ZA200904235B - Method for the enantioselective enzymatic reduction of secodione derivatives - Google Patents

Method for the enantioselective enzymatic reduction of secodione derivatives

Info

Publication number
ZA200904235B
ZA200904235B ZA200904235A ZA200904235A ZA200904235B ZA 200904235 B ZA200904235 B ZA 200904235B ZA 200904235 A ZA200904235 A ZA 200904235A ZA 200904235 A ZA200904235 A ZA 200904235A ZA 200904235 B ZA200904235 B ZA 200904235B
Authority
ZA
South Africa
Prior art keywords
enzymatic reduction
enantioselective enzymatic
secodione derivatives
secodione
derivatives
Prior art date
Application number
ZA200904235A
Other languages
English (en)
Inventor
Antje Gupta
Anke Tschentscher
Maria Bobkova
Original Assignee
Iep Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iep Gmbh filed Critical Iep Gmbh
Publication of ZA200904235B publication Critical patent/ZA200904235B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/38—Cyclopentanone- or cyclopentadione-containing products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200904235A 2006-12-07 2007-12-07 Method for the enantioselective enzymatic reduction of secodione derivatives ZA200904235B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0202706A AT504542B1 (de) 2006-12-07 2006-12-07 Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten

Publications (1)

Publication Number Publication Date
ZA200904235B true ZA200904235B (en) 2010-08-25

Family

ID=39492649

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904235A ZA200904235B (en) 2006-12-07 2007-12-07 Method for the enantioselective enzymatic reduction of secodione derivatives

Country Status (14)

Country Link
US (2) US20110020887A1 (fr)
EP (2) EP2087127B1 (fr)
JP (2) JP2010511394A (fr)
KR (2) KR101474816B1 (fr)
CN (2) CN101595224B (fr)
AT (2) AT504542B1 (fr)
AU (1) AU2007327842B2 (fr)
CA (1) CA2671319C (fr)
ES (2) ES2588706T3 (fr)
HU (1) HUE029907T2 (fr)
PL (2) PL2410047T3 (fr)
PT (1) PT2087127E (fr)
WO (1) WO2008068030A2 (fr)
ZA (1) ZA200904235B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI601825B (zh) * 2007-09-27 2017-10-11 Ｉｅｐ有限公司 對映異構選擇性酶催化還原中間產物之方法
MX2011013982A (es) 2009-06-22 2013-01-29 Sk Biopharmaceuticals Co Ltd Metodo para la preparacion de este ( r ) - 1 - aril - 2 - tetrazolil - etilico de acido carbomico.
US8404461B2 (en) 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
WO2013102619A2 (fr) 2012-01-04 2013-07-11 C-Lecta Gmbh Procédé de réduction d'un dérivé de secodione à l'aide d'une alcool-déshydrogénase
DE102012017026A1 (de) 2012-08-28 2014-03-06 Forschungszentrum Jülich GmbH Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
EP3607076A1 (fr) * 2017-04-07 2020-02-12 DSM IP Assets B.V. Hydroxylation régiosélective d'isophorone puis conversion en cétoisophorone
CN109112166B (zh) * 2017-06-26 2023-08-15 弈柯莱生物科技(上海)股份有限公司 酶法制备替卡格雷中间体
CN113025589B (zh) * 2021-04-21 2023-04-07 重庆第二师范学院 3α-羟基类固醇脱氢酶、编码基因及其在催化剂中的应用
EP4307919A2 (fr) * 2021-05-11 2024-01-24 Firmenich SA Procédé de fabrication de composés de gingérol et leur utilisation en tant que modificateurs d'arôme

