ZA201003131B - Anti-rsv g protein antibodies - Google Patents
Anti-rsv g protein antibodiesInfo
- Publication number
- ZA201003131B ZA201003131B ZA2010/03131A ZA201003131A ZA201003131B ZA 201003131 B ZA201003131 B ZA 201003131B ZA 2010/03131 A ZA2010/03131 A ZA 2010/03131A ZA 201003131 A ZA201003131 A ZA 201003131A ZA 201003131 B ZA201003131 B ZA 201003131B
- Authority
- ZA
- South Africa
- Prior art keywords
- rsv
- protein antibodies
- antibodies
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/11011—Alpharetrovirus, e.g. avian leucosis virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46907P | 2007-10-25 | 2007-10-25 | |
| US8940108P | 2008-08-15 | 2008-08-15 | |
| PCT/US2008/081175 WO2009055711A2 (en) | 2007-10-25 | 2008-10-24 | Anti-rsv g protein antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201003131B true ZA201003131B (en) | 2011-03-30 |
Family
ID=40580419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/03131A ZA201003131B (en) | 2007-10-25 | 2010-05-04 | Anti-rsv g protein antibodies |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7736648B2 (https=) |
| EP (1) | EP2214711B1 (https=) |
| JP (2) | JP5808536B2 (https=) |
| KR (1) | KR101671452B1 (https=) |
| CN (1) | CN101808663B (https=) |
| AU (1) | AU2008316703B2 (https=) |
| BR (1) | BRPI0819210A2 (https=) |
| CA (1) | CA2703667C (https=) |
| IL (1) | IL205257A (https=) |
| MX (1) | MX2010004482A (https=) |
| NZ (1) | NZ585589A (https=) |
| RU (1) | RU2526517C2 (https=) |
| WO (1) | WO2009055711A2 (https=) |
| ZA (1) | ZA201003131B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4874547B2 (ja) * | 2002-11-26 | 2012-02-15 | ギリアード サイエンシーズ， インコーポレイテッド | 勾配によるリポソームへの薬物充填方法 |
| BRPI0819210A2 (pt) * | 2007-10-25 | 2015-06-23 | Trellis Bioscience Inc | Anticorpos de proteína g anti-rsv |
| US9718876B2 (en) | 2011-11-17 | 2017-08-01 | Aimm Therapeutics B.V. | RSV G protein specific antibodies |
| ES2668104T3 (es) * | 2011-12-28 | 2018-05-16 | Immunoqure Ag | Procedimiento de aislamiento de anticuerpos humanos |
| US10131709B2 (en) | 2011-12-28 | 2018-11-20 | Immunoqure Ag | Nucleic acid molecules encoding monoclonal antibodies specific for IL-22 |
| WO2013119419A1 (en) | 2012-02-08 | 2013-08-15 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
| TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法 |
| WO2014170257A1 (en) * | 2013-04-15 | 2014-10-23 | Crucell Holland B.V. | Human antibodies binding to rsv g protein |
| CN111303278B (zh) * | 2013-04-15 | 2022-09-06 | 扬森疫苗与预防公司 | 结合到rsv g蛋白的人类抗体 |
| EA035846B1 (ru) * | 2013-04-15 | 2020-08-20 | Янссен Вэксинс Энд Превеншн Б.В. | Антитела человека, связывающиеся с g-белком rsv |
| JP2017512208A (ja) * | 2014-02-10 | 2017-05-18 | アイジーエム バイオサイエンス， インコーポレイテッド | ＩｇＡ多重特異性結合分子 |
| CN103911389A (zh) * | 2014-04-09 | 2014-07-09 | 南昌大学 | 一种检测人呼吸道合胞病毒抗体的g和f蛋白的制备方法 |
| SI3227339T1 (sl) | 2014-12-05 | 2022-02-28 | Memorial Sloan-Kettering Cancer Center | Himerni antigenski receptorji, ki ciljajo na receptor, povezan z G-proteinom, in njihova uporaba |
| EP3227324A4 (en) | 2014-12-05 | 2018-08-29 | Memorial Sloan Kettering Cancer Center | Antibodies targeting g-protein coupled receptor and methods of use |
