ZA200903566B - Isosorbide mononitrate derivatives for the treatment of ocular hypertension - Google Patents
Isosorbide mononitrate derivatives for the treatment of ocular hypertensionInfo
- Publication number
- ZA200903566B ZA200903566B ZA200903566A ZA200903566A ZA200903566B ZA 200903566 B ZA200903566 B ZA 200903566B ZA 200903566 A ZA200903566 A ZA 200903566A ZA 200903566 A ZA200903566 A ZA 200903566A ZA 200903566 B ZA200903566 B ZA 200903566B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- ocular hypertension
- isosorbide mononitrate
- mononitrate derivatives
- derivatives
- Prior art date
Links
- 206010030043 Ocular hypertension Diseases 0.000 title 1
- YWXYYJSYQOXTPL-SLPGGIOYSA-N isosorbide mononitrate Chemical class [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@@H]21 YWXYYJSYQOXTPL-SLPGGIOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06380338A EP1941876A1 (fr) | 2006-12-28 | 2006-12-28 | Derivés du mononitrite de l'isosorbide destinées au traitement de l'inflammation et l'hypertension oculaire |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200903566B true ZA200903566B (en) | 2010-08-25 |
Family
ID=38043051
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200903567A ZA200903567B (en) | 2006-12-28 | 2007-12-27 | Isosorbide mononitrate derivatives for the treatment of intestinal disorders |
ZA200903566A ZA200903566B (en) | 2006-12-28 | 2007-12-27 | Isosorbide mononitrate derivatives for the treatment of ocular hypertension |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200903567A ZA200903567B (en) | 2006-12-28 | 2007-12-27 | Isosorbide mononitrate derivatives for the treatment of intestinal disorders |
Country Status (21)
Country | Link |
---|---|
US (1) | US20080161389A1 (fr) |
EP (3) | EP1941876A1 (fr) |
JP (2) | JP2010514733A (fr) |
KR (2) | KR20090112673A (fr) |
CN (2) | CN101600425A (fr) |
AR (1) | AR064543A1 (fr) |
AT (2) | ATE484279T1 (fr) |
AU (2) | AU2007341218B2 (fr) |
BR (2) | BRPI0720663A2 (fr) |
CA (2) | CA2674144A1 (fr) |
CL (2) | CL2007003836A1 (fr) |
DE (2) | DE602007009877D1 (fr) |
ES (3) | ES2324130B1 (fr) |
IL (2) | IL198912A0 (fr) |
MX (2) | MX2009007038A (fr) |
NO (2) | NO20092763L (fr) |
PL (2) | PL2124930T3 (fr) |
RU (2) | RU2009128970A (fr) |
UY (1) | UY30847A1 (fr) |
WO (2) | WO2008080939A1 (fr) |
ZA (2) | ZA200903567B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2149577B1 (fr) * | 2008-07-22 | 2011-04-27 | Lacer, S.A. | Nouveau procédé stéréospécifique pour la préparation de composés de dioxa-bicyclooctane |
EP2149576A1 (fr) * | 2008-07-22 | 2010-02-03 | Lacer, S.A. | Nitrates d'isosorbide ayant une activité vasodilatatrice |
EP2177216A1 (fr) * | 2008-10-13 | 2010-04-21 | Lacer, S.A. | Utilisation de dérivés de mononitrate de dianhydrohexite comme agents de cicatrisation |
WO2010055138A1 (fr) * | 2008-11-14 | 2010-05-20 | Lacer, S.A. | Nouveau procédé stéréospécifique pour la préparation de composés de dioxabicyclooctane |
EP2199294A1 (fr) * | 2008-12-19 | 2010-06-23 | Lacer, S.A. | Nouveau procédé stéréospécifique pour la préparation de composé de nitrate de dioxa bicyclooctane |
DK2515899T3 (en) * | 2009-12-23 | 2016-08-15 | Arca Biopharma Inc | METHODS AND COMPOSITIONS FOR CARDIOVASCULAR DISEASES AND CONDITIONS |
US20160016969A1 (en) * | 2013-03-05 | 2016-01-21 | Archer Daniels Midland Company | Isohexide monotriflates and process for synthesis thereof |
WO2018224419A1 (fr) | 2017-06-06 | 2018-12-13 | Nicox S.A. | Dérivés d'isomannide donneurs d'oxyde nitrique |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2739689C2 (de) * | 1977-09-02 | 1986-10-16 | Euratom | Thermische Wärmepumpe |
JPS60149521A (ja) * | 1984-01-18 | 1985-08-07 | Eisai Co Ltd | 高眼圧・緑内障治療・予防用点眼剤 |
US5573758A (en) * | 1995-04-28 | 1996-11-12 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers |
US5925342A (en) * | 1996-11-13 | 1999-07-20 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers |
