ZA200903567B - Isosorbide mononitrate derivatives for the treatment of intestinal disorders - Google Patents

Isosorbide mononitrate derivatives for the treatment of intestinal disorders

Info

Publication number
ZA200903567B
ZA200903567B ZA200903567A ZA200903567A ZA200903567B ZA 200903567 B ZA200903567 B ZA 200903567B ZA 200903567 A ZA200903567 A ZA 200903567A ZA 200903567 A ZA200903567 A ZA 200903567A ZA 200903567 B ZA200903567 B ZA 200903567B
Authority
ZA
South Africa
Prior art keywords
treatment
isosorbide mononitrate
intestinal disorders
mononitrate derivatives
derivatives
Prior art date
Application number
ZA200903567A
Other languages
English (en)
Inventor
Moliner Jose Repolles
Coy Francisco Pubill
Mancini Marisabel Mourelle
Original Assignee
Lacer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38043051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200903567(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lacer Sa filed Critical Lacer Sa
Publication of ZA200903567B publication Critical patent/ZA200903567B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200903567A 2006-12-28 2007-12-27 Isosorbide mononitrate derivatives for the treatment of intestinal disorders ZA200903567B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06380338A EP1941876A1 (en) 2006-12-28 2006-12-28 Isosorbide mononitrate derivatives for the treatment of Inflammation and ocular hypertension

Publications (1)

Publication Number Publication Date
ZA200903567B true ZA200903567B (en) 2010-08-25

Family

ID=38043051

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200903567A ZA200903567B (en) 2006-12-28 2007-12-27 Isosorbide mononitrate derivatives for the treatment of intestinal disorders
ZA200903566A ZA200903566B (en) 2006-12-28 2007-12-27 Isosorbide mononitrate derivatives for the treatment of ocular hypertension

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200903566A ZA200903566B (en) 2006-12-28 2007-12-27 Isosorbide mononitrate derivatives for the treatment of ocular hypertension

Country Status (21)

Country Link
US (1) US20080161389A1 (es)
EP (3) EP1941876A1 (es)
JP (2) JP2010514734A (es)
KR (2) KR20100100584A (es)
CN (2) CN101600425A (es)
AR (1) AR064543A1 (es)
AT (2) ATE472324T1 (es)
AU (2) AU2007341218B2 (es)
BR (2) BRPI0720664A2 (es)
CA (2) CA2674144A1 (es)
CL (2) CL2007003837A1 (es)
DE (2) DE602007007523D1 (es)
ES (3) ES2324130B1 (es)
IL (2) IL198912A0 (es)
MX (2) MX2009007038A (es)
NO (2) NO20092763L (es)
PL (2) PL2114398T3 (es)
RU (2) RU2009128968A (es)
UY (1) UY30847A1 (es)
WO (2) WO2008080939A1 (es)
ZA (2) ZA200903567B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2149576A1 (en) * 2008-07-22 2010-02-03 Lacer, S.A. Isosorbide Nitrates having vasodilating activity
EP2149577B1 (en) * 2008-07-22 2011-04-27 Lacer, S.A. New stereospecific method for the preparation of dioxa-bicyclooctane compounds
EP2177216A1 (en) * 2008-10-13 2010-04-21 Lacer, S.A. Use of dianhydrohexite mononitrate derivatives as healing agents
WO2010055138A1 (en) * 2008-11-14 2010-05-20 Lacer, S.A. New stereospecific method for the preparation of dioxa-bicyclooctane compounds
EP2199294A1 (en) * 2008-12-19 2010-06-23 Lacer, S.A. New stereospecific method for the preparation of dioxa bicyclooctane nitrate compounds
EP2515899B1 (en) * 2009-12-23 2016-05-25 ARCA biopharma, Inc. Methods and compositions for cardiovascular diseases and conditions
US20160016969A1 (en) * 2013-03-05 2016-01-21 Archer Daniels Midland Company Isohexide monotriflates and process for synthesis thereof
WO2018224419A1 (en) 2017-06-06 2018-12-13 Nicox S.A. Nitric oxide donating isomannide derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2739689C2 (de) * 1977-09-02 1986-10-16 Euratom Thermische Wärmepumpe
JPS60149521A (ja) * 1984-01-18 1985-08-07 Eisai Co Ltd 高眼圧・緑内障治療・予防用点眼剤
US5573758A (en) * 1995-04-28 1996-11-12 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
US5925342A (en) * 1996-11-13 1999-07-20 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
GB9720797D0 (en) * 1997-09-30 1997-12-03 Rhodes John Pharmaceutical composition for the treatment of inflammatory bowel disease and irritable bowel syndrome
ES2142773B1 (es) * 1998-10-07 2001-01-01 Lacer Sa Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida.
WO2002060449A2 (de) * 2001-01-31 2002-08-08 Merck Patent Gmbh Pharmazeutische formulierung enthaltend pyrazolo[4,3-d]pyrimidine und nitrate oder thienopyrimidine und nitrate
DE60326226D1 (de) * 2002-03-21 2009-04-02 Cayman Chemical Co Prostaglandin f2 alpha analoga in kombination mit einem antimikrobiellen mittel zur behandlung von glaukom
CN1863905A (zh) * 2003-09-08 2006-11-15 得克萨斯系统大学董事会 通过用前列腺素或前列腺素类似物补充培养基加强体外胚发育的方法以及组合物
ES2258365B1 (es) * 2003-10-03 2007-12-01 Lacer, S.A. Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.