| CN106496324B (zh) * | 2015-11-30 | 2020-01-14 | 天津昊免生物技术有限公司 | 一种抗呼吸道合胞病毒的全人源抗体 |
| CN105542003B (zh) * | 2016-03-01 | 2019-12-06 | 苏州博泰神州生物技术有限公司 | 一种针对rsv粘附g蛋白表面抗原的全人源单克隆抗体 |
| JP7127859B2 (ja) | 2016-11-09 | 2022-08-30 | ノース カロライナ ステート ユニバーシティ | キメラタンパク質を用いたアレルギー疾患の治療 |
| SG11201906682YA (en) | 2017-01-27 | 2019-08-27 | Ngm Biopharmaceuticals Inc | Glucagon receptor binding proteins and methods of use thereof |
| CA3079604A1 (en) * | 2017-10-13 | 2019-04-18 | Trellis Bioscience, Llc | Conformational epitopes in respiratory syncytial virus g protein central conserved region |
| WO2019183437A1 (en) | 2018-03-23 | 2019-09-26 | North Carolina State University | Methods and compositions for antibody to high affinity receptor for ige |
| US10961315B2 (en) | 2018-07-27 | 2021-03-30 | Ngm Biopharmaceuticals, Inc. | Method of treating type I diabetes by administering a combination of a glucagon receptor antagonist and an anti-CD3 antibody |
| EP3833677A4 (en) * | 2018-08-08 | 2022-04-27 | Trellis Bioscience, Inc. | IMPROVED RSV PASSIVE AND ACTIVE VACCINES |
| AU2020227545B2 (en) | 2019-02-28 | 2023-10-19 | Km Biologics Co., Ltd. | RSV F/G chimeric vaccine |
| WO2021046390A1 (en) | 2019-09-06 | 2021-03-11 | Silgan White Cap LLC | Tethered, hinged closure |
| EP4031171A1 (en) * | 2019-09-20 | 2022-07-27 | Universiteit Antwerpen | A novel human respiratory syncytial virus strain and its use |
| KR20220122656A (ko) | 2019-12-06 | 2022-09-02 | 주노 쎄러퓨티크스 인코퍼레이티드 | Ｇｐｒｃ5ｄ-표적화 결합 도메인에 대한 항-이디오타입 항체 및 관련 조성물 및 방법 |
| EP4429966A4 (en) | 2021-11-08 | 2026-01-14 | Silgan White Cap LLC | PROJECTION ON THE NECK OF A CONTAINER |
| WO2024027708A1 (zh) * | 2022-08-02 | 2024-02-08 | 诺纳生物（苏州）有限公司 | Msln抗体药物偶联物 |
| WO2025106427A1 (en) * | 2023-11-14 | 2025-05-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing and protective monoclonal antibodies against respiratory syncytial virus (rsv) |
| WO2025194126A1 (en) * | 2024-03-15 | 2025-09-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Respiratory syncytial virus (rsv) g and f antibodies with high rsv-neutralizing potency |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0705109B2 (en) * | 1993-05-25 | 2004-01-02 | American Cyanamid Company | Adjuvants for vaccines against respiratory syncytial virus |
| US6020182A (en) * | 1996-07-12 | 2000-02-01 | Connaught Laboratories Limited | Subunit respiratory syncytial virus vaccine preparation |
| FR2766192B1 (fr) * | 1997-07-17 | 2001-07-13 | Pf Medicament | Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie |
| US6642062B2 (en) | 1998-09-03 | 2003-11-04 | Trellis Bioinformatics, Inc. | Multihued labels |
| US7083950B2 (en) | 1998-09-25 | 2006-08-01 | Regeneron Pharmaceuticals, Inc. | High affinity fusion proteins and therapeutic and diagnostic methods for use |
| EP1638603A1 (en) | 1999-01-22 | 2006-03-29 | The Government of the United States represented by the Secretary of the Department of Health and Human Services | Methods for the prevention and treatment of diseases caused by an inflammatory response mediated by endogenous substance p by using anti-substance p antibodies |
| DE60136381D1 (de) * | 2000-10-18 | 2008-12-11 | Us Gov Health & Human Serv | Zusammensetzungen und verfahren zur modulierung von rsv-infektionen und -immunität |