GB9720797D0 (en) * | 1997-09-30 | 1997-12-03 | Rhodes John | Pharmaceutical composition for the treatment of inflammatory bowel disease and irritable bowel syndrome |
ES2142773B1 (es) * | 1998-10-07 | 2001-01-01 | Lacer Sa | Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida. |
US20040077664A1 (en) * | 2001-01-31 | 2004-04-22 | Hans-Michael Eggenweiler | Pharmaceutical formulation comprising pyrazolo[4,3-d]pyrimidine and nitrates or thienopyrimidines and nitrates |
AU2003222049B2 (en) * | 2002-03-21 | 2007-05-31 | Cayman Chemical Company, Incorporated | Prostaglandin F2 alpha analogs in combination with antimicrobials for treating glaucoma |
JP2007504807A (ja) * | 2003-09-08 | 2007-03-08 | ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 培養培地にプロスタグランジン又はプロスタグランジン類似物を補足することによってインビトロ胚発生を高めるための方法及び組成 |
ES2258365B1 (es) * | 2003-10-03 | 2007-12-01 | Lacer, S.A. | Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos. |
-
2006
- 2006-12-28 EP EP06380338A patent/EP1941876A1/fr not_active Withdrawn
-
2007
- 2007-01-23 ES ES200700181A patent/ES2324130B1/es not_active Expired - Fee Related
- 2007-03-01 US US11/680,691 patent/US20080161389A1/en not_active Abandoned
- 2007-12-27 RU RU2009128970/15A patent/RU2009128970A/ru not_active Application Discontinuation
- 2007-12-27 ES ES07858167T patent/ES2348314T3/es active Active
- 2007-12-27 CN CNA2007800441623A patent/CN101600425A/zh active Pending
- 2007-12-27 MX MX2009007038A patent/MX2009007038A/es active IP Right Grant
- 2007-12-27 MX MX2009007040A patent/MX2009007040A/es active IP Right Grant
- 2007-12-27 UY UY30847A patent/UY30847A1/es not_active Application Discontinuation
- 2007-12-27 CA CA002674144A patent/CA2674144A1/fr not_active Abandoned
- 2007-12-27 EP EP07858187A patent/EP2124930B1/fr active Active
- 2007-12-27 AU AU2007341218A patent/AU2007341218B2/en not_active Ceased
- 2007-12-27 ES ES07858187T patent/ES2354317T3/es active Active
- 2007-12-27 KR KR1020097015821A patent/KR20090112673A/ko not_active Application Discontinuation
- 2007-12-27 BR BRPI0720663-1A patent/BRPI0720663A2/pt not_active IP Right Cessation
- 2007-12-27 EP EP07858167A patent/EP2114398B1/fr active Active
- 2007-12-27 AU AU2007341289A patent/AU2007341289B2/en not_active Ceased
- 2007-12-27 ZA ZA200903567A patent/ZA200903567B/xx unknown
- 2007-12-27 ZA ZA200903566A patent/ZA200903566B/xx unknown
- 2007-12-27 CL CL200703836A patent/CL2007003836A1/es unknown
- 2007-12-27 AR ARP070105911A patent/AR064543A1/es unknown
- 2007-12-27 KR KR1020097015820A patent/KR20100100584A/ko not_active Application Discontinuation
- 2007-12-27 PL PL07858187T patent/PL2124930T3/pl unknown
- 2007-12-27 WO PCT/EP2007/064570 patent/WO2008080939A1/fr active Application Filing
- 2007-12-27 AT AT07858187T patent/ATE484279T1/de not_active IP Right Cessation
- 2007-12-27 PL PL07858167T patent/PL2114398T3/pl unknown
- 2007-12-27 AT AT07858167T patent/ATE472324T1/de not_active IP Right Cessation
- 2007-12-27 DE DE602007009877T patent/DE602007009877D1/de active Active
- 2007-12-27 JP JP2009543471A patent/JP2010514733A/ja active Pending
- 2007-12-27 BR BRPI0720664-0A patent/BRPI0720664A2/pt not_active IP Right Cessation
- 2007-12-27 WO PCT/EP2007/064591 patent/WO2008080955A1/fr active Application Filing
- 2007-12-27 CN CN2007800443012A patent/CN101600426B/zh not_active Expired - Fee Related
- 2007-12-27 JP JP2009543474A patent/JP2010514734A/ja active Pending
- 2007-12-27 CL CL200703837A patent/CL2007003837A1/es unknown
- 2007-12-27 DE DE602007007523T patent/DE602007007523D1/de active Active
- 2007-12-27 RU RU2009128968/15A patent/RU2009128968A/ru not_active Application Discontinuation
- 2007-12-27 CA CA002674550A patent/CA2674550A1/fr not_active Abandoned
-
2009
- 2009-05-24 IL IL198912A patent/IL198912A0/en unknown
- 2009-05-25 IL IL198941A patent/IL198941A0/en unknown
- 2009-07-27 NO NO20092763A patent/NO20092763L/no not_active Application Discontinuation
- 2009-07-27 NO NO20092764A patent/NO20092764L/no not_active Application Discontinuation
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