BR112012012484A2 - "sais de amina orgânicos de azilsartan, método de preparação e uso dos mesmos". - Google Patents
"sais de amina orgânicos de azilsartan, método de preparação e uso dos mesmos".Info
- Publication number
- BR112012012484A2 BR112012012484A2 BR112012012484A BR112012012484A BR112012012484A2 BR 112012012484 A2 BR112012012484 A2 BR 112012012484A2 BR 112012012484 A BR112012012484 A BR 112012012484A BR 112012012484 A BR112012012484 A BR 112012012484A BR 112012012484 A2 BR112012012484 A2 BR 112012012484A2
- Authority
- BR
- Brazil
- Prior art keywords
- azilsartan
- preparation
- organic amine
- amine salts
- machines
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000005485 Azilsartan Substances 0.000 title 1
- -1 amine salts Chemical class 0.000 title 1
- KGSXMPPBFPAXLY-UHFFFAOYSA-N azilsartan Chemical class CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C1=NOC(=O)N1 KGSXMPPBFPAXLY-UHFFFAOYSA-N 0.000 title 1
- 229960002731 azilsartan Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910246554 | 2009-11-30 | ||
| PCT/CN2010/079222 WO2011063764A1 (zh) | 2009-11-30 | 2010-11-29 | 阿齐沙坦有机胺盐及其制备方法和用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012012484A2 true BR112012012484A2 (pt) | 2016-04-12 |
Family
ID=44065877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012012484A BR112012012484A2 (pt) | 2009-11-30 | 2010-11-29 | "sais de amina orgânicos de azilsartan, método de preparação e uso dos mesmos". |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120238606A1 (enExample) |
| EP (1) | EP2508522A4 (enExample) |
| JP (1) | JP2013512199A (enExample) |
| CN (1) | CN102548988B (enExample) |
| AU (1) | AU2010324249B2 (enExample) |
| BR (1) | BR112012012484A2 (enExample) |
| CA (1) | CA2782224A1 (enExample) |
| MX (1) | MX2012005776A (enExample) |
| RU (1) | RU2554947C2 (enExample) |
| WO (1) | WO2011063764A1 (enExample) |
| ZA (1) | ZA201202683B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2666773B1 (en) * | 2011-01-20 | 2017-07-26 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Organic amine salts of azilsartan, preparation method and use thereof |
| JP2014530805A (ja) | 2011-09-30 | 2014-11-20 | スンシネ ルアケ プハルマ カンパニー リミテッド | アジルサルタンの結晶形並びにその製造及び使用 |
| JP2017036215A (ja) * | 2013-12-27 | 2017-02-16 | トーアエイヨー株式会社 | アンジオテンシンｉｉ受容体拮抗物質の塩 |
| CN105037341B (zh) * | 2014-04-04 | 2019-12-03 | 江苏豪森药业集团有限公司 | 阿齐沙坦醇铵晶型及其制备方法 |
| CN105503848A (zh) * | 2014-10-13 | 2016-04-20 | 江苏豪森药业集团有限公司 | 阿齐沙坦有机胺盐复合物及其制备方法和用途 |
| CZ2014702A3 (cs) | 2014-10-15 | 2016-04-27 | Zentiva, K.S. | Způsob přípravy vysoce čistého azilsartanu |
| KR102220011B1 (ko) * | 2020-05-15 | 2021-02-25 | 대봉엘에스 주식회사 | 친환경 용매를 이용한 아질사탄의 제조방법 및 이에 관한 핵심 중간체 화합물 |
| KR102862852B1 (ko) * | 2022-09-19 | 2025-09-22 | 대봉엘에스 주식회사 | 안지오텐신 ⅱ 길항제로서의 아질사르탄 디시클로헥실아민 및 이를 유효성분으로 하는 심혈관질환 치료 또는 예방용 약학적 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA924666B (en) * | 1991-06-27 | 1993-12-24 | Takeda Chemical Industries Ltd | Heterocyclic compounds, their production and use |
| TW251288B (enExample) * | 1991-06-27 | 1995-07-11 | Takeda Dharm Industry Co Ltd | |
| EP1389114A2 (en) * | 2001-03-08 | 2004-02-18 | Merck & Co., Inc. | Antihypertensive agent and cholesterol absorption inhibitor combination therapy |
| WO2003047573A1 (en) * | 2001-12-03 | 2003-06-12 | Takeda Chemical Industries, Ltd. | Insulin resistance improving agents |
| JP4484427B2 (ja) * | 2001-12-03 | 2010-06-16 | 武田薬品工業株式会社 | インスリン抵抗性改善剤 |
| CN101035524A (zh) * | 2004-10-07 | 2007-09-12 | 武田药品工业株式会社 | 预防或治疗代谢综合征的药剂 |
| US20070270477A1 (en) * | 2004-10-07 | 2007-11-22 | Takeda Pharmaceutical Company Limited | Agent for Prophylaxis or Treatment of Metabolic Syndrome |
| JP2008524186A (ja) * | 2004-12-17 | 2008-07-10 | アストラゼネカ・アクチエボラーグ | ケモカイン受容体活性の調節のためのチアゾロピラミジン化合物 |
-
2010
- 2010-11-29 CN CN2010800449716A patent/CN102548988B/zh not_active Expired - Fee Related
- 2010-11-29 CA CA2782224A patent/CA2782224A1/en not_active Abandoned
- 2010-11-29 RU RU2012124332/04A patent/RU2554947C2/ru active
- 2010-11-29 EP EP10832671.1A patent/EP2508522A4/en not_active Withdrawn
- 2010-11-29 BR BR112012012484A patent/BR112012012484A2/pt not_active IP Right Cessation
- 2010-11-29 MX MX2012005776A patent/MX2012005776A/es not_active Application Discontinuation
- 2010-11-29 AU AU2010324249A patent/AU2010324249B2/en not_active Ceased
- 2010-11-29 JP JP2012540278A patent/JP2013512199A/ja active Pending
- 2010-11-29 WO PCT/CN2010/079222 patent/WO2011063764A1/zh not_active Ceased
- 2010-11-29 US US13/512,652 patent/US20120238606A1/en not_active Abandoned
-
2012
- 2012-04-13 ZA ZA2012/02683A patent/ZA201202683B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010324249A1 (en) | 2012-05-03 |
| AU2010324249B2 (en) | 2014-08-28 |
| HK1164310A1 (en) | 2012-09-21 |
| CA2782224A1 (en) | 2011-06-03 |
| CN102548988A (zh) | 2012-07-04 |
| MX2012005776A (es) | 2012-06-13 |
| US20120238606A1 (en) | 2012-09-20 |
| RU2012124332A (ru) | 2014-01-10 |
| CN102548988B (zh) | 2013-10-23 |
| JP2013512199A (ja) | 2013-04-11 |
| ZA201202683B (en) | 2013-08-28 |
| WO2011063764A1 (zh) | 2011-06-03 |
| EP2508522A4 (en) | 2013-05-08 |
| RU2554947C2 (ru) | 2015-07-10 |
| EP2508522A1 (en) | 2012-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |