ZA201304208B - Neprilysin inhibitors - Google Patents

Neprilysin inhibitors

Info

Publication number
ZA201304208B
ZA201304208B ZA2013/04208A ZA201304208A ZA201304208B ZA 201304208 B ZA201304208 B ZA 201304208B ZA 2013/04208 A ZA2013/04208 A ZA 2013/04208A ZA 201304208 A ZA201304208 A ZA 201304208A ZA 201304208 B ZA201304208 B ZA 201304208B
Authority
ZA
South Africa
Prior art keywords
neprilysin inhibitors
neprilysin
inhibitors
Prior art date
Application number
ZA2013/04208A
Other languages
English (en)
Inventor
Cameron J Smith
Roland Gendron
Adam D Hughes
Melissa Fleury
Ryan Hudson
Original Assignee
Theravance Biopharma R & D Ip Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Biopharma R & D Ip Llc filed Critical Theravance Biopharma R & D Ip Llc
Publication of ZA201304208B publication Critical patent/ZA201304208B/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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