ZA201202683B - Azilsartan organic amine salts,preparation method and use thereof - Google Patents
Azilsartan organic amine salts,preparation method and use thereofInfo
- Publication number
- ZA201202683B ZA201202683B ZA2012/02683A ZA201202683A ZA201202683B ZA 201202683 B ZA201202683 B ZA 201202683B ZA 2012/02683 A ZA2012/02683 A ZA 2012/02683A ZA 201202683 A ZA201202683 A ZA 201202683A ZA 201202683 B ZA201202683 B ZA 201202683B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- organic amine
- amine salts
- azilsartan organic
- azilsartan
- Prior art date
Links
- 239000005485 Azilsartan Substances 0.000 title 1
- -1 amine salts Chemical class 0.000 title 1
- KGSXMPPBFPAXLY-UHFFFAOYSA-N azilsartan Chemical compound CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C1=NOC(=O)N1 KGSXMPPBFPAXLY-UHFFFAOYSA-N 0.000 title 1
- 229960002731 azilsartan Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910246554 | 2009-11-30 | ||
| PCT/CN2010/079222 WO2011063764A1 (zh) | 2009-11-30 | 2010-11-29 | 阿齐沙坦有机胺盐及其制备方法和用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201202683B true ZA201202683B (en) | 2013-08-28 |
Family
ID=44065877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/02683A ZA201202683B (en) | 2009-11-30 | 2012-04-13 | Azilsartan organic amine salts,preparation method and use thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120238606A1 (enExample) |
| EP (1) | EP2508522A4 (enExample) |
| JP (1) | JP2013512199A (enExample) |
| CN (1) | CN102548988B (enExample) |
| AU (1) | AU2010324249B2 (enExample) |
| BR (1) | BR112012012484A2 (enExample) |
| CA (1) | CA2782224A1 (enExample) |
| MX (1) | MX2012005776A (enExample) |
| RU (1) | RU2554947C2 (enExample) |
| WO (1) | WO2011063764A1 (enExample) |
| ZA (1) | ZA201202683B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5981940B2 (ja) * | 2011-01-20 | 2016-08-31 | ジエンス ハンセン ファーマセウティカル カンパニー リミテッド | アジルサルタン有機アミン塩、その製造方法及び使用 |
| EP2760859A1 (en) | 2011-09-30 | 2014-08-06 | Sunshine Lake Pharma Co., Ltd | Crystalline forms of azilsartan and preparation and uses thereof |
| JP2017036215A (ja) * | 2013-12-27 | 2017-02-16 | トーアエイヨー株式会社 | アンジオテンシンｉｉ受容体拮抗物質の塩 |
| CN105037341B (zh) * | 2014-04-04 | 2019-12-03 | 江苏豪森药业集团有限公司 | 阿齐沙坦醇铵晶型及其制备方法 |
| CN105503848A (zh) * | 2014-10-13 | 2016-04-20 | 江苏豪森药业集团有限公司 | 阿齐沙坦有机胺盐复合物及其制备方法和用途 |
| CZ2014702A3 (cs) | 2014-10-15 | 2016-04-27 | Zentiva, K.S. | Způsob přípravy vysoce čistého azilsartanu |
| KR102220011B1 (ko) * | 2020-05-15 | 2021-02-25 | 대봉엘에스 주식회사 | 친환경 용매를 이용한 아질사탄의 제조방법 및 이에 관한 핵심 중간체 화합물 |
| KR102862852B1 (ko) * | 2022-09-19 | 2025-09-22 | 대봉엘에스 주식회사 | 안지오텐신 ⅱ 길항제로서의 아질사르탄 디시클로헥실아민 및 이를 유효성분으로 하는 심혈관질환 치료 또는 예방용 약학적 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA924666B (en) * | 1991-06-27 | 1993-12-24 | Takeda Chemical Industries Ltd | Heterocyclic compounds, their production and use |
| TW251288B (enExample) * | 1991-06-27 | 1995-07-11 | Takeda Dharm Industry Co Ltd | |
| JP2004523569A (ja) * | 2001-03-08 | 2004-08-05 | メルク エンド カムパニー インコーポレーテッド | 抗高血圧薬とコレステロール吸収阻害薬の併用療法 |
| EP1452176A4 (en) * | 2001-12-03 | 2009-01-21 | Takeda Pharmaceutical | AGENTS FOR IMPROVING THE STATE OF RESISTANCE OF INSULIN |
| JP4484427B2 (ja) * | 2001-12-03 | 2010-06-16 | 武田薬品工業株式会社 | インスリン抵抗性改善剤 |
| CN101035524A (zh) * | 2004-10-07 | 2007-09-12 | 武田药品工业株式会社 | 预防或治疗代谢综合征的药剂 |
| UY29155A1 (es) * | 2004-10-07 | 2006-02-24 | Takeda Pharmaceutical | Un agente para la profilaxis o tratamietno del sindrome metabolico |
| WO2006064228A2 (en) * | 2004-12-17 | 2006-06-22 | Astrazeneca Ab | Thiazolopyramidine compounds for the modulation of chemokine receptor activity |
-
2010
- 2010-11-29 RU RU2012124332/04A patent/RU2554947C2/ru active
- 2010-11-29 WO PCT/CN2010/079222 patent/WO2011063764A1/zh not_active Ceased
- 2010-11-29 CA CA2782224A patent/CA2782224A1/en not_active Abandoned
- 2010-11-29 AU AU2010324249A patent/AU2010324249B2/en not_active Ceased
- 2010-11-29 CN CN2010800449716A patent/CN102548988B/zh not_active Expired - Fee Related
- 2010-11-29 US US13/512,652 patent/US20120238606A1/en not_active Abandoned
- 2010-11-29 BR BR112012012484A patent/BR112012012484A2/pt not_active IP Right Cessation
- 2010-11-29 JP JP2012540278A patent/JP2013512199A/ja active Pending
- 2010-11-29 EP EP10832671.1A patent/EP2508522A4/en not_active Withdrawn
- 2010-11-29 MX MX2012005776A patent/MX2012005776A/es not_active Application Discontinuation
-
2012
- 2012-04-13 ZA ZA2012/02683A patent/ZA201202683B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2554947C2 (ru) | 2015-07-10 |
| WO2011063764A1 (zh) | 2011-06-03 |
| EP2508522A1 (en) | 2012-10-10 |
| US20120238606A1 (en) | 2012-09-20 |
| CN102548988B (zh) | 2013-10-23 |
| RU2012124332A (ru) | 2014-01-10 |
| AU2010324249A1 (en) | 2012-05-03 |
| AU2010324249B2 (en) | 2014-08-28 |
| MX2012005776A (es) | 2012-06-13 |
| CA2782224A1 (en) | 2011-06-03 |
| BR112012012484A2 (pt) | 2016-04-12 |
| CN102548988A (zh) | 2012-07-04 |
| EP2508522A4 (en) | 2013-05-08 |
| JP2013512199A (ja) | 2013-04-11 |
| HK1164310A1 (en) | 2012-09-21 |
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