| US7413868B2 (en) | 2003-11-05 | 2008-08-19 | Trellis Bioscience, Inc. | Use of particulate labels in bioanalyte detection methods |
| JP4736037B2 (ja) * | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| CN1986569A (zh) * | 2005-12-23 | 2007-06-27 | 首都儿科研究所 | 人源抗呼吸道合胞病毒中和性基因工程Fab抗体 |
| WO2007094423A1 (ja) * | 2006-02-15 | 2007-08-23 | Evec Incorporated | ヒトサイトメガロウイルスに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| JP2009528828A (ja) | 2006-03-06 | 2009-08-13 | シムフォゲン・アクティーゼルスカブ | 消化器多核体ウイルス感染症の治療のための組み換えポリクローナル抗体 |
| WO2008008858A2 (en) | 2006-07-12 | 2008-01-17 | Trellis Bioscience, Inc. | Cellspot™ applications |
| BRPI0819210A2 (pt) * | 2007-10-25 | 2015-06-23 | Trellis Bioscience Inc | Anticorpos de proteína g anti-rsv |
-
2008
- 2008-10-24 BR BRPI0819210-3A patent/BRPI0819210A2/pt not_active IP Right Cessation
- 2008-10-24 RU RU2010120879/10A patent/RU2526517C2/ru not_active IP Right Cessation
- 2008-10-24 EP EP08841063.4A patent/EP2214711B1/en active Active
- 2008-10-24 AU AU2008316703A patent/AU2008316703B2/en active Active
- 2008-10-24 JP JP2010531283A patent/JP5808536B2/ja active Active
- 2008-10-24 KR KR1020107011433A patent/KR101671452B1/ko active Active
- 2008-10-24 US US12/258,260 patent/US7736648B2/en active Active
- 2008-10-24 WO PCT/US2008/081175 patent/WO2009055711A2/en not_active Ceased
- 2008-10-24 NZ NZ585589A patent/NZ585589A/en not_active IP Right Cessation
- 2008-10-24 MX MX2010004482A patent/MX2010004482A/es active IP Right Grant
- 2008-10-24 CN CN200880117420.0A patent/CN101808663B/zh not_active Expired - Fee Related
- 2008-10-24 CA CA2703667A patent/CA2703667C/en active Active
-
2010
- 2010-04-22 IL IL205257A patent/IL205257A/en not_active IP Right Cessation
- 2010-05-04 ZA ZA2010/03131A patent/ZA201003131B/en unknown
- 2010-05-12 US US12/778,933 patent/US8273354B2/en active Active
-
2012
- 2012-09-25 US US13/626,852 patent/US9321830B2/en active Active
-
2015
- 2015-01-16 JP JP2015006644A patent/JP2015078231A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20100285022A1 (en) | 2010-11-11 |
| AU2008316703A2 (en) | 2010-07-22 |
| JP2011500091A (ja) | 2011-01-06 |
| US9321830B2 (en) | 2016-04-26 |
| CA2703667C (en) | 2015-12-29 |
| CN101808663B (zh) | 2015-09-30 |
| KR101671452B1 (ko) | 2016-11-17 |
| RU2010120879A (ru) | 2011-11-27 |
| US20130034564A1 (en) | 2013-02-07 |
| AU2008316703B2 (en) | 2012-09-27 |
| EP2214711A4 (en) | 2011-12-21 |
| WO2009055711A2 (en) | 2009-04-30 |
| CA2703667A1 (en) | 2009-04-30 |
| US20090130120A1 (en) | 2009-05-21 |
| US8273354B2 (en) | 2012-09-25 |
| NZ585589A (en) | 2012-07-27 |
| IL205257A0 (en) | 2010-12-30 |
| JP5808536B2 (ja) | 2015-11-10 |
| AU2008316703A1 (en) | 2009-04-30 |
| IL205257A (en) | 2014-12-31 |
| EP2214711A2 (en) | 2010-08-11 |
| KR20100091195A (ko) | 2010-08-18 |
| CN101808663A (zh) | 2010-08-18 |
| EP2214711B1 (en) | 2018-08-15 |
| US7736648B2 (en) | 2010-06-15 |
| BRPI0819210A2 (pt) | 2015-06-23 |
| RU2526517C2 (ru) | 2014-08-20 |
| JP2015078231A (ja) | 2015-04-23 |
| WO2009055711A3 (en) | 2009-09-24 |
| MX2010004482A (es) | 2010-07-06 |
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