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1252524A (en) * 1917-04-21 1918-01-08 Perry Wood W Spring-latch protector.
GB1230455A (fr) * 1967-05-22 1971-05-05
DE1768985C3 (de) * 1967-07-24 1980-12-18 Takeda Chemical Industries, Ltd., Osaka (Japan) Verfahren zur Herstellung von optisch aktiven Steroid-Verbindungen, die einen am 13 ß -Kohlenstoffatom (C1 bis C4)alkylsubstituierten 17-Hydroxy-8,14-secogona-polyen- 14-on-kern enthalten
US3697379A (en) * 1970-04-28 1972-10-10 American Home Prod Asymmetric reduction of seco-steroids
DE4014573C1 (fr) 1990-05-07 1991-10-10 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
EP0630402B1 (fr) * 1992-03-13 1997-06-04 Forschungszentrum Jülich Gmbh Nouvelle reductase d'esters cetoniques, fabrication et utilisation pour des reactions redox enzymatiques
CA2103932A1 (fr) * 1992-11-05 1994-05-06 Ramesh N. Patel Reduction stereoselective de cetones
JP3574682B2 (ja) 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
DE19610894A1 (de) 1996-03-20 1997-09-25 Leybold Ag Vorrichtung zum Ziehen von Einkristallen aus einer in einem Tiegel befindlichen Schmelze
DE19610984A1 (de) 1996-03-21 1997-09-25 Boehringer Mannheim Gmbh Alkohol-Dehydrogenase und deren Verwendung zur enzymatischen Herstellung chiraler Hydroxyverbindungen
CZ20012792A3 (cs) * 1999-12-03 2002-03-13 Kaneka Corporation Polypeptid, polynukleotid kódující polypeptid, expresní vektor, transformant a způsob přípravy
DE10119274A1 (de) 2001-04-20 2002-10-31 Juelich Enzyme Products Gmbh Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen
DE10327454A1 (de) 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
DE102005044736A1 (de) * 2005-09-19 2007-03-22 Basf Ag Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
AT503017B1 (de) * 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen

Also Published As

Publication number Publication date
CA2671319A1 (fr) 2008-06-12
AT504542B1 (de) 2008-09-15
KR20110107874A (ko) 2011-10-04
US20120040424A1 (en) 2012-02-16
PL2410047T3 (pl) 2016-12-30
PT2087127E (pt) 2012-06-20
ES2386380T3 (es) 2012-08-20
WO2008068030A3 (fr) 2008-12-18
JP2012005497A (ja) 2012-01-12
CA2671319C (fr) 2016-02-23
CN102382805A (zh) 2012-03-21
EP2087127B1 (fr) 2012-04-18
CN101595224A (zh) 2009-12-02
KR101445191B1 (ko) 2014-10-16
AU2007327842B2 (en) 2013-02-28
EP2410047B9 (fr) 2016-08-24
KR101474816B1 (ko) 2014-12-19
CN101595224B (zh) 2014-04-02
JP5627546B2 (ja) 2014-11-19
AU2007327842A1 (en) 2008-06-12
ATE554181T1 (de) 2012-05-15
CN102382805B (zh) 2015-03-25
EP2087127A2 (fr) 2009-08-12
EP2410047B1 (fr) 2016-06-01
PL2087127T3 (pl) 2012-11-30
ES2588706T3 (es) 2016-11-04
EP2410047A1 (fr) 2012-01-25
US8323936B2 (en) 2012-12-04
KR20090096511A (ko) 2009-09-10
AT504542A1 (de) 2008-06-15
JP2010511394A (ja) 2010-04-15
WO2008068030A2 (fr) 2008-06-12
US20110020887A1 (en) 2011-01-27
HUE029907T2 (hu) 2017-04-28

Similar Documents

Publication Publication Date Title
GB0619753D0 (en) Enzyme inhibitors
PL1903019T3 (pl) Sposób wytwarzania izoolefin
IL201174A0 (en) Enzymatic method for the production of microcapsules
ZA200904235B (en) Method for the enantioselective enzymatic reduction of secodione derivatives
IL194339A0 (en) Enzyme inhibitors
IL194735A (en) METHOD FOR SELECTING Stereo Selection of Morphinone History
PL2772543T3 (pl) Enzymatyczny proces wytwarzania beta-santalenu i odpowiadającego mu enzymu
ZA201001052B (en) Process for the enantioselective enzymatic reduction of intermediates
SI1926821T1 (sl) Postopek za enantioselektivno encimatsko redukcijo keto spojin
EP1923402A4 (fr) Procédé de détermination de l'activité enzymatique
GB0608844D0 (en) Enzyme inhibitors
GB2455481B (en) Process for the enzymatic removal of filter-cakes produced by water -based drilling and completion fluids
GB0617161D0 (en) Enzyme inhibitors
EP1930419A4 (fr) Methode pour produire une enzyme
ZA200900636B (en) Method of prognosis
HK1134925A1 (en) Method for the production of benzofuran-2-carboxamides
ZA200610469B (en) Enzymatic oil-degumming method
ZA200903936B (en) Method for the production of an agent against an infectuous disease
PL382757A1 (pl) Sposób skojarzonego wytwarzania enzymatycznych hydrolizatów skrobiowych
AU2006902292A0 (en) Method for the production of chelation agent
AU2005900743A0 (en) Method for post - signing modifications of software
AU2006900509A0 (en) Method
GB0612544D0 (en) Enzyme inhibitors
GB0624958D0 (en) Enzyme inhibitors
ZA200808237B (en) Enzyme inhibitors