RIFIN重组蛋白PfRIFIN-54的构建、制备及用途

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US10900093B2 (en) 2021-01-26
US11732312B2 (en) 2023-08-22
US20210198755A1 (en) 2021-07-01
JP2020043873A (ja) 2020-03-26
EP3068903A1 (en) 2016-09-21
WO2015071759A1 (en) 2015-05-21
US20160289774A1 (en) 2016-10-06
CA2928014A1 (en) 2015-05-21
ES2720728T3 (es) 2019-07-24
EP3068903B1 (en) 2019-02-13
JP2016537030A (ja) 2016-12-01
AU2014349828A1 (en) 2016-05-26
HK1225757A1 (en) 2017-09-15
JP6667445B2 (ja) 2020-03-18
KR102283408B1 (ko) 2021-07-29
ZA201602703B (en) 2019-12-18
WO2015071759A9 (en) 2016-06-23
BR112016011046A2 (pt) 2019-01-29
CN105940115A (zh) 2016-09-14
AU2014349828B2 (en) 2021-01-28
KR20160119753A (ko) 2016-10-14

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