ZA200810024B - Process for the synthesis of ibandronate sodium - Google Patents

Process for the synthesis of ibandronate sodium

Info

Publication number
ZA200810024B
ZA200810024B ZA200810024A ZA200810024A ZA200810024B ZA 200810024 B ZA200810024 B ZA 200810024B ZA 200810024 A ZA200810024 A ZA 200810024A ZA 200810024 A ZA200810024 A ZA 200810024A ZA 200810024 B ZA200810024 B ZA 200810024B
Authority
ZA
South Africa
Prior art keywords
synthesis
ibandronate sodium
present
ibandronate
sodium
Prior art date
Application number
ZA200810024A
Other languages
English (en)
Inventor
Rao Dharamaj Ramchandra
Kankan Rajendra Narayanrao
Ghagare Maruti Ganpati
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of ZA200810024B publication Critical patent/ZA200810024B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200810024A 2006-06-23 2008-11-25 Process for the synthesis of ibandronate sodium ZA200810024B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN994MU2006 2006-06-23

Publications (1)

Publication Number Publication Date
ZA200810024B true ZA200810024B (en) 2009-10-28

Family

ID=39144580

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810024A ZA200810024B (en) 2006-06-23 2008-11-25 Process for the synthesis of ibandronate sodium

Country Status (11)

Country Link
US (1) US8178712B2 (de)
EP (1) EP2038291B1 (de)
JP (1) JP5571378B2 (de)
KR (1) KR101425429B1 (de)
AT (1) ATE473990T1 (de)
AU (1) AU2007298508B2 (de)
CA (1) CA2652420C (de)
DE (1) DE602007007773D1 (de)
NZ (1) NZ573137A (de)
WO (1) WO2008035367A2 (de)
ZA (1) ZA200810024B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008004000A1 (en) * 2006-07-03 2008-01-10 Generics [Uk] Limited Novel process for the preparation of bisphosphonic acids
CN102093416B (zh) * 2011-03-17 2013-07-24 南京恒生制药有限公司 一种合成伊班膦酸钠的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
JPS5414931A (en) * 1977-07-05 1979-02-03 Seitetsu Kagaku Co Ltd Preparation of n-benzylglycine
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
JPS63190868A (ja) * 1986-08-21 1988-08-08 Kanegafuchi Chem Ind Co Ltd 光学活性スルホニルオキシ化合物及びその化合物を用いる光学活性アミンの製造方法
JPH11322687A (ja) * 1998-05-12 1999-11-24 Koei Chem Co Ltd ホルムアミド類の製造方法
JPH11349494A (ja) * 1998-06-03 1999-12-21 Toray Ind Inc 光学分割用分離剤および光学異性体の吸着分離方法
JP2001294558A (ja) * 2000-04-12 2001-10-23 Honshu Chem Ind Co Ltd ノルボルネンー２−カルボン酸エステル類及びその製造方法
CA2536229C (en) 2003-08-21 2012-09-25 Sun Pharmaceutical Industries Limited A process for preparation of bisphosphonic acid compounds
JP4191008B2 (ja) * 2003-11-04 2008-12-03 花王株式会社 アミノカルボン酸エステルの製造法
DE602004032577D1 (de) 2003-12-23 2011-06-16 Alchymars S P A Amorphe Form das Natriumsalzes der Ibandronsäure
WO2006002348A2 (en) * 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid
US7214818B2 (en) * 2004-10-29 2007-05-08 Hoffmann-La Roche Inc. Method for synthesizing bisphosphonate

Also Published As

Publication number Publication date
EP2038291A2 (de) 2009-03-25
EP2038291B1 (de) 2010-07-14
KR20090023394A (ko) 2009-03-04
US20100228052A1 (en) 2010-09-09
WO2008035367A3 (en) 2008-05-22
WO2008035367A2 (en) 2008-03-27
WO2008035367B1 (en) 2008-08-07
JP2009541305A (ja) 2009-11-26
ATE473990T1 (de) 2010-07-15
KR101425429B1 (ko) 2014-08-01
CA2652420A1 (en) 2008-03-27
CA2652420C (en) 2014-01-14
DE602007007773D1 (de) 2010-08-26
AU2007298508A1 (en) 2008-03-27
US8178712B2 (en) 2012-05-15
JP5571378B2 (ja) 2014-08-13
NZ573137A (en) 2011-03-31
AU2007298508B2 (en) 2012-02-09

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