Also Published As

Publication number Publication date
EP2114398A1 (en) 2009-11-11
EP2124930B1 (en) 2010-10-13
CA2674144A1 (en) 2008-07-10
US20080161389A1 (en) 2008-07-03
EP2114398B1 (en) 2010-06-30
ZA200903566B (en) 2010-08-25
CN101600426B (zh) 2012-07-25
JP2010514734A (ja) 2010-05-06
ATE484279T1 (de) 2010-10-15
CN101600426A (zh) 2009-12-09
BRPI0720664A2 (pt) 2014-01-14
CL2007003836A1 (es) 2008-07-11
PL2114398T3 (pl) 2010-11-30
ES2324130A1 (es) 2009-07-30
IL198941A0 (en) 2010-02-17
MX2009007038A (es) 2009-08-25
AU2007341289B2 (en) 2010-08-26
WO2008080955A1 (en) 2008-07-10
EP1941876A1 (en) 2008-07-09
ES2348314T3 (es) 2010-12-02
NO20092764L (no) 2009-07-27
DE602007009877D1 (de) 2010-11-25
CA2674550A1 (en) 2008-07-10
KR20100100584A (ko) 2010-09-15
AR064543A1 (es) 2009-04-08
AU2007341289A1 (en) 2008-07-10
JP2010514733A (ja) 2010-05-06
AU2007341218B2 (en) 2010-09-09
IL198912A0 (en) 2010-02-17
CL2007003837A1 (es) 2008-07-11
CN101600425A (zh) 2009-12-09
RU2009128968A (ru) 2011-02-10
BRPI0720663A2 (pt) 2014-01-14
WO2008080939A1 (en) 2008-07-10
ES2354317T3 (es) 2011-03-14
ATE472324T1 (de) 2010-07-15
KR20090112673A (ko) 2009-10-28
EP2124930A1 (en) 2009-12-02
NO20092763L (no) 2009-07-27
RU2009128970A (ru) 2011-02-10
UY30847A1 (es) 2008-05-31
PL2124930T3 (pl) 2011-04-29
ES2324130B1 (es) 2010-03-22
DE602007007523D1 (de) 2010-08-12
AU2007341218A1 (en) 2008-07-10
MX2009007040A (es) 2009-08-